Rate of endogenous methionine oxidation in rats at different levels of methionine intake [PDF]
British Journal of Nutrition, 1983 1. The fractional rates of loss of 14C and body-weight were measured in growing female rats after a single dose of [1-14C]methionine. After the dose, the rats were maintained for 30 d on diets containing graded amounts of methionine and killed at 30 d.2. By 20 d after the dose the level of labelling of body proteins was fairly uniform. From 20 to 30 d,
R J, Neale, J C, Waterlow
openaire +2 more sources
Oxidation Resistance of the Sulfur Amino Acids: Methionine and Cysteine [PDF]
, 2017 Sulfur amino acids are a kind of amino acids which contain sulfhydryl, and they play a crucial role in protein structure, metabolism, immunity, and oxidation.
Ruilin Huang, Peng Bin, Xihong Zhou
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Metabolites of ethanol as markers of alcohol abuse : glutathione consumption and methionine kinetics in humans [PDF]
, 2004 In the course of the present doctoral studies two projects related to research in alcoholism and relevant for the postgraduate formation of a pharmacist were pursued: one project dealt with the development of analytical tools applicable to the ...
Schmid, Andreas Ulrich
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Monitoring of methionine oxidation with fluorescent proteins [PDF]
, 2021 Methionine (Met) oxidation to methionine sulfoxide (MetO) is a post-translational protein modification that can appear unspecifically during exposure of Met to oxidants in normal growth and oxidative stress, such as occurring in aged organisms and in ...
Kuldyushev, Nikita
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Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Selective Oxidation of Methionine and Tryptophan Residues in a Therapeutic IgG1 Molecule
, 2015 Oxidation of methionine and tryptophan are common degradation pathways for monoclonal antibodies and present major analytical challenges in biotechnology.
Koulov, Atanas V. +17 more
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DNA ligase LigE increases bacterial transformation with damaged extracellular DNA
FEBS Letters, EarlyView.The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan +4 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Kinetics and mechanism of oxidation of methionine by chloramine-T in alkaline medium in presence of OsO4 catalyst [PDF]
, 1999 Kinetics and mechanism of oxidation of D-L methionine (Met) by sodium N-chlorotoluene-p-sulphanamide (CBT) in alkaline medium in presence of OsO4 catalyst have been investigated at 30 degrees C, and the results are compared to the reaction without Os ...
Demappa, T., Ananda, S.
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