Results 81 to 90 of about 4,135 (162)

Leishmania donovani methionine adenosyltransferase

, 2013
This research was supported by Comisión Interministerial de Ciencia y Tecnología (grants PM98/0036 and PB96/0159), Junta de Castilla y León (grants LE05/01 and LE06/02) and Fondo de Investigación Sanitaria del Ministerio de Sanidad y Consumo (grant FIS 01/1077).
Pérez-Pertejo, Yolanda, Pajares, María Ángeles, Ordóñez, David   +2 more
openaire   +1 more source

mTORC1-independent translation control in mammalian cells by methionine adenosyltransferase 2A and S-adenosylmethionine. [PDF]

J Biol Chem, 2022
Alam M, Shima H, Matsuo Y, Long NC, Matsumoto M, Ishii Y, Sato N, Sugiyama T, Nobuta R, Hashimoto S, Liu L, Kaneko MK, Kato Y, Inada T, Igarashi K.   +14 more
europepmc   +1 more source

Polar Interactions at the Dimer-Dimer Interface of Methionine Adenosyltransferase MAT I Control Tetramerization. [PDF]

Int J Mol Sci, 2021
Sánchez-Pérez GF, Pajares MÁ.
europepmc   +1 more source

MAT2B expression correlates with poor prognosis in triple-negative breast cancer

Cancer Management and Research, 2019
Jin Xu,1 Di Wu,2 Siliang Wang,3 Zhe Wang41Department of Surgery, Shengjing Hospital of China Medical University, Shenyang 110004, People’s Republic of China; 2Department of Tumor Biotherapy and Cancer Research, The First Affiliated Hospital of ...
Xu J, Wu D, Wang S, Wang Z
doaj  

Epigenome-wide impact of MAT2A sustains the androgen-indifferent state and confers synthetic vulnerability in ERG fusion-positive prostate cancer

Nature Communications
Castration-resistant prostate cancer (CRPC) is a frequently occurring disease with adverse clinical outcomes and limited therapeutic options. Here, we identify methionine adenosyltransferase 2a (MAT2A) as a critical driver of the androgen-indifferent ...
Alessia Cacciatore, Dheeraj Shinde, Carola Musumeci, Giada Sandrini, Luca Guarrera, Domenico Albino, Gianluca Civenni, Elisa Storelli, Simone Mosole, Elisa Federici, Alessio Fusina, Marta Iozzo, Andrea Rinaldi, Matteo Pecoraro, Roger Geiger, Marco Bolis, Carlo V. Catapano, Giuseppina M. Carbone   +17 more
doaj   +1 more source

Deregulated 14-3-3ζ and methionine adenosyltransferase α1 interplay promotes liver cancer tumorigenesis in mice and humans. [PDF]

Oncogene, 2021
Lu L, Zhang J, Fan W, Li Y, Wang J, Li TWH, Barbier-Torres L, Mato JM, Liu T, Seki E, Matsuda M, Tomasi ML, Bhowmick NA, Yang H, Lu SC.   +14 more
europepmc   +1 more source

Activating transcription factor 4 regulates angiogenesis under lipid overload via methionine adenosyltransferase 2A-mediated endothelial epigenetic alteration. [PDF]

FASEB J, 2021
Chen L, Liu X, Zhou H, Li G, Huang F, Zhang J, Xia T, Lei W, Zhao J, Li C, Chen M.   +10 more
europepmc   +1 more source

Methionine Adenosyltransferase Deficiency [PDF]

, 2020
openaire   +1 more source

Unfolded protein response kinase PERK supports survival and metastasis of circulating tumor cell clusters via SAM synthesis and H3K4me3‐dependent PDGFB signaling

Cancer Communications
Background Metastasis is the leading cause of cancer‐related mortality, with circulating tumor cell (CTC) clusters serving as highly efficient precursors of distant metastasis.
Rui Tang, Yan Sun, Ao Deng, Jiahe Liu, Peijin Dai, Jing Chen, Chaoqun Deng, Hui Liu, Yuhang Hai, Yanran Tong, Yan‐e Du, Manran Liu, Haojun Luo   +12 more
doaj   +1 more source

Methionine Adenosyltransferase Engineering to Enable Bioorthogonal Platforms for AdoMet-Utilizing Enzymes. [PDF]

ACS Chem Biol, 2020
Huber TD, Clinger JA, Liu Y, Xu W, Miller MD, Phillips GN, Thorson JS.   +6 more
europepmc   +1 more source