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Sensing and Signaling of Methionine Metabolism
Metabolites, 2021 Availability of the amino acid methionine shows remarkable effects on the physiology of individual cells and whole organisms. For example, most cancer cells, but not normal cells, are hyper dependent on high flux through metabolic pathways connected to ...
Linda Lauinger, Peter Kaiser
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Methionine Dependence of Cancer [PDF]
Biomolecules, 2020 Tumorigenesis is accompanied by the reprogramming of cellular metabolism. The shift from oxidative phosphorylation to predominantly glycolytic pathways to support rapid growth is well known and is often referred to as the Warburg effect.
P. Kaiser
semanticscholar +6 more sources
An allosteric mechanism for switching between parallel tracks in mammalian sulfur metabolism. [PDF]
PLoS Computational Biology, 2008 Methionine (Met) is an essential amino acid that is needed for the synthesis of S-adenosylmethionine (AdoMet), the major biological methylating agent.
Tatyana K Korendyaseva +6 more
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Temporal profile of amino acids and protein fractions in the developing kernel of maize germplasm [PDF]
Scientific ReportsMaize, the most important source of animal and poultry feed, is deficient in essential amino acid methionine. Therefore, methionine is added to the poultry feed to meet its nutritional requirements.
Veena Devi +5 more
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Antioxidants, 2021 Methionine is an aliphatic, sulfur-containing, essential amino acid that has been demonstrated to have crucial roles in metabolism, innate immunity, and activation of endogenous antioxidant enzymes, including methionine sulfoxide reductase A/B and the ...
Mariano Catanesi +11 more
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Gut, 2022 Objective Methionine metabolism is involved in a myriad of cellular functions, including methylation reactions and redox maintenance. Nevertheless, it remains unclear whether methionine metabolism, RNA methylation and antitumour immunity are molecularly ...
Ting Li +11 more
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Redox Report, 2023 Background Methionine sulfoxide reductases are found in all aerobic organisms. They function in antioxidant defense, cellular regulation by reversible oxidation of methionine in proteins, and in protein structure.
Sujin Park +2 more
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Label-free metabolic imaging of non-alcoholic-fatty-liver-disease (NAFLD) liver by volumetric dynamic optical coherence tomography [PDF]
Biomed. Opt. Express 13 (2022) 4071-4086, 2022 Label-free metabolic imaging of non-alcoholic fatty liver disease (NAFLD) mouse liver is demonstrated ex vivo by dynamic optical coherence tomography (OCT). The NAFLD mouse is a methionine choline-deficient (MCD)-diet model, and two mice fed MCD diet for 1 and 2 weeks are involved in addition to a normal-diet mouse.
arxiv +1 more source
Cystathionine beta synthase deficiency and brain edema associated with methionine excess under betaine supplementation: Four new cases and a review of the evidence. [PDF]
, 2020 CBS deficient individuals undergoing betaine supplementation without sufficient dietary methionine restriction can develop severe hypermethioninemia and brain edema. Brain edema has also been observed in individuals with severe hypermethioninemia without
Barea, Jaime J +10 more
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