Human methionine synthase A2756G polymorphism increases susceptibility to prostate cancer. [PDF]
Aging (Albany NY), 2018 Shao HB +8 more
europepmc +1 more source
Methionine synthase A2756G polymorphism influences pediatric acute lymphoblastic leukemia risk: a meta-analysis. [PDF]
Biosci Rep, 2019 Ma LM, Yang HP, Yang XW, Ruan LH.
europepmc +1 more source
A single-nucleotide polymorphism (rs1805087) in the methionine synthase (METH) gene increases the risk of prostate cancer. [PDF]
Aging (Albany NY), 2018 Zhang X, Tang J, Shen N, Ren K.
europepmc +1 more source
Characterization and Crystal Structure Elucidation of the l-Homoserine O-Succinyltransferase MetXS From Cupriavidus necator H16. [PDF]
ChembiochemMeier HPF +5 more
europepmc +1 more source
Cobalamin Uptake and Reactivation Occurs Through Specific Protein Interactions in the Methionine Synthase–Methionine Synthase Reductase Complex [PDF]
FEBS Journal, 2009 Human methionine synthase reductase (MSR), a diflavin enzyme, restores the activity of human methionine synthase through reductive methylation of methionine synthase (MS)‐bound cob(II)alamin. Recently, it was also reported that MSR enhances uptake of cobalamin by apo‐MS, a role associated with the MSR‐catalysed reduction of ...
Kirsten R Wolthers, Nigel Scrutton
exaly +4 more sources
Methionine Synthase and Methionine Synthase Reductase Interact With MMACHC and With MMADHC
Biochimica Et Biophysica Acta - Molecular Basis of Disease, 2017 An increasing number of studies indicate that each step of the intracellular processing of vitamin B12 or cobalamin (Cbl) involves protein-protein interactions. We have previously described a novel interaction between methionine synthase (MS) and MMACHC and its effect on the regulation of MMACHC activity.
David Coelho +2 more
exaly +5 more sources
Polymorphism of the Methionine Synthase Gene
Arteriosclerosis, Thrombosis, and Vascular Biology, 1999 —Methionine synthase and 5,10-methylenetetrahydrofolate reductase (MTHFR) sequentially catalyze the remethylation of homocysteine to methionine. A point mutation in the encoding region of the methionine synthase gene, which results in substitution of an ...
Takayuki Shindo +2 more
exaly +2 more sources
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Polymorphisms of methylenetetrahydrofolate reductase (MTHFR) gene are strongly associated with hypertension incidence, although such association is inconsistent among ethnicities studied. However, effects of polymorphisms of other genes related to folate metabolism besides MTHFR on hypertension susceptibility are not well known yet.The aim of this ...
Young Ree Kim +2 more
openaire +4 more sources
The aim of the study was to determine the MTR (methionine synthase) and MTRR (mehionine synthase reductase) polymorphisms in pregnant women with preeclampsia (PE).The group of 98 women with PE and the group of 120 healthy pregnant women were analyzed.
Anna Bogacz +2 more
exaly +3 more sources