Results 1 to 10 of about 33,008 (106)

Effect of methyl donors supplementation on performance, immune responses and anti-oxidant variables in broiler chicken fed diet without supplemental methionine [PDF]

open access: yesAnimal Bioscience, 2022
Objective Methionine (Met) is involved in methyl group transfer besides protein synthesis. As the availability is limited and cost is high for synthetic Met, reductions in its inclusion in broiler diet may be possible by supplementing the low Met diets ...
Venkata Rama Rao Savaram   +4 more
doaj   +1 more source

L-Methionine Protects against Oxidative Stress and Mitochondrial Dysfunction in an In Vitro Model of Parkinson’s Disease

open access: yesAntioxidants, 2021
Methionine is an aliphatic, sulfur-containing, essential amino acid that has been demonstrated to have crucial roles in metabolism, innate immunity, and activation of endogenous antioxidant enzymes, including methionine sulfoxide reductase A/B and the ...
Mariano Catanesi   +11 more
doaj   +1 more source

Ndufaf2, a protein in mitochondrial complex I, interacts in vivo with methionine sulfoxide reductases

open access: yesRedox Report, 2023
Background Methionine sulfoxide reductases are found in all aerobic organisms. They function in antioxidant defense, cellular regulation by reversible oxidation of methionine in proteins, and in protein structure.
Sujin Park   +2 more
doaj   +1 more source

Sensing and Signaling of Methionine Metabolism

open access: yesMetabolites, 2021
Availability of the amino acid methionine shows remarkable effects on the physiology of individual cells and whole organisms. For example, most cancer cells, but not normal cells, are hyper dependent on high flux through metabolic pathways connected to ...
Linda Lauinger, Peter Kaiser
doaj   +1 more source

Label-free metabolic imaging of non-alcoholic-fatty-liver-disease (NAFLD) liver by volumetric dynamic optical coherence tomography [PDF]

open access: yesBiomed. Opt. Express 13 (2022) 4071-4086, 2022
Label-free metabolic imaging of non-alcoholic fatty liver disease (NAFLD) mouse liver is demonstrated ex vivo by dynamic optical coherence tomography (OCT). The NAFLD mouse is a methionine choline-deficient (MCD)-diet model, and two mice fed MCD diet for 1 and 2 weeks are involved in addition to a normal-diet mouse.
arxiv   +1 more source

4006 Methionine Dependence in Cancer: From Metabolic Phenotype to Therapy

open access: yesJournal of Clinical and Translational Science, 2020
OBJECTIVES/GOALS: Methionine dependence was described 45 years ago as an increased reliance on an exogenous supply of the essential amino acid methionine in most cancer cells compared to normal cells. Methionine depletion, using either synthetic diets or
Isabelle Miousse
doaj   +1 more source

High-Throughput Metabolomics Platform for the Rapid Data-Driven Development of Novel Additive Solutions for Blood Storage

open access: yesFrontiers in Physiology, 2022
Red blood cell transfusion is a life-saving intervention, and storage is a logistic necessity to make ~110 million units available for transfusion every year worldwide. However, storage in the blood bank is associated with a progressive metabolic decline,
Travis Nemkov   +5 more
doaj   +1 more source

Roles of sulfur-containing amino acids in gastrointestinal physiology and pathophysiology [PDF]

open access: yesVojnosanitetski Pregled, 2021
nema
Todorović Dušan D.   +8 more
doaj   +1 more source

An allosteric mechanism for switching between parallel tracks in mammalian sulfur metabolism. [PDF]

open access: yesPLoS Computational Biology, 2008
Methionine (Met) is an essential amino acid that is needed for the synthesis of S-adenosylmethionine (AdoMet), the major biological methylating agent.
Tatyana K Korendyaseva   +6 more
doaj   +1 more source

Imaging Sub-Cellular Methionine and Insulin Interplay in Triple Negative Breast Cancer Lipid Droplet Metabolism

open access: yesFrontiers in Oncology, 2022
Triple negative breast cancer (TNBC) is a particularly aggressive cancer subtype that is difficult to diagnose due to its discriminating epidemiology and obscure metabolome. For the first time, 3D spatial and chemometric analyses uncover the unique lipid
Anthony A. Fung   +5 more
doaj   +1 more source

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