Results 71 to 80 of about 43,956,264 (204)

Disturbance from restoration reseeding is associated with short‐term topsoil carbon loss and alters soil bacterial communities and functions in degraded alpine meadows of the Qinghai–Xizang Plateau

Grassland Research, EarlyView.
Restoration reseeding of degraded alpine meadows increased aboveground vegetation but was associated with short‐term topsoil carbon loss, coinciding with a microbial strategy shift from resident carbon‐preserving to carbon‐spending bacterial guilds. Abstract Background Restoration of degraded ecosystems is widely promoted as a nature‐based solution ...
Long‐Tao Zhu, Wen‐Min Shi, Guang‐Peng Qu, Xu Yin, Yong‐Kang Zhang, Ying‐Jie Sun, Zhen Luo, Wei Li, Chun‐Ping Zhang, Jie‐Jun Xi   +9 more
wiley   +1 more source

Effect of S-adenosylmethionine on human rotavirus RNA synthesis [PDF]

, 1984
The characteristics of human rotavirus-associated RNA polymerase activity have been examined in relation to the effects of ribonucleoside triphosphate analogs and S-adenosylmethionine.
GARCIA,, Spencer, Nicolás
core  

Mini Review: Scientific Analysis of Radical S-Adenosylmethionine (SAM) Enzymes [PDF]

The radical S-Adenosylmethionine (SAM) superfamily of enzymes catalyzes a diverse range of reactions ranging from hydrogen abstraction to complicated multistep reactions such as insertions and rearrangements. The reactions they catalyze are utilized in a
Gallage H. D. N., Ariyaratne
core   +1 more source

Cysteine Restriction Induces Ferroptosis Depending on the S-adenosylmethionine and Polyamine Biosynthetic Pathways in Hepatic Cancer Cells

Gastro Hep Advances
Background and Aims: Liver diseases such as hepatocellular carcinoma are known to be affected by nutrition and metabolic activities, but the mechanisms behind them remain unclear.
Keisuke Tada, Kazuki Mitsuyama, Hironari Nishizawa, Hiroki Shima, Akihiko Muto, Motoshi Wada, Daisuke Saigusa, Kazuhiko Igarashi   +7 more
doaj   +1 more source

S-Adenosylmethionine Synthetase 3 Is Important for Pollen Tube Growth1[OPEN]

Plant Physiology, 2016
Arabidopsis mat3 pollen overaccumulates methionine, germinates poorly, and has short tubes. S-Adenosylmethionine is widely used in a variety of biological reactions and participates in the methionine (Met) metabolic pathway.
Yuan Chen, Ting Zou, S. McCormick
semanticscholar   +1 more source

The Analysis of S-Adenosylmethionine and S-Adenosylhomocysteine in Normal and Neoplastic Cells [PDF]

, 1980
Altered patterns of methylation have been shown in both ribosomal and transfer RNA isolated from cancer cells. In contrast to the elevated activity of the methyltransferases responsible for this modification, hypomethylation appears as a general ...
Godburn, Kathryn Elizabeth
core   +1 more source

Crystallographic capture of a radical S-adenosylmethionine enzyme in the act of modifying tRNA

Science, 2016
An RNA methylase caught in the act RNA methylation is important in RNA function and in antibiotic resistance. The RNA methylase RlmN is a dual-specificity enzyme that can act on ribosomal and transfer RNA (tRNA).
Erica L. Schwalm, T. Grove, S. Booker, A. Boal   +3 more
semanticscholar   +1 more source

Multi‐omics–driven precision medicine

iMeta, EarlyView.
Multi‐omics‐driven precision medicine (MODPM) provides a multiscale, continuously learnable framework that integrates genomics, epigenomics, transcriptomics, proteomics, metabolomics, microbiome profiles, and clinical data. Powered by artificial intelligence and foundation models, MODPM enables cross‐modal representation learning, contextual modeling ...
Huibo Li, Zhe Zhao, Yifan Zhang, Yao Ma, Gaofei Hu, Min Zeng, Zhanqun Yang, Zixuan Zhao, Xin Zhou, Wei Hu, Yuxuan Sun, Meng Su, Jun Li, Matthew Whiteman, Wei Fu, Chao Zhong, Lemin Zheng, Long Chen, Hairong Lv, Rongsheng Zhao, Yi Zhun Zhu   +20 more
wiley   +1 more source

Vitamin B12-impaired metabolism produces apoptosis and Parkinson phenotype in rats expressing the transcobalamin-oleosin chimera in substantia nigra.

PLoS ONE, 2009
BackgroundVitamin B12 is indispensable for proper brain functioning and cytosolic synthesis of S-adenosylmethionine. Whether its deficiency produces effects on viability and apoptosis of neurons remains unknown.
Carlos Enrique Orozco-Barrios, Shyue-Fang Battaglia-Hsu, Martha Ligia Arango-Rodriguez, Jose Ayala-Davila, Celine Chery, Jean-Marc Alberto, Henry Schroeder, Jean-Luc Daval, Daniel Martinez-Fong, Jean-Louis Gueant   +9 more
doaj   +1 more source

Role of S-adenosylmethionine cycle in carcinogenesis.

General Physiology and Biophysics, 2017
Alterations in enzymatic activities underlying the cellular capacity to maintain functional S-adenosylmethionine (SAM) cycle are associated with modified levels of its constituents. Since SAM is the most prominent donor of methyl group for sustaining the
R. Murín, Eva Vidomanová, B. Kowtharapu, J. Hatok, D. Dobrota   +4 more
semanticscholar   +1 more source