Results 91 to 100 of about 3,608,507 (334)

A Photothermal‐Responsive PRP‐Loaded Hydrogel Engineered With Composite Nanobottle for Controllable Delivery of Growth Factors and Multifunctional Therapy of Diabetic Wounds

Advanced Science, EarlyView.
A photothermal‐responsive engineered platelet‐rich plasma hydrogel (CNB‐ePRP) incorporated with thrombin‐functionalized composite nanobottle was developed, which enables in situ PRP activation, on‐demand growth factor release, multifunctionality, and personalized antimicrobial loading for treatment of diabetic wounds. The CNB‐ePRP hydrogel demonstrated
Wen‐Qiang Qu, Hui‐Yun Gu, Si‐Min Zeng, Chang‐Jiang Liu, Xiao Yan, Ting Pan, Chao Jian, Xian‐Zheng Zhang, Ai‐Xi Yu   +8 more
wiley   +1 more source

Microbial Spectrum and Resistance Patterns in Ocular Infections: A 15-Year Review in East China

Infection and Drug Resistance, 2021
Chunhong Liu,1,2,* Baixing Ding,3,* Jian Ji,1 Zhujian Wang,1 Huiwen Chen,1 Wenjun Cao1,2 1Clinical Laboratory, Eye & ENT Hospital, Fudan University, Shanghai, People’s Republic of China; 2Eye Institute and Department of Ophthalmology, Eye &
Liu C, Ding B, Ji J, Wang Z, Chen H, Cao W   +5 more
doaj  

Self‐Amplifying Redox Cycle Triggers Ferroptosis/Cuproptosis Synergy for Enhanced Bacterial Eradication

Advanced Science, EarlyView.
This study designs a targeted nanocomposite (ct@HMCF‐Dex) that responds to acidic infection microenvironments, releasing components which amplify oxidative stress. It disrupts bacterial redox balance, chelates metals to sustain lipid peroxidation, and synergistically induces cuproptosis/ferroptosis‐like death.
Zehui Xiao, Shaolong Qiu, Jiangli Cao, Jifeng Liu, Zhiyong Song, Ting Du, Xinjun Du   +6 more
wiley   +1 more source

Antibiotic resistance in Staphylococcus aureus isolated from clinical samples by disk diffusion and PCR methods

مجله دانشگاه علوم پزشکی گرگان, 2016
Background and Objective: Resistance of Staphylococcus aureus to antibiotics is one of the major global health problems in human societies. Thus, evaluation of pattern of antibiotic resistance in its different strains is very important.
Kavoosinezhad F, Fattahi E, Moori Bakhtiari N   +2 more
doaj  

Methicillin- and Inducible Clindamycin-Resistant Staphylococcus aureus among Patients with Wound Infection Attending Arba Minch Hospital, South Ethiopia

International Journal of Microbiology, 2019
Background. Wound infection is one of the most common hospital-acquired infections. Different bacteria cause infection, of which Staphylococcus aureus is one of the known bacteria in causing infection with increased drug-resistant isolates. Objective. To
Mohammedaman Mama, Addis Aklilu, Kassahun Misgna, Molla Tadesse, Eyerusalem Alemayehu   +4 more
doaj   +1 more source

Hypericin enhances β-lactam antibiotics activity by inhibiting sarA expression in methicillin-resistant Staphylococcus aureus. [PDF]

, 2019
Bacteremia is a life-threating syndrome often caused by methicillin-resistant Staphylococcus aureus (MRSA). Thus, there is an urgent need to develop novel approaches to successfully treat this infection.
Jiang, Jiandong, Li, Liang, Li, Xue, Wang, Genzhu, Wang, Xiukun, Xiong, Yan Q, You, Xuefu, Yu, Jie, Zhang, Youwen   +8 more
core  

Scope and Predictive Genetic/Phenotypic Signatures of Bicarbonate (NaHCO3) Responsiveness and β-Lactam Sensitization in Methicillin-Resistant Staphylococcus aureus. [PDF]

, 2020
Addition of sodium bicarbonate (NaHCO3) to standard antimicrobial susceptibility testing medium reveals certain methicillin-resistant Staphylococcus aureus (MRSA) strains to be highly susceptible to β-lactams.
Bayer, Arnold S, Chambers, Henry F, Chen, Liang, Ersoy, Selvi C, Fowler, Vance G, Kreiswirth, Barry, Li, Liang, Mediavilla, Jose, Milan, Vanessa T, Otmishi, Mariam, Pak, Youngju, Proctor, Richard A, Xiong, Yan Q   +12 more
core   +1 more source

Impact of time to appropriate therapy on mortality in patients with vancomycin-intermediate Staphylococcus aureus infection [PDF]

, 2016
Despite the increasing incidence of vancomycin-intermediate Staphylococcus aureus (VISA) infections, few studies have examined the impact of delay in receipt of appropriate antimicrobial therapy on outcomes in VISA patients.
Burnham, Carey-Ann D, Burnham, Jason P, Kollef, Marin H, Warren, David K   +3 more
core   +2 more sources

Dual‐Mode Type I/II Photosensitization of a Stable Mesoporous Hydrogen‐Bonded Organic Framework for Antibacterial Therapy

Advanced Science, EarlyView.
A π‐conjugated donor–acceptor PDI monomer undergoes hydrogen‐bonded self‐assembly to form a robust mesoporous framework. The ordered molecular arrangement promotes efficient intersystem crossing and charge separation, leading to simultaneous Type I and Type II reactive oxygen species generation with a high singlet oxygen quantum yield.
Yi‐Lun Cheng, Hui Yuan, Yuhang Li, Zi‐Yu Wang, Rui Wang, Qi Yin, Xue‐Ning Ren, Miao Zheng, Yi Zeng, Tian‐Fu Liu, Zaisheng Ye   +10 more
wiley   +1 more source

Biofilm formation among methicillin-resistant Staphylococcus aureus isolates from patients with urinary tract infection. [PDF]

, 2004
Staphylococci have been confirmed to form biofilms on various biomaterials. The purpose of this study was to investigate biofilm formation among methicillin-resistant Staphylococcus aureus (MRSA) isolates from patients with urinary tract infection (UTI ...
Ando, Eiichi, Kariyama, Reiko, Kumon, Hiromi, Mitsuhata, Ritsuko, Monden, Koichi   +4 more
core   +1 more source