Late‐onset refractory hemolytic anemia in siblings treated for methionine synthase reductase deficiency: A rare complication possibly prevented by hydroxocobalamin dose escalation? [PDF]
JIMD ReportsMethionine synthase reductase deficiency (cblE) is a rare autosomal recessive inborn error of cobalamin metabolism caused by pathogenic variants in the methionine synthase reductase gene (MTRR).
Alexandre Nguyen +7 more
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Associations of the A66G Methionine Synthase Reductase Polymorphism in Colorectal Cancer: A Systematic Review and Meta-Analysis [PDF]
Biomarkers in Cancer, 2015 Hamdi Jarjanazi +2 more
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Chlorquinaldol Alleviates Lung Fibrosis in Mice by Inhibiting Fibroblast Activation through Targeting Methionine Synthase Reductase [PDF]
ACS Central ScienceXiangyu Yang +15 more
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Role of folate metabolizing genes and homocysteine in mothers of Down syndrome children
Tzu Chi Medical Journal, 2022 Objectives: Folates are essential nutrients required for the synthesis of DNA/RNA in cell division and segregation. Folates are reduced and methylated in the liver with the help of enzymes such as methylenetetrahydrofolate reductase (MTHFR), MTR MTRR ...
Amandeep Kaur, Anupam Kaur
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Redox Biology, 2020 Using Caenorhabditis elegans as a model animal, we evaluated the effects of chronical supplementation with high-dose folic acid on physiological events such as life cycle and egg-laying capacity and folate metabolism.
Kyohei Koseki +4 more
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Methionine synthase reductase A66G polymorphism and ischemic stroke in younger patients
Неврология, нейропсихиатрия, психосоматика, 2021 In the past decade, stroke incidence in younger adults increased. Methionine synthase reductase (MTRR) A66G polymorphism is one of the risk factors for ischemic stroke (IS).
O. V. Tsyganenko +2 more
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SAGE Open Medicine, 2020 Background: Hyperhomocysteinemia, a thrombotic risk factor, may have several causes. Among the genetic causes of hyperhomocysteinemia, there are polymorphisms in the enzymes methylenetetrahydrofolate reductase (C677T) and cystathionine β-synthase (C699T,
Anahi Guadalupe Figueroa-Torres +10 more
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Association between folate metabolism polymorphisms and breast cancer: a case-control study
Genetics and Molecular Biology, 2021 We investigated the association between methylenetetrahydrofolate reductase (MTHFR C677T and A1298C), methionine synthetase (MTR A2756G), and methionine synthase reductase (MTRR A66G) polymorphisms involved in folate pathway and breast cancer risk, and ...
Ana Paula D’Alarme Gimenez-Martins +9 more
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Distribution of MTHFR and MTRR polymorphisms in Han and Buyi women at Libo county of Guizhou province [PDF]
Jichu yixue yu linchuang, 2021 Objective To conduct molecular epidemiological investigations on Han and Buyi women at Libo county of Guizhou province aiming for the identification of genetic polymorphisms coding the key enzymes for folate metabolism MTHFR and MTRR.
QIN Yi-wang, MO Mei-xiang, ZHANG Long-jiong, LUO Yin-ya, WEI Liang-yin, HU Ji-fang, LU Yan-qiang
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DISTRIBUTION OF MTHFR C677T, A1298C POLYMORDHISMS, AND MTRR A66G POLYMORPHISMS IN HAN WOMEN IN JIA COUNTY, CHINA [PDF]
精准医学杂志, 2023 Objective To analyze the distribution characteristics of the gene polymorphisms of key enzymes related to folate metabolism [5,10-methylenetetrahydrofolate reductase (MTHFR) and methionine synthase reductase (MTRR)] in women of reproductive age of the ...
LI Huicong, WU Hongguo, LU Yanqiang, WANG Yanchao, WANG Qiuju, HU Jifang, YANG Q
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