Results 11 to 20 of about 31,406 (163)

Protective Effect of Pyrroloquinoline Quinone (PQQ) against Renal Ischemia-Reperfusion Injury in Rat [PDF]

Iranian Journal of Veterinary Surgery, 2023
Ischemia/reperfusion can cause tissue damage and affect organ function. Ischemia-reperfusion injury (IRI) occurs in a variety of clinical manifestations such as stroke, trauma, and surgery.
Elnaz Taheran, Vahid Mohammadi, Rahim Mohammadi   +2 more
doaj   +3 more sources

Deep Learning‐Driven Exploration of Pyrroloquinoline Quinone Neuroprotective Activity in Alzheimer's Disease [PDF]

Advanced Science
Alzheimer's disease (AD) is a pressing concern in neurodegenerative research. To address the challenges in AD drug development, especially those targeting Aβ, this study uses deep learning and a pharmacological approach to elucidate the potential of ...
Xinuo Li, Yuan Sun, Zheng Zhou, Jinran Li, Sai Liu, Long Chen, Yiting Shi, Min Wang, Zheying Zhu, Guangji Wang, Qiulun Lu   +10 more
doaj   +3 more sources

Pyrroloquinoline-Quinone Is More Than an Antioxidant: A Vitamin-like Accessory Factor Important in Health and Disease Prevention

Biomolecules, 2021
Pyrroloquinoline quinone (PQQ) is associated with biological processes such as mitochondriogenesis, reproduction, growth, and aging. In addition, PQQ attenuates clinically relevant dysfunctions (e.g., those associated with ischemia, inflammation and ...
Robert Rucker, Karen R Jonscher
exaly   +3 more sources

Fabrication of pyrroloquinoline quinone-loaded small unilamellar vesicles through various downsizing techniques for biomedical applications

OpenNano
Treatment of injuries to bone structure represents a significant economic burden for health care institutions and systems worldwide. The development of tissue engineering scaffolds has expanded to include the incorporation of nanotechnology platforms ...
Gerardo Garcia-Zavaleta, Daniel Mejia-Valdez, Hamed Hosseinian, Ciro A. Rodriguez, Geoffrey A. Cordell, Yadira I. Vega-Cantu, Aida Rodriguez-Garcia   +6 more
doaj   +2 more sources

Pyrroloquinoline Quinone Improved Boar Sperm Quality via Maintaining Mitochondrial Function During Cryopreservation [PDF]

Antioxidants
Due to oxidative damage and mitochondrial dysfunction, boar semen cryopreservation remains a significant challenge. This study investigates the effects of pyrroloquinoline quinone (PQQ), a mitochondrial-targeted antioxidant, on the post-thaw boar sperm ...
Shanpeng Wang, Qi Wang, Lingjiang Min, Hailiang Cao, Adedeji O. Adetunji, Kaifeng Zhou, Zhendong Zhu   +6 more
doaj   +2 more sources

Contrast Sensitivity, Quality of Life, and Reading Performance in Glaucoma: A Randomized Crossover Study Comparing Citicoline 500 mg/Homotaurine 50 mg/Nicotinamide 54 mg/Pyrroloquinoline Quinone 5 mg and Citicoline 500 mg [PDF]

Brain Sciences
Background/Objectives: This study aimed to compare oral citicoline 500 mg/homotaurine 50 mg/nicotinamide 54 mg/pyrroloquinoline quinone 5 mg (CIT/HOMO/B3/PQQ) with citicoline 500 mg alone (CIT500) for contrast sensitivity (CS), vision-related quality of ...
Luca Agnifili, Davide Celani, Matteo Fornaro, Alessandro Sferra, Rodolfo Mastropasqua, Ciro Costagliola   +5 more
doaj   +2 more sources

Pyrroloquinoline Quinone Attenuates Traumatic Brain Injury-Induced Secondary Damage by Activating PINK1/Parkin-Mediated Mitophagy and Suppressing ASS1/CPS1-Driven Arginine Biosynthesis. [PDF]

CNS Neurosci Ther
Pyrroloquinoline quinone (PQQ) attenuates traumatic brain injury in mice. Multi‐omics integration and molecular docking reveal that PQQ activates PINK1/Parkin‐mediated mitophagy to restore mitochondrial homeostasis while suppressing ASS1/CPS1‐driven arginine biosynthesis to dampen neuroinflammation, identifying a dual‐axis therapeutic mechanism for TBI.
He Y, Yu L, Lu Y, Zhou Z, Li A, Wang L, Huang Z, Liu Y, Ma Y, Mi W.   +9 more
europepmc   +2 more sources

Endophytic Biostimulant Pyrroloquinoline Quinone Enhances Banana Growth and Primes Immunity Against Fusarium Wilt. [PDF]

Physiol Plant
ABSTRACT Pyrroloquinoline quinone (PQQ) is a redox cofactor derived from prokaryotes that participates in various biological processes involving dehydrogenase enzymes. Previous field trials identified a PQQ‐producing endophyte, Burkholderia seminalis 869T2, which enhances banana growth and reduces Fusarium wilt incidence from 24.5% to 3.4%.
Hung SW, Yu MY, Liu CH, Huang TC, Peng JH, Jang NY, Kuo CH, Yang YL, Ho YN, Chiang EI, Hwang HH, Huang CC.   +11 more
europepmc   +2 more sources

Solid Phase Extraction of Pyrroloquinoline Quinone by Surface Modified Magnetic Nano Materials

Shipin gongye ke-ji, 2023
In this study, three kinds of nanomaterials with silanized or ion pair silanized surface modifications were synthesized, and the extraction and adsorption properties of these three materials for pyrroloquinoline quinone were studied.
Ke MA, Yuanhang CHENG
doaj   +1 more source

Effects of Pyrroloquinoline Quinone (PQQ) and Coenzyme Q10 on mitochondrial genes, mitomiRs and cellular properties in HepG2 cell line [PDF]

, 2023
Our study aimed to reveal the effects and changes, antioxidant metabolism (Oxidative Stress), inflammatory response, mitochondrial biogenesis and mitochondrial dysfunction characteristics in hepatocellular carcinoma cell line HepG2; that occur in ...
Muhammed Ali Nalbant, Nalbant, Muhammed Ali, Eroğlu, Onur, Onur Eroğlu   +3 more
core   +3 more sources