Results 51 to 60 of about 43,956,264 (204)

THE ISOLATION, PURIFICATION AND KINETIC CHARACTERIZATION OF S-ADENOSYLMETHIONINE - MYELIN BASIC PROTEIN METHYLTRANSFERASE FROM BOVINE BRAIN.

, 1984
THE ISOLATION, PURIFICATION AND KINETIC CHARACTERIZATION OF S-ADENOSYLMETHIONINE - MYELIN BASIC PROTEIN METHYLTRANSFERASE FROM BOVINE ...
CYNTHIA MARIE. WAICKUS (7996004)
core   +4 more sources

METABOLISM OF S-ADENOSYLMETHIONINE IN SACCHAROMYCES CEREVISIAE DURING ASCOSPORE GERMINATION AND OUTGROWTH.

, 1976
METABOLISM OF S-ADENOSYLMETHIONINE IN SACCHAROMYCES CEREVISIAE DURING ASCOSPORE GERMINATION AND ...
SUN-JIN. CHOIH (7980731)
core   +3 more sources

(S)–S-adenosylmethionine in the treatment of pre-menstrual disorders in adult women: A protocol for an open-label pilot study

Contemporary Clinical Trials Communications
Pre-menstrual disorders, including pre-menstrual syndrome and pre-menstrual dysphoric disorder, are highly prevalent disorders in women of reproductive age. Pre-menstrual disorders are associated with debilitating symptoms that onset in the days prior to
Brendan Stevenson, Emorfia Gavrilidis, Yasmin Malik, Jayashri Kulkarni   +3 more
doaj   +1 more source

Dithiothreitol causes toxicity in C. elegans by modulating the methionine–homocysteine cycle

eLife, 2022
The redox reagent dithiothreitol (DTT) causes stress in the endoplasmic reticulum (ER) by disrupting its oxidative protein folding environment, which results in the accumulation and misfolding of the newly synthesized proteins. DTT may potentially impact
Gokul G, Jogender Singh
doaj   +1 more source

Harnessing Methylselenol (CH3SeH): A Highly Effective Platform for Stimuli‐Responsive Delivery With Therapeutic Potential

Advanced Science, EarlyView.
Tools for controlled selenol delivery are crucial for exploring Se‐related biology and medicine, but compound platforms for triggerable release of CH3SeH remain lacking. Herein, we report the first general triggered platform (TD‐MSe) for efficient cyclization release of CH3SeH in live cells.
Wenfang Liang, Liyue Wang, Xuan Wang, Xinran Li, Hao Xing, Lu Sun, Zhen Xi, Long Yi   +7 more
wiley   +1 more source

Methionine adenosyltransferase 1a antisense oligonucleotides activate the liver-brown adipose tissue axis preventing obesity and associated hepatosteatosis

Nature Communications, 2022
High methionine and S-adenosylmethionine serum levels are related with obesity. Here the authors show that knockdown of methionine adenosyltransferase by using antisense oligonucleotides provides beneficial effects in obesity and comorbidities.
Diego Sáenz de Urturi, Xabier Buqué, Begoña Porteiro, Cintia Folgueira, Alfonso Mora, Teresa C. Delgado, Endika Prieto-Fernández, Paula Olaizola, Beatriz Gómez-Santos, Maider Apodaka-Biguri, Francisco González-Romero, Ane Nieva-Zuluaga, Mikel Ruiz de Gauna, Naroa Goikoetxea-Usandizaga, Juan Luis García-Rodríguez, Virginia Gutierrez de Juan, Igor Aurrekoetxea, Valle Montalvo-Romeral, Eva M. Novoa, Idoia Martín-Guerrero, Marta Varela-Rey, Sanjay Bhanot, Richard Lee, Jesus M. Banales, Wing-Kin Syn, Guadalupe Sabio, María L. Martínez-Chantar, Rubén Nogueiras, Patricia Aspichueta   +28 more
doaj   +1 more source

Arsenic methylation by a novel ArsM As(III) S-adenosylmethionine methyltransferase that requires only two conserved cysteine residues

Molecular Microbiology, 2017
Arsenic (As) biomethylation is an important component of the As biogeochemical cycle that can influence As toxicity and mobility in the environment. Biomethylation of As is catalyzed by the enzyme arsenite (As[III]) S‐adenosylmethionine methyltransferase
Ke-he Huang, Yan Xu, C. Packianathan, Fan Gao, Chuan Chen, Jun Zhang, Q. Shen, B. Rosen, Fang-Jie Zhao   +8 more
semanticscholar   +1 more source

PHGDH‐Mediated Serine Metabolism in Nucleus Pulposus Cells Is a Potential Therapeutic Target for Intervertebral Disc Degeneration

Advanced Science, EarlyView.
When nucleus pulposus cells senesce, PHGDH decreases, reducing serine synthesis and glutathione, impairing antioxidant capacity. The intermediate α‐KG also drops, lowering JMJD3 demethylase activity, increasing H3K27me3 at the Rap1b promoter, and reducing Rap1b expression, whose down‐regulation in turn activates mTORC1 and suppresses autophagy ...
Hao‐Wei Xu, Sheng‐Jie Chang, Xiao‐Wei Liu, Shu‐Bao Zhang, Ying‐Jie Wang, Shan‐Jin Wang   +5 more
wiley   +1 more source

Vitamin B12 impacts amyloid-β induced proteotoxicity by regulating the methionine/S-adenosylmethionine cycle

, 2021
Original, unprocessed data for Lam, A.B., Kervin, K., and Tanis, J.E. (2021) Vitamin B12 impacts amyloid-β induced proteotoxicity by regulating the methionine/S-adenosylmethionine ...
Tanis, J (via Mendeley Data), Tanis, Jessica   +1 more
core   +1 more source

S‐adenosylmethionine and nicotinamide riboside therapy in Arts syndrome: A case report and literature review

JIMD Reports, 2023
Phospho‐ribosyl‐pyrophosphate synthetase 1 (PRPS1) deficiency is secondary to loss of function variants in PRPS1. This enzyme generates phospho‐ribosyl‐pyrophosphate (PRPP), which is utilized in the synthesis of purines, nicotinamide adenine dinucleotide
Angela Lee, Renatta Knox, Margaret Reynolds, Erin McRoy, Hoanh Nguyen   +4 more
doaj   +1 more source