Results 141 to 150 of about 764,898 (194)

OXCT1‐driven succinylation of PSMG3 stabilizes the proteasome to facilitate picornavirus replication

iMetaOmics, EarlyView.
Upon entering the pig, foot‐and‐mouth disease virus (FMDV) regulates host glycolysis and the citrate cycle by modulating the expression of metabolic enzymes, resulting in changes in post‐translational modifications (PTMs) including succinylation, lactylation, crotonylation, acetylation, and phosphorylation.
Huisheng Liu, Qiao Xue, Pengfei Liu, Zhihua Dong, Weijun Cao, Fan Yang, Yingming Zhu, Lei Deng, Zixiang Zhu, Haixue Zheng   +9 more
wiley   +1 more source

Synthesis, Cytotoxicity, and Apoptosis‐Associated Cell Death Activity of an Isatin‐Containing Pyrimidine‐Derived Cu(II) Complex

Journal of Applied Toxicology, EarlyView.
ABSTRACT A Cu(II) complex derived from a pyrimidine with the isatin group was synthesized and tested for its cytotoxic effects on A549 lung cancer and MCF‐7 breast cancer cell lines, as well as its effects on apoptosis‐associated cell death and cell cycle regulation in A549 cells. To evaluate cytotoxicity, MTT assays were performed at 24, 48, and 72 h,
Müjgan Kesik Oktay, Cansu Topkaya, Elif Kağa, Yasin Eren, Ramazan Güp   +4 more
wiley   +1 more source

The Crude Venom of the Whitetail Lancehead, Bothrops leucurus, and Two of Its Enzymatic Components Are Selectively Cytotoxic for Glioma Cells In Vitro

Journal of Applied Toxicology, EarlyView.
ABSTRACT Malignant glioma is the most common primary brain tumor, and glioblastoma multiforme (GBM) remains its most aggressive and incurable form. Snake venoms contain bioactive compounds with promising antitumoral properties against several cancer types.
M. O. H. V. Rosário, T. M. Fucase, P. J. Spencer, J. M. Sciani, J. Clarêncio, G. Rádis‐Baptista, L. L. Casais‐e‐Silva, R. S. El‐Bachá   +7 more
wiley   +1 more source

Vitamin B12 deficiency in an infant secondary to nutritional deficiency and an inadequate maternal diet

JPGN Reports, EarlyView.
ABSTRACT Vitamin B12 (cobalamin, Cbl) is an essential micronutrient for DNA synthesis and neurological development. Its deficiency in infants, although infrequent in developed countries, can cause megaloblastic anemia, psychomotor delay, and neurological damage that may become irreversible if not treated early.
Sandra Sala‐Lluch, Nerea Mesas‐Vila, Susana Ferrando‐Monleón, Ana Barrés‐Fernández, Cristina Villar‐Vera, José Vicente Arcos‐Machancoses   +5 more
wiley   +1 more source

Development of mango‐flavored soy‐based yogurt: Assessment of physicochemical properties and quality attributes

JSFA reports, EarlyView.
Abstract Background Yogurt is a widely consumed fermented dairy product valued for its nutritional quality, functional benefits, and formulation flexibility. Rising consumer interest in healthier and diversified foods has increased attention toward composite plant–dairy yogurts enriched with fruits and legumes.
Richard Osae, Maurice Tibiru Apaliya, Marvel Hinson, Rahima Naa Lamiokor Ishmael, Ellen Nkrumah Quayson, Salomey Danso, Francisca Ekua Enchill, Raphael N. Alolga, Eric Antiri Aforo, Emmanuel kwaw   +9 more
wiley   +1 more source

Macronutrient and micronutrient profiles of meat types: insights into human health and diet

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Despite considerable advances in global health and nutrition, emerging challenges such as population growth, climate change, and limited natural resources continue to threaten food security. Meat remains an essential component of the human diet, supplying high‐quality proteins, essential amino acids, lipids, vitamins, and minerals necessary ...
Özgül Anitaş, Serap Göncü, Fatma Hepsağ, Nazan Koluman, Yesim Ozogul   +4 more
wiley   +1 more source

myo‐Inositol's role in laying hens’ active gastrointestinal microbiota: a strain comparison

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND myo‐Inositol (MI) is a cyclitol involved in cellular metabolism and phytate degradation, yet its influence on the gastrointestinal tract (GIT) microbiota of laying hens remains poorly understood. This study investigated the effects of graded dietary MI supplementation on the active GIT microbial communities of two commercial laying ...
Naomi Sarpong, Christoph Roth, Markus Rodehutscord, Jana Seifert, Amélia Camarinha‐Silva   +4 more
wiley   +1 more source

Evolution of free amino acids and volatile compounds in dry‐cured fermented 'salchichón' sausages superficially inoculated with different molds

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Surface molds contribute to flavor development in dry‐cured fermented sausages through their effects on proteolysis, amino acid catabolism, and volatile compound formation. This study evaluated the influence of Aspergillus oryzae, Penicillium camemberti, Penicillium roqueforti and Penicillium nalgiovense on the evolution of free ...
José María Martín‐Miguélez, Alberto González‐Mohino, Jorge Ruiz‐Carrascal, Lary Souza Olegario, Josué Delgado   +4 more
wiley   +1 more source

Characterizing vineyard‐specific differences in Pinot Noir grape composition in relation to soil properties and rhizosphere microbial communities

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Grape berry chemical composition is closely linked to wine quality and provides important information for vineyard management. However, the relationships between berry composition, vineyard soil conditions and rhizosphere microbial communities remain insufficiently understood.
Ziyu Li, Romy Moukarzel, Leandro Dias Araujo, Olaf Schelezki, Blair Walter, Bin Tian   +5 more
wiley   +1 more source

Modulation of oxidative metabolism and quality preservation of strawberries by a CMC–alginate bilayer edible coating during cold storage

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Strawberries are highly perishable fruits characterized by rapid postharvest deterioration, leading to significant quality losses and reduced marketability. In this study, a bilayer edible coating based on carboxymethylcellulose and sodium alginate was evaluated for its ability to preserve strawberry quality during cold storage ...
Ilenia Pellicano, Riccardo Riggi, Elvira Ferrara, Danilo Cice, Margherita Modesti, Milena Petriccione, Andrea Bellincontro   +6 more
wiley   +1 more source