Results 31 to 40 of about 15,844,621 (256)
iScience, 2018 Summary: S-adenosylmethionine is an important compound, because it serves as the methyl donor in most methyl transfer reactions, including methylation of proteins, nucleic acids, and lipids.
Takeshi Hayashi +4 more
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S-adenosylmethionine treatment prevents carbon tetrachloride-induced S- adenosylmethionine synthetase inactivation and attenuates liver injury [PDF]
, 2013 Administration of carbon tetrachloride to rats resulted in induction of hepatic fibrosis and a 60% reduction of hepatic S-adenosylmethionine synthetase activity without producing any significant modification of hepatic levels of S-adenosylmethionine ...
Pajares, María Ángeles +3 more
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S-Adenosylmethionine in a Neuroblastoma [PDF]
Pediatric Research, 1971 Soluble extracts of a neuroblastoma did not require additional methyl donor, S-adenosyl-L-methionine (SAM), for maximal catechol O-methltransferase activity. Prior dialysis of the extract resulted in complete loss of enzymatic activity which could be partially recovered by addition of SAM to the reaction mixture.
openaire +2 more sources
S-adenosylmethionine metabolism and liver disease
Annals of Hepatology, 2013 Methionine is an essential amino acid that is metabolized mainly by the liver where it is converted to S-adenosylmethionine (SAMe) by the enzyme methionine adenosyltransferase.
José M. Mato +2 more
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Regulation of mammalian S-adenosylmethionine decarboxylase [PDF]
, 1988 S-Adenosylmethionine decarboxylase is a key enzyme in the biosynthesis of polyamines that is the rate limiting step in the formation of spermidine and spermine.
Pajunen, Antti +5 more
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PLoS Pathogens, 2011 Cellular and viral S-adenosylmethionine-dependent methyltransferases are involved in many regulated processes such as metabolism, detoxification, signal transduction, chromatin remodeling, nucleic acid processing, and mRNA capping.
Etienne Decroly +12 more
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Natural history of S-adenosylmethionine-binding proteins [PDF]
, 2005 BACKGROUND:S-adenosylmethionine is a source of diverse chemical groups used in biosynthesis and modification of virtually every class of biomolecules. The most notable reaction requiring S-adenosylmethionine, transfer of methyl group, is performed by a ...
Piotr Z Kozbial +4 more
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Ademethionine in the treatment of fatigue in liver diseases: a systematic review [PDF]
Терапевтический архив, 2019 Fatigue has a significant effect on the condition of patients with liver disease. Ademethionine is considered one of the most promising drugs for its treatment. Aim.
K L Raikhelson, E A Kondrashina
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S-adenosylmethionine administration inhibits levodopa-induced vascular endothelial growth factor-A expression [PDF]
, 2020 Studies have demonstrated that S-adenosylmethionine could effectively affect the clinical wearing-off phenomena of levodopa, an antiparkinsonian agent; however, the detailed mechanisms for this effect need to be further clarified.
Qian, Long +7 more
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S-Adenosylmethionine decarboxylase degradation by the 26 S proteasome is accelerated by substrate-mediated transamination [PDF]
, 2004 The short-lived enzyme S-adenosylmethionine decarboxylase uses a covalently bound pyruvoyl cofactor to catalyze the formation of decarboxylated S-adenosylmethionine, which then donates an aminopropyl group for polyamine biosynthesis.
Stanley, Bruce A, YERLİKAYA, AZMİ
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