Results 21 to 30 of about 21,123,172 (247)
, 1989 Methylation studies of MBP and synthetic peptides by S-adenosylmethionine-MBP methyltransferase from bovine ...
Frida. Grynspan (7963835)
core +6 more sources
S-Adenosylmethionine and Pneumocystis [PDF]
FEMS Microbiology Letters, 2004 Pneumocystis is a parasitic fungus causing pneumonia in immunosuppressed mammals and S-adenosylmethionine a key intermediary metabolite for all cells. Other than a species of Rickettsia bacteria and an aberrant strain of the protozoan Amoeba proteus, Pneumocystis is the only cell known unable to synthesize AdoMet; it must extract this key compound from
Salim, Merali, Allen Boykin, Clarkson
openaire +2 more sources
Redox Biology, 2020 Acute pancreatitis is an inflammatory process of the pancreatic gland that may lead to dysregulation of the trans-sulfuration pathway. The aims of this work were firstly to study the methionine cycle as well as the trans-sulfuration pathway using ...
Sergio Rius-Pérez +11 more
doaj +1 more source
Proteogenomic characterization of cholangiocarcinoma
Hepatology, EarlyView., 2022 Proteogenomic characterization of cholangiocarcinoma with therapeutic strategies Abstract Background and Aims Cholangiocarcinoma (CCA) is a highly heterogeneous cancer with limited understanding and few effective therapeutic approaches. We aimed at providing a proteogenomic CCA characterization to inform biological processes and treatment ...
Mengjie Deng +18 more
wiley +1 more source
S-Adenosylmethionine and Pneumocystis carinii [PDF]
Journal of Biological Chemistry, 2000 We previously reported that S-adenosylmethionine (AdoMet), a key molecule in methylation reactions and polyamine biosynthesis, enhances axenic culture of the AIDS-associated opportunistic fungal pathogen Pneumocystis carinii. Here we report that AdoMet is absolutely required for continuous growth. Two transporters are present, one high affinity, K(m) =
S, Merali +3 more
openaire +2 more sources
环境与职业医学, 2023 BackgroundArsenic exposure can lead to liver dysfunction, liver steatosis, hepatitis, liver fibrosis, and other liver injuries, but its mechanism is still unclear and effective treatment methods are lacking.ObjectiveTo investigate the potential ...
Lu MA +5 more
doaj +1 more source
Natural history of S-adenosylmethionine-binding proteins [PDF]
, 2005 BACKGROUND:S-adenosylmethionine is a source of diverse chemical groups used in biosynthesis and modification of virtually every class of biomolecules. The most notable reaction requiring S-adenosylmethionine, transfer of methyl group, is performed by a ...
Piotr Z Kozbial +4 more
core +2 more sources
mSystems, 2019 To further our understanding of one-carbon metabolism in the protozoan parasite Leishmania, we conducted genomic screens to study how the parasite responded to sinefungin (SNF) selection.
Arijit Bhattacharya +5 more
doaj +1 more source
Daropeptide natural products [PDF]
Exploration of Drug ScienceCyclophane-containing peptides comprise an important group of macrocyclic peptides with unique structural properties and pharmaceutical relevance. Darobactin A is a ribosomally synthesized and post-translationally modified peptide (RiPP) antibiotic ...
Suze Ma, Sijia Guo, Wei Ding, Qi Zhang
doaj +1 more source
A natural riboswitch scaffold with self-methylation activity
Nature Communications, 2021 In humans, protein methyltransferase is responsible for RNA methylation using S-adenosylmethionine as a methyl group donor. Here the authors report a self-methylation activity of a bacterial riboswitch.
Laurin Flemmich +4 more
doaj +1 more source