Results 41 to 50 of about 24,139 (199)

VIVID: A qPCR‐Based Platform for Sensitive and Quantitative In Vivo Tracking of Extracellular Vesicles

Advanced Functional Materials, EarlyView.
This study introduces VIVID (Vesicle In Vivo Identification using DNA), a qPCR‐based platform that tracks PCR‐amplifiable DNA tags loaded in the EVs for accurate and quantifiable EV biodistribution in vivo. ABSTRACT Extracellular vesicles (EVs) represent promising carriers for nucleic acid therapeutics, offering advantages over synthetic nanoparticles ...
Oscar Boyadjian, Talin Ebrahimian, Jonathan Miranda O'Connor, Janusz Rak, Stephanie Lehoux, Maryam Tabrizian   +5 more
wiley   +1 more source

Scalable desolvation synthesis, storage stability, and comprehensive biophysical characterization of human hemoglobin nanoparticles as a potential hemoglobin‐based oxygen carrier

Biotechnology Progress, EarlyView.
This work describes the development of human hemoglobin nanoparticles using an anti‐solvent precipitation synthesis method as a potential next generation hemoglobin‐based oxygen carrier. The hemoglobin nanoparticles are uniform in size and shape, hemocompatible, stable at various storage conditions, and demonstrate a scalable synthesis technique ...
Alisyn Greenfield, Andre F. Palmer
wiley   +1 more source

Methemoglobin levels in malaria: a systematic review and meta-analysis of its association with Plasmodium falciparum and Plasmodium vivax infections and disease severity

Scientific Reports
Reports indicate that Plasmodium infections influence methemoglobin levels. However, findings have been inconclusive or have varied across different geographic and demographic contexts.
Manas Kotepui, Aongart Mahittikorn, Polrat Wilairatana, Frederick Ramirez Masangkay, Kinley Wangdi, Kwuntida Uthaisar Kotepui   +5 more
doaj   +1 more source

Brain iron accumulation in unexplained fetal and infant death victims with smoker mothers-The possible involvement of maternal methemoglobinemia

BMC Pediatrics, 2011
Background Iron is involved in important vital functions as an essential component of the oxygen-transporting heme mechanism. In this study we aimed to evaluate whether oxidative metabolites from maternal cigarette smoke could affect iron homeostasis in ...
Corna Melissa F, Alfonsi Graziella, Mohorovic Lucijan, Lavezzi Anna M, Matturri Luigi   +4 more
doaj   +1 more source

Nutritional Potential, Phytochemical Content, In Vivo Antioxidant, and Antanemic Potential of Musa paradisiaca Flower

Food Chemistry International, EarlyView.
After collecting Musa paradisiaca leaves, some were dried and others were used to produce aqueous extracts. The extracts and powders were characterized and then administered to rats made anaemic by PHZ. After 14 days of administration of the two samples, the rats were euthanized and it was observed that after 9 days of treatment, the aqueous extract ...
Josée Rebeca Nombo, Jethro Roland Misse Ngangue Ekwala, Somon Régine Tuem, Stéphano Tene Tambo, Merlin Ngafon Nchoutpouen, Valery Jean François Nsoga, Jules Christophe Koule Manz, Jordan Mekui Nwotue, Mathieu Ndomou   +8 more
wiley   +1 more source

Mechanisms of functional disoreders of erythrocytes in experimental phenylhydrazine-induced methemoblobinemia

Бюллетень сибирской медицины, 2005
It was established that methemoglobiemia in experimental rats induced by one intraperitoneal injection of phenylhydrazine chloride (DL50), for a long time (up to 21 days after the injection of the drug) is accompanied by disorders in functional ...
I. A. Shprling, V. V. Novitsky, N. V. Ryazantseva, O. N. Filippova, N. M. Shevtsova, O. A. Rogov, V. V. Bas   +6 more
doaj   +1 more source

Prenatal Exome Sequencing Identifies Dual Maternal‐Fetal Diagnosis of HbF Mission Bay, a Novel HBG2 Variant Associated With Methemoglobinemia, Hypoxia and Hemolytic Anemia

Prenatal Diagnosis, EarlyView.
ABSTRACT Prenatal exome sequencing (ES) can establish rare genetic diagnoses in a fetus but may also lead to occult genetic diagnosis in a biological parent. We present a case of dual fetal and maternal diagnosis by prenatal ES, in a fetus with unexplained anemia and in a pregnant patient with sickle cell disease (SCD) and recurrent unexplained hypoxia.
Matthew A. Shear, Billie Lianoglou, Ugur Hodoglugil, W. Patrick Devine, Ashutosh Lal, Juan Gonzalez, Teresa N. Sparks   +6 more
wiley   +1 more source

Avaliação laboratorial da toxicidade molecular em eritrócitos talassêmicos Laboratorial evaluation of molecular toxicity in thalassemic erythrocytes

Revista Brasileira de Hematologia e Hemoterapia, 2006
Oxygen-derived free radical damage is associated with the molecular toxicity of hemoglobin. Especially in thalassemia syndromes, this toxicity has a relationship with "free" alpha globin concentrations.
Paulo Cesar Naoum, Sheldon S. S. Querino, Nathália M. Cury, Cristiane G. Toledo, Flávio Augusto Naoum   +4 more
doaj   +1 more source

Efek Pemberian Vitamin C Berbagai Dosis pada Profil Kadar Methemoglobin Polisi yang Bertugas di Area Lampu Lalu Lintas* [PDF]

, 2000
Sebuah penelitian telah dilakukan dengan mengajukan hipotesis bahwa terdapatpenurunan kadar methemoglobin setelah pemberian vitamin C pada polisi yang bertugas diarea lampu lalu lintas.
Syukriani, Y. F. (Yoni)
core  

Acute freshwater CO2 exposure does not impair seawater transfer in three different sizes of Atlantic salmon (Salmo salar) subjected to different photoperiod manipulations

Journal of Fish Biology, EarlyView.
Abstract There is a growing interest in Atlantic salmon (Salmo salar) aquaculture to extend the time fish are reared in freshwater (FW) recirculating aquaculture systems (RAS), producing larger FW salmon that can then be induced to undergo smoltification before transfer into marine net pens for grow‐out and harvest.
Le Thi Hong Gam, Daniel W. Montgomery, Daniel S. Laronde, Rachael Mackinnon, Jeffrey G. Richards, Colin J. Brauner   +5 more
wiley   +1 more source