Results 1 to 10 of about 60,211 (294)

Associations of S-Adenosylmethionine and S-Adenosylhomocysteine with Hepatocellular Carcinoma [PDF]

Metabolites
Background: Hepatocellular carcinoma (HCC) is a leading cause of cancer-related deaths worldwide, increasingly arising in patients with metabolic dysfunction-associated steatotic liver disease (MASLD).
Naana N. Yalley, Sebastian M. Armasu, Winnie Z. Fan, Irene K. Yan, Fowsiyo Y. Ahmed, Per Stål, Lewis R. Roberts, Tushar Patel, Samuel O. Antwi   +8 more
doaj   +2 more sources

Interplay of serum taurine, S-adenosylmethionine, and cysteine levels in cancer risk: a prospective study [PDF]

Frontiers in Pharmacology
BackgroundAmino acids are known to play critical roles in cancer metabolism and progression. Among them, taurine, S-adenosylmethionine (SAM), and cysteine have garnered particular attention due to their interconnected metabolic pathways.
Chenan Liu, Chenan Liu, Chenan Liu, Chenan Liu, Chenan Liu, Tong Liu, Tong Liu, Tong Liu, Tong Liu, Tong Liu, Yaping Wei, Jinyu Shi, Jinyu Shi, Jinyu Shi, Jinyu Shi, Jinyu Shi, Li Deng, Li Deng, Li Deng, Mengmeng Song, Hanping Shi, Hanping Shi, Hanping Shi, Hanping Shi, Hanping Shi   +24 more
doaj   +2 more sources

(S)–S-adenosylmethionine in the treatment of pre-menstrual disorders in adult women: A protocol for an open-label pilot study [PDF]

Contemporary Clinical Trials Communications
Pre-menstrual disorders, including pre-menstrual syndrome and pre-menstrual dysphoric disorder, are highly prevalent disorders in women of reproductive age. Pre-menstrual disorders are associated with debilitating symptoms that onset in the days prior to
Brendan Stevenson, Emorfia Gavrilidis, Yasmin Malik, Jayashri Kulkarni   +3 more
doaj   +2 more sources

Engineered reduction of S-adenosylmethionine alters lignin in sorghum [PDF]

Biotechnology for Biofuels and Bioproducts
Background Lignin is an aromatic polymer deposited in secondary cell walls of higher plants to provide strength, rigidity, and hydrophobicity to vascular tissues.
Yang Tian, Yu Gao, Halbay Turumtay, Emine Akyuz Turumtay, Yen Ning Chai, Hemant Choudhary, Joon-Hyun Park, Chuan-Yin Wu, Christopher M. De Ben, Jutta Dalton, Katherine B. Louie, Thomas Harwood, Dylan Chin, Khanh M. Vuu, Benjamin P. Bowen, Patrick M. Shih, Edward E. K. Baidoo, Trent R. Northen, Blake A. Simmons, Robert Hutmacher, Jackie Atim, Daniel H. Putnam, Corinne D. Scown, Jenny C. Mortimer, Henrik V. Scheller, Aymerick Eudes   +25 more
doaj   +2 more sources

S‐adenosylmethionine and nicotinamide riboside therapy in Arts syndrome: A case report and literature review [PDF]

JIMD Reports, 2023
Phospho‐ribosyl‐pyrophosphate synthetase 1 (PRPS1) deficiency is secondary to loss of function variants in PRPS1. This enzyme generates phospho‐ribosyl‐pyrophosphate (PRPP), which is utilized in the synthesis of purines, nicotinamide adenine dinucleotide
Angela Lee, Renatta Knox, Margaret Reynolds, Erin McRoy, Hoanh Nguyen   +4 more
doaj   +2 more sources

Cysteine Restriction Induces Ferroptosis Depending on the S-adenosylmethionine and Polyamine Biosynthetic Pathways in Hepatic Cancer Cells [PDF]

Gastro Hep Advances
Background and Aims: Liver diseases such as hepatocellular carcinoma are known to be affected by nutrition and metabolic activities, but the mechanisms behind them remain unclear.
Keisuke Tada, Kazuki Mitsuyama, Hironari Nishizawa, Hiroki Shima, Akihiko Muto, Motoshi Wada, Daisuke Saigusa, Kazuhiko Igarashi   +7 more
doaj   +2 more sources

Impact of sevoflurane anesthesia on S-adenosylmethionine in neonates under general anesthesia [PDF]

Journal of Anaesthesiology Clinical Pharmacology
Background and Aims: Preclinical studies in rodents and primates have shown that anesthesia was neurotoxic to the developing brain after exposure in the neonatal period. Sevoflurane a commonly used inhalational anesthetic, especially in pediatric surgery,
Saraswathi Nagappa, Sandhya Kalappa, Raghavendra B. Sridhara, Dayananda S. Biligi, R Annapoorneshwari, Ramachandraiah   +5 more
doaj   +2 more sources

Aurora kinase A promotes trained immunity via regulation of endogenous S-adenosylmethionine metabolism. [PDF]

Elife
Li M, Jin H, Liu Y, Wang Z, Li L, Wang T, Wang X, Zhang H, Huo B, Yu T, Wang S, Zhao W, Liu J, Huang P, Cui J, Xia X.   +15 more
europepmc   +3 more sources

Dual Stabilization of S‑Adenosylmethionine for Enzymatic DNA Labeling [PDF]

JACS Au
Jonas Bucevičius, Ru̅ta Gerasimaitė, Gražvydas Lukinavičius   +2 more
doaj   +2 more sources

Hepatic levels of S-adenosylmethionine regulate the adaptive response to fasting

Cell Metabolism, 2023
David Fernández-Ramos, Naroa Goikoetxea-Usandizaga, Marina Serrano-Maciá   +2 more
exaly   +2 more sources