Results 21 to 30 of about 15,844,621 (256)
Dual Stabilization of S‑Adenosylmethionine for Enzymatic DNA Labeling [PDF]
JACS AuJonas Bucevičius +2 more
doaj +2 more sources
Redox Biology, 2020 Acute pancreatitis is an inflammatory process of the pancreatic gland that may lead to dysregulation of the trans-sulfuration pathway. The aims of this work were firstly to study the methionine cycle as well as the trans-sulfuration pathway using ...
Sergio Rius-Pérez +11 more
doaj +1 more source
S-Adenosylmethionine and Pneumocystis [PDF]
FEMS Microbiology Letters, 2004 Pneumocystis is a parasitic fungus causing pneumonia in immunosuppressed mammals and S-adenosylmethionine a key intermediary metabolite for all cells. Other than a species of Rickettsia bacteria and an aberrant strain of the protozoan Amoeba proteus, Pneumocystis is the only cell known unable to synthesize AdoMet; it must extract this key compound from
Salim, Merali, Allen Boykin, Clarkson
openaire +2 more sources
Stable Isotope Dilution Assays for Clinical Analyses of Folates and Other One-Carbon Metabolites: Application to Folate-Deficiency Studies. [PDF]
PLoS ONE, 2016 Folate deficiency is generally accepted as a potential direct or indirect risk factor for diseases including spina bifida, coronary heart diseases, malfunctions of the central nervous system, and cancer. The direct inclusion of folates in the methylation
Markus Kopp +3 more
doaj +1 more source
Hepatic levels of S-adenosylmethionine regulate the adaptive response to fasting
Cell Metabolism, 2023 CARLOS Matute +2 more
exaly +2 more sources
5-methyl-tetrahydrofolate and the S-adenosylmethionine cycle in C57BL/6J mouse tissues: gender differences and effects of arylamine N-acetyltransferase-1 deletion. [PDF]
PLoS ONE, 2013 Folate catabolism involves cleavage of the C(9)-N(10) bond to form p-aminobenzoylgluamate (PABG) and pterin. PABG is then acetylated by human arylamine N-acetyltransferase 1 (NAT1) before excretion in the urine.
Katey L Witham +5 more
doaj +1 more source
Metabolites, 2022 S-adenosylmethionine (SAM) is essential for methyl transfer reactions. All SAM is produced de novo via the methionine cycle. The demethylation of SAM produces S-adenosylhomocysteine (SAH), an inhibitor of methyltransferases and the precursor of ...
Aida Corrillero Bravo +12 more
doaj +1 more source
S-Adenosylmethionine and Pneumocystis carinii [PDF]
Journal of Biological Chemistry, 2000 We previously reported that S-adenosylmethionine (AdoMet), a key molecule in methylation reactions and polyamine biosynthesis, enhances axenic culture of the AIDS-associated opportunistic fungal pathogen Pneumocystis carinii. Here we report that AdoMet is absolutely required for continuous growth. Two transporters are present, one high affinity, K(m) =
S, Merali +3 more
openaire +2 more sources
ACCUMULATION OF S-ADENOSYLMETHIONINE BY MICROORGANISMS [PDF]
Journal of Bacteriology, 1962 Gawel , L. J. (Oregon State University, Corvallis), J. R. Turner, and L. W. Parks . Accumulation of S-adenosylmethionine by microorganisms. J. Bacteriol. 83: 497–499. 1962.—A series of microorganisms selected to represent a variety of microbial types was cultured under conditions ...
L J, GAWEL, J R, TURNER, L W, PARKS
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Proteogenomic characterization of cholangiocarcinoma
Hepatology, EarlyView., 2022 Proteogenomic characterization of cholangiocarcinoma with therapeutic strategies Abstract Background and Aims Cholangiocarcinoma (CCA) is a highly heterogeneous cancer with limited understanding and few effective therapeutic approaches. We aimed at providing a proteogenomic CCA characterization to inform biological processes and treatment ...
Mengjie Deng +18 more
wiley +1 more source