Results 41 to 50 of about 348,762 (206)

Polymorphism of MTHFR and MTRR genes in childbearing-aged Han women in Zhongyuan district of Zhengzhou city [PDF]

Jichu yixue yu linchuang, 2020
Objective The high-risk population with poor folic acid utilization of childbearing age women was screened by gene detection technology to guide women of childbearing age to supplement folic acid reasonably.
GUO Ting-ting, LIU Fang, GUI Jing, YANG Xiao-feng
doaj  

Association of maternal genetic polymorphisms with fetal growth restriction syndrome in Russian pregnant women from Rostov region

Egyptian Journal of Medical Human Genetics, 2023
Background Fetal growth restriction (FGR) is one of the main syndromes causing fetal morbidity and mortality. It was known to be associated with different factors including maternal, fetal, and environmental. However, the effect of genetic factors in FGR
Dema Alset, Elena Viktorovna Butenko, Inna Olegovna Pokudina, Tatiana Pavlovna Shkurat, Ekaterina Andreevna Zabanova, Natalia Borisovna Kuznetsova   +5 more
doaj   +1 more source

Isolated and Combined Remethylation Disorders

Journal of Inborn Errors of Metabolism and Screening, 2017
Genetic defects affecting the remethylation pathway cause hyperhomocysteinemia. Isolated remethylation defects are caused by mutations of the 5, 10-methylenetetrahydrofolate reductase (MTHFR) , methionine synthase reductase (MTRR) , methionine synthase ...
Eva Richard PhD, Sandra Brasil PhD, Fátima Leal, Rosa Navarrete, Ana Vega PhD, María Jesús Ecay, Lourdes R. Desviat PhD, Celia Pérez-Cerda PhD, Magdalena Ugarte PhD, Begoña Merinero PhD, Belén Pérez PhD   +10 more
doaj   +1 more source

Methionine synthase A2756G polymorphism may predict ulcerative colitis and methylenetetrahydrofolate reductase C677T pancolitis, in Central China

BMC Medical Genetics, 2008
Background The association of genetic polymorphisms related to metabolism of homocysteine with inflammatory bowel disease has been evidenced in Crohn disease and remains an open question in ulcerative colitis.
Bronowicki Jean-Pierre, Guéant-Rodriguez Rosa-Maria, Xia Bing, Peyrin-Biroulet Laurent, Chen Min, Bigard Marc-André, Guéant Jean-Louis   +6 more
doaj   +1 more source

3’UTR polymorphism of Thymidylate Synthase gene increased the risk of persistence of pre-neoplastic cervical lesions

BMC Cancer, 2020
Background Cervical cancer is caused by high-risk Human Papillomavirus (hr-HPV) infection associated with cofactors that has been analyzed as predictors of the remission or persistence of cytological abnormalities remission or persistence.
Nayara Nascimento Toledo Silva, Ana Carolina Silva Santos, Verlândia Mendes Nogueira, Cláudia Martins Carneiro, Angélica Alves Lima   +4 more
doaj   +1 more source

Underground Signals: The Ecological Power of Root Volatiles

Advanced Science, EarlyView.
Root volatiles mediate rhizosphere chemical communication, shaping interactions among plants, microbes, herbivores, and natural enemies. Their production, transport, and perception underpin ecological adaptation, multitrophic interactions, and plant resilience, offering opportunities for sustainable crop protection, resilient agroecosystems, and ...
Xueyao Cao, Nanli Song, François Verheggen, Meritxell Pérez‐Hedo, Andrea Clavijo McCormick, Antonino Cusumano, Arthur de Fouchier, Bing Wang, Chen‐Zhu Wang, Emmanuelle Jacquin‐Joly, Gary W. Felton, Geoff M. Gurr, Hao Guo, Jiancai Li, Jin Zhang, Li Chen, Manqun Wang, Michele Ricupero, Peng Han, Peng He, Qi Yan, Qingbo Tang, Qingsong Liu, Shiheng An, Xiangbo Kong, Xiaoling Sun, Xueming Ren, Yuanyuan Song, Yang Liu, Yanhui Guo, Yunhe Li, Xiao Sun   +31 more
wiley   +1 more source

Effect of methionine synthase A2756G and methionine synthase reductase A66G gene polymorphisms in male infertility

Urology Research and Practice, 2019
Objective: In this study, we investigated whether methionine synthase (MTR) A2756G and methionine synthase reductase (MTRR) A66G gene polymorphisms were related with infertility.
Ali Şahin Küçükaslan, Raşit Altıntaş, Vildan Bozok Çetintaş, Aslı Tetik, Murat Ulukuş, Bülent Semerci, Zuhal Eroğlu   +6 more
doaj   +2 more sources

Sex‐ and Time‐Resolved Physiological and Gut Ecosystem Responses to a Food‐Grade Microbiome‐Targeted Intervention in Collegiate Endurance Athletes

Advanced Science, EarlyView.
In collegiate endurance athletes, a 6‐week randomized CPYE intervention yielded time‐ and sex‐dependent shifts in field‐based cardiorespiratory, metabolic, and redox indices, accompanied by changes in gut multi‐omics profiles. An exploratory extension during intensified training generates hypotheses warranting future validation.
Meng Zhang, Le Ge, Kaiyang Liu, Yanrong Liu, Guolin Zhao, Lai‐Yu Kwok, Zheng Sun, Zhihong Sun, Wenyi Zhang   +8 more
wiley   +1 more source

A Novel Reactive Oxygen Species‐Responsive Bone‐Targeted Nanoplatform Based on Cloperastine Attenuates Ovariectomy‐Induced Bone Loss by Inhibiting Osteoclast Oxidative Phosphorylation

Advanced Science, EarlyView.
Cloperastine suppresses osteoclastogenesis by inhibiting PGC1β‐mediated oxidative phosphorylation. Its incorporation into a ROS‐responsive, Asp8‐modified nanoplatform enhances skeletal accumulation. The resulting Clo/Asp8‐PMK‐MCs combine cloperastine‐mediated antiresorptive activity with carrier‐mediated osteogenic activity to attenuate OVX‐induced ...
Haibo Liang, Yong Xiao, Jiangtao Luo, Xiao Yang, Yayun Yang, Qihang Wu, Chenxin Yu, Zhihao Zhou, Xiaoqing Si, Jiansen Miao, Yiting Tu, Qichen Lu, Boreng Qian, Xiangyang Wang, Jiake Xu, Changcan Shi, Haiming Jin   +16 more
wiley   +1 more source

Genetic variation in folate metabolism is associated with the risk of conotruncal heart defects in a Chinese population

BMC Pediatrics, 2018
Background Conotruncal heart defects (CTDs) are a subgroup of congenital heart defects that are considered to be the most common type of birth defect worldwide. Genetic disturbances in folate metabolism may increase the risk of CTDs. Methods We evaluated
Xike Wang, Haitao Wei, Ying Tian, Yue Wu, Lei Luo   +4 more
doaj   +1 more source