Results 71 to 80 of about 126,280 (295)

Antimicrobial Susceptibility Trends Observed in Urinary Pathogens Obtained From New York State [PDF]

, 2018
International guidelines recommend using local susceptibility data to direct empiric therapy for acute uncomplicated cystitis. We evaluated outpatient urinary isolate susceptibility trends in New York State.
Avery, Lisa M., Bankert, Eve, Carreno, Joseph J., Dobson, Erica, Dumyati, Ghinwa, Hassett, Stephen, Keller, Marina, Lodise, Thomas, Lubowski, Theresa, Pearsall, Matthew, Rank, Elliot L.   +10 more
core   +1 more source

Biofilm is a major virulence determinant in bacterial colonization of chronic skin ulcers independently from the multidrug resistant phenotype [PDF]

, 2017
Bacterial biofilm is a major factor in delayed wound healing and high levels of biofilm production have been repeatedly described in multidrug resistant organisms (MDROs).
Bordignon, Valentina, Cavallo, Ilaria, Cilli, Laura, De Santis, Alessandra, Di Domenico, Enea Gino, Di Salvo, Fabiola, Ensoli, Fabrizio, Farulla, Ilaria, Gallo, Maria Teresa, La Parola, Ilaria Lesnoni, Pimpinelli, Fulvia, Pontone, Martina, Prignano, Grazia, Sperduti, Isabella, Toma, Luigi, Vespaziani, Matteo   +15 more
core   +2 more sources

Pathogen‐Centric Activation of an Azoreductase‐Responsive Antibody‐Antibiotic Conjugate for the Targeted Eradication of MRSA

Advanced Science, EarlyView.
A pathogen‐centric antibody‐antibiotic conjugate (AZO‐AAC) releases antibiotics via bacterial azoreductase, independent of host‐lysosomal function. This mechanism achieves nanomolar eradication of both planktonic and intracellular methicillin‐resistant Staphylococcus aureus (MRSA).
Qi Cheng, Lianqi Liu, Chenghua Liu, Fei Xie, Jingwen Dong, Xiaoyu Qin, Shunxiang Huang, Xian Li, Xingyuan Kou, Hongbin Deng, Jiannan Feng, Wu Zhong, Dian Xiao, Xinbo Zhou   +13 more
wiley   +1 more source

Identification of a highly transmissible animal-independent Staphylococcus aureus ST398 clone with distinct genomic and cell adhesion properties. [PDF]

, 2012
A methicillin-resistant Staphylococcus aureus (MRSA) clone known as ST398 has emerged as a major cause of acute infections in individuals who have close contact with livestock.
Alikhan, Armand-Lefevre, Bens, Bhat, Bootsma, Castillo-Ramirez, Crombe, Cuny, DelVecchio, Devriese, Fan, Graveland, Hasman, Herron-Olson, Kaneko, Kapatral, Khanna, Leonard, Lowder, Lowy, McCarthy, McCarthy, Phillips, Rasigade, Rocha, Schijffelen, Stegger, Sung, Tatusov, Uhlemann, Uhlemann, van Belkum, van Cleef, van Loo, van Wamel, Viana, Voss, Walsh, Wassenberg, Witte   +39 more
core   +1 more source

Microblasting Wound Dressings Mechanically Disrupt Polymicrobial Biofilms to Enhance Healing in Treatment‐Resistant Wounds

Advanced Science, EarlyView.
Treatment‐resistant wounds caused by polymicrobial biofilms are refractory to conventional therapies due to the dense extracellular matrices. We developed μBLAST, a microblasting wound dressing that combines MnO2‐doped biosilica and a H2O2‐releasing mesh to generate localized oxygen microbubbles that mechanically disrupt biofilms.
Yujin Ahn, Joo Hun Lee, Christian Hurd, Jiye Lee, Junggeon Park, Adam A. Markowicz, Zheyuan Zhang, Joanne Hwang, Guillermo L. Monroy, Simon A. Rogers, Woonggyu Jung, Stephen A. Boppart, Hyunjoon Kong   +12 more
wiley   +1 more source

Antibiotic resistance in Staphylococcus aureus isolated from clinical samples by disk diffusion and PCR methods

مجله دانشگاه علوم پزشکی گرگان, 2016
Background and Objective: Resistance of Staphylococcus aureus to antibiotics is one of the major global health problems in human societies. Thus, evaluation of pattern of antibiotic resistance in its different strains is very important.
Kavoosinezhad F, Fattahi E, Moori Bakhtiari N   +2 more
doaj  

Antibacterial and anti-quorum sensing activities of selected italian honeys against antibiotic-resistant pathogens [PDF]

, 2015
Three nectar honeys (eucalyptus, thyme and forest) and two honeydew honeys (fir and Metcalfa) from Italy were tested for their antibacterial activity against pathogens commonly associated with wound and burn infections, including methicillin-resistant ...
Fidaleo, Marco, Lavecchia, Roberto, Zuorro, Antonio   +2 more
core   +1 more source

Impact of Prophylactic Cefepime on Surgical Site Infection and Severe Morbidity in Patients Who Underwent Pancreaticoduodenectomy With Preoperative Biliary Drainage

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background Although prophylactic broad‐spectrum antibiotics can reduce postoperative complications after pancreaticoduodenectomy (PD), the optimal regimen remains uncertain. This study evaluated the impact of prophylactic cefepime (CFPM) on surgical site infection (SSI) and severe morbidity after PD with preoperative biliary drainage.
Genki Watanabe, Akihiro Murata, Yu Kasamatsu, Atsushi Ishihara, Daisuke Nagashima, Tetsuzo Tashima, Shintaro Kodai, Akishige Kanazawa, Sadatoshi Shimizu   +8 more
wiley   +1 more source

Microbial Spectrum and Resistance Patterns in Ocular Infections: A 15-Year Review in East China

Infection and Drug Resistance, 2021
Chunhong Liu,1,2,* Baixing Ding,3,* Jian Ji,1 Zhujian Wang,1 Huiwen Chen,1 Wenjun Cao1,2 1Clinical Laboratory, Eye & ENT Hospital, Fudan University, Shanghai, People’s Republic of China; 2Eye Institute and Department of Ophthalmology, Eye &
Liu C, Ding B, Ji J, Wang Z, Chen H, Cao W   +5 more
doaj  

De Novo 2.2 Mb 19q13.42–q13.43 Microdeletion Encompassing U2AF2: Support for a Haploinsufficiency Model

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT U2 small nuclear RNA auxiliary factor 2 (U2AF2) is an essential pre‐mRNA splicing factor involved in the early stages of pre‐mRNA splicing. To date, multiple individuals have been reported with predominantly heterozygous missense variants presenting intellectual disability, speech and motor delays, seizures, hypotonia, and thin or hypoplastic ...
Amanda Toledo, Sarah Araji, Weimin Bi, Seema R. Lalani   +3 more
wiley   +1 more source