Results 21 to 30 of about 60,211 (294)

Site of Prenylation Reaction in Synthesis of Phylloquinone (Vitamin K1) by Spinach Chloroplasts [PDF]

, 1981
In spinach chloroplasts, 1,4-dihydroxy-2-naphthoate is prenylated by phytyldiphosphate and subsequently methylated by S-adenosylmethionine to form phylloquinol.
Baldwin, Block, Bryant, Dialameh, Douce, Haas, Hutson, Jensen, Joo, Lee, Lichtenthaler, Lichtenthaler, Martius, Mayer, Rüdiger, Shineberg, Soil, Soll, Soll, Suttie, Thomas, Young, Zenk   +22 more
core   +1 more source

S-Adenosylmethionine Synthetase Is Required for Cell Growth, Maintenance of G0 Phase, and Termination of Quiescence in Fission Yeast

iScience, 2018
Summary: S-adenosylmethionine is an important compound, because it serves as the methyl donor in most methyl transfer reactions, including methylation of proteins, nucleic acids, and lipids.
Takeshi Hayashi, Takayuki Teruya, Romanas Chaleckis, Susumu Morigasaki, Mitsuhiro Yanagida   +4 more
doaj   +1 more source

S-adenosyl-l-methionine: (S) -7,8,13, 14-tetrahydroberberine--n-methyltransferase, a branch point enzyme in the biosynthesis of benzophenanthridine and protopine alkaloids. [PDF]

, 1986
The enzyme which transfers the CH3-group of S-adenosylmethionine to the nitrogen atom of (S)-tetrahydroberberine and (S)-stylopine is found to occur in a number of plant cell cultures originating from species containing alkaloids; it is located at an ...
Amann, Battersby, M Rueffer, M.H Zenk, Rueffer, Rueffer, Slavik, Takao, Takao   +8 more
core   +1 more source

NO sensitizes rat hepatocytes to proliferation by modifying S-adenosylmethionine levels [PDF]

, 2002
BACKGROUND & AIMS: Liver regeneration is a fundamental response of this organ to injury. Hepatocyte proliferation is triggered by growth factors, such as hepatocyte growth factor. However, hepatocytes need to be primed to react to mitogenic signals.
Avila, M.A. (Matías Antonio), Latasa, M.U. (María Ujué), Martinez-Chantar, M.L. (María Luz), Mato, J.M. (José María), Ruiz Garcia-Trevijano, E. (Elena)   +4 more
core   +1 more source

Proteogenomic characterization of cholangiocarcinoma

Hepatology, EarlyView., 2022
Proteogenomic characterization of cholangiocarcinoma with therapeutic strategies Abstract Background and Aims Cholangiocarcinoma (CCA) is a highly heterogeneous cancer with limited understanding and few effective therapeutic approaches. We aimed at providing a proteogenomic CCA characterization to inform biological processes and treatment ...
Mengjie Deng, Peng Ran, Lingli Chen, Yunzhi Wang, Zixiang Yu, Ke Cai, Jinwen Feng, Zhaoyu Qin, Yanan Yin, Subei Tan, Yang Liu, Chen Xu, Guoming Shi, Yuan Ji, Jian‐Yuan Zhao, Jian Zhou, Jia Fan, Yingyong Hou, Chen Ding   +18 more
wiley   +1 more source

S-adenosylmethionine metabolism and liver disease

Annals of Hepatology, 2013
Methionine is an essential amino acid that is metabolized mainly by the liver where it is converted to S-adenosylmethionine (SAMe) by the enzyme methionine adenosyltransferase.
José M. Mato, M. Luz Martínez-Chantar, Shelly C. Lu   +2 more
doaj   +1 more source

MTHFD1 controls DNA methylation in Arabidopsis. [PDF]

, 2016
DNA methylation is an epigenetic mechanism that has important functions in transcriptional silencing and is associated with repressive histone methylation (H3K9me).
Bischof, Sylvain, Cokus, Shawn J, Díaz de la Garza, Rocío I, Feng, Suhua, Garcia-Salinas, Carolina, Groth, Martin, Hale, Christopher J, Hell, Ruediger, Jacobsen, Steven E, John, Amala, Long, Jeff A, Moissiard, Guillaume, Ramos-Parra, Perla A, Smith, Danielle C, Wang, Haifeng, Wirtz, Markus, Zhai, Jixian   +16 more
core   +2 more sources

Mapping an atlas of tissue-specific drosophila melanogaster metabolomes by high resolution mass spectrometry [PDF]

, 2013
Metabolomics can provide exciting insights into organismal function, but most work on simple models has focussed on the whole organism metabolome, so missing the contributions of individual tissues.
A Kamleh, A Malmendal, A Malmendal, AA Jackson, C Jeulin, David G. Watson, DG Watson, DJ Creek, Dominika Korzekwa, DT Sullivan, G Di Paolo, G Fraenkel, GJ Blomquist, GX Quan, H Colinet, J Andrews, J Overgaard, Jacob Guy Bundy, JD Feala, JE Treherne, JL Hubby, JS Park, Julian A. T. Dow, KS Pedersen, L Coquin, L Pan, L Zheng, M Carvalho, M Parisi, M Rera, MA Kamleh, MA Kamleh, MF Wolfner, MM Green, Mohammed Al Bratty, MS Elias, N Vereshchagina, NE Braverman, P Niewiadomska, PA Robitaille, PS Shekhawat, R Tearle, S Buch, S Reisse, V Kostal, Venkateswara R. Chintapalli, VR Chintapalli, VR Chintapalli   +47 more
core   +6 more sources

Crystal structure and functional analysis of the SARS-coronavirus RNA cap 2'-O-methyltransferase nsp10/nsp16 complex.

PLoS Pathogens, 2011
Cellular and viral S-adenosylmethionine-dependent methyltransferases are involved in many regulated processes such as metabolism, detoxification, signal transduction, chromatin remodeling, nucleic acid processing, and mRNA capping.
Etienne Decroly, Claire Debarnot, François Ferron, Mickael Bouvet, Bruno Coutard, Isabelle Imbert, Laure Gluais, Nicolas Papageorgiou, Andrew Sharff, Gérard Bricogne, Miguel Ortiz-Lombardia, Julien Lescar, Bruno Canard   +12 more
doaj   +1 more source

Ademethionine in the treatment of fatigue in liver diseases: a systematic review [PDF]

Терапевтический архив, 2019
Fatigue has a significant effect on the condition of patients with liver disease. Ademethionine is considered one of the most promising drugs for its treatment. Aim.
K L Raikhelson, E A Kondrashina
doaj   +1 more source