Results 11 to 20 of about 94,951 (115)
Characterisation of the PQQ cofactor radical in quinoprotein ethanol dehydrogenase of Pseudomonas aeruginosa by electron paramagnetic resonance spectroscopy [PDF]
FEBS Letters, 2004 The binding pocket of the pyrroloquinoline quinone (PQQ) cofactor in quinoprotein alcohol dehydrogenases contains a characteristic disulphide ring formed by two adjacent cysteine residues. To analyse the function of this unusual structural motif we have investigated the wild‐type and a double cysteine:alanine mutant of the quinoprotein ethanol ...
Kay, Christopher W.M +3 more
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PQQ Dietary Supplementation Prevents Alkylating Agent-Induced Ovarian Dysfunction in Mice
Frontiers in Endocrinology, 2022 Alkylating agents (AAs) that are commonly used for cancer therapy cause great damage to the ovary. Pyrroloquinoline-quinine (PQQ), which was initially identified as a redox cofactor for bacterial dehydrogenases, has been demonstrated to benefit the ...
Xiuliang Dai +8 more
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Pyrroloquinoline Quinone (PQQ): Its impact on human health and potential benefits
Current Research in Food SciencePyrroloquinoline Quinone (PQQ) is a redox-active quinone molecule with significant implications for human health. Originally identified as a bacterial cofactor, PQQ has since been lauded for its diverse biological and therapeutic activities. It serves as
Tingdong Yan +10 more
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Deciphering the assembly process of PQQ dependent methanol dehydrogenase
Nature CommunicationsPyrroloquinoline quinone (PQQ)-dependent methanol dehydrogenases (MDHs), the periplasmic metalloenzymes in Gram-negative methylotrophic bacteria, play a pivotal role in methane and methanol bio-utilization.
Haichuan Zhou +16 more
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Journal of Animal Science and Biotechnology, 2019 Background Pyrroloquinoline quinone (PQQ), which is a water soluble, thermo-stable triglyceride-quinone, is widely distributed in nature and characterized as a mammalian vitamin-like redox cofactor.
Boru Zhang +6 more
doaj +2 more sources
Discovery of a eukaryotic pyrroloquinoline quinone-dependent oxidoreductase belonging to a new auxiliary activity family in the database of carbohydrate-active enzymes. [PDF]
PLoS ONE, 2014 Pyrroloquinoline quinone (PQQ) is a redox cofactor utilized by a number of prokaryotic dehydrogenases. Not all prokaryotic organisms are capable of synthesizing PQQ, even though it plays important roles in the growth and development of many organisms ...
Hirotoshi Matsumura +9 more
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Biomolecules, 2021 Pyrroloquinoline quinone (PQQ) is associated with biological processes such as mitochondriogenesis, reproduction, growth, and aging. In addition, PQQ attenuates clinically relevant dysfunctions (e.g., those associated with ischemia, inflammation and ...
Karen R. Jonscher +2 more
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PQQ-linked extracellular glucose oxidation and chemotaxis towards this cofactor in rhizobia [PDF]
FEMS Microbiology Letters, 1996 The presence of the pyrroloquinoline quinone (PQQ)-dependent glucose dehydrogenase in several strains of different Rhizobium species and of Bradyrhizobium japonicum was investigated. It was found that most strains were only able to synthesize the apo-enzyme, whereas in three strains, Rhizobium meliloti 102F34 and Bradyrhizobium japonicum strains ...
Boiardi, J.L. +2 more
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npj Aging, 2022 The aim of this study was to investigate the effects of pyrroloquinoline quinone (PQQ), an oxidoreductase cofactor, on the H 2 O 2 -induced premature senescence model in HEI-OC1 auditory cells and to elucidate its mechanism of action in vitro. Cells were
Ying Gao +4 more
semanticscholar +2 more sources
Effects of pyrroloquinoline quinone on noise-induced and age-related hearing loss in mice
Scientific Reports, 2022 We investigated whether the oxidoreductase cofactor pyrroloquinoline quinone (PQQ) prevents noise-induced and age-related hearing loss (NIHL and ARHL) in mice.
Ying Gao +4 more
doaj +1 more source