Results 21 to 30 of about 43,956,264 (204)
bioRxiv, 2020 SARS-CoV-2 is a member of the coronaviridae family and is the etiological agent of the respiratory Coronavirus Disease 2019. The virus has spread rapidly around the world resulting in over two million cases and nearly 150,000 deaths as of April 17, 2020.
M. Rosas-Lemus +13 more
semanticscholar +1 more source
SAMTOR is an S-adenosylmethionine sensor for the mTORC1 pathway
Science, 2017 SAMTOR joins the family The amino acid methionine is widely appreciated to have interesting effects on animal physiology. Diets low in methionine increase longevity and overall health, particularly glucose homeostasis. Gu et al.
X. Gu +9 more
semanticscholar +1 more source
Ademethionine in the treatment of fatigue in liver diseases: a systematic review [PDF]
Терапевтический архив, 2019 Fatigue has a significant effect on the condition of patients with liver disease. Ademethionine is considered one of the most promising drugs for its treatment. Aim.
K L Raikhelson, E A Kondrashina
doaj +1 more source
S-adenosylmethionine metabolism and liver disease
Annals of Hepatology, 2013 Methionine is an essential amino acid that is metabolized mainly by the liver where it is converted to S-adenosylmethionine (SAMe) by the enzyme methionine adenosyltransferase.
José M. Mato +2 more
doaj +1 more source
Molecules and Cells, 2019 Activated macrophages adapt their metabolic pathways to drive the pro-inflammatory phenotype, but little is known about the biochemical underpinnings of this process.
Weiwei Yu +11 more
semanticscholar +1 more source
Natural history of S-adenosylmethionine-binding proteins [PDF]
, 2005 BACKGROUND:S-adenosylmethionine is a source of diverse chemical groups used in biosynthesis and modification of virtually every class of biomolecules. The most notable reaction requiring S-adenosylmethionine, transfer of methyl group, is performed by a ...
Piotr Z Kozbial +4 more
core +2 more sources
PLoS Pathogens, 2011 Cellular and viral S-adenosylmethionine-dependent methyltransferases are involved in many regulated processes such as metabolism, detoxification, signal transduction, chromatin remodeling, nucleic acid processing, and mRNA capping.
Etienne Decroly +12 more
doaj +1 more source
Structural Basis for Regulation of METTL16, an S-Adenosylmethionine Homeostasis Factor
Molecules and Cells, 2018 SUMMARY S-adenosylmethionine (SAM) is an essential metabolite that acts as a cofactor for most methylation events in the cell. The N6-methyladenosine (m6A) methyltransferase METTL16 controls SAM homeostasis by regulating the abundance of SAM synthetase ...
K. Doxtader +5 more
semanticscholar +1 more source
International Journal of Biological Macromolecules, 2020 S-adenosylmethionine synthases (MATs) are responsible for production of S-adenosylmethionine, the cofactor essential for various methylation reactions, production of polyamines and phytohormone ethylene, etc. Plants have two distinct MAT types (I and II).
B. Sekuła, M. Ruszkowski, Z. Dauter
semanticscholar +1 more source
环境与职业医学, 2023 BackgroundArsenic exposure can lead to liver dysfunction, liver steatosis, hepatitis, liver fibrosis, and other liver injuries, but its mechanism is still unclear and effective treatment methods are lacking.ObjectiveTo investigate the potential ...
Lu MA +5 more
doaj +1 more source