Results 61 to 70 of about 320,148 (311)

Bayesian curve estimation by model averaging [PDF]

open access: yes, 2003
A bayesian approach is used to estimate a nonparametric regression model. The main features of the procedure are, first, the functional form of the curve is approximated by a mixture of local polynomials by Bayesian Model Averaging (BMA); second, the ...
Peña, Daniel, Redondas, María Dolores
core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Method of Averaging in Clifford Algebras [PDF]

open access: yesAdvances in Applied Clifford Algebras, 2015
15 ...
openaire   +2 more sources

Peak response of non-linear oscillators under stationary white noise

open access: yes, 2007
YesThe use of the Advanced Censored Closure (ACC) technique, recently proposed by the authors for predicting the peak response of linear structures vibrating under random processes, is extended to the case of non-linear oscillators driven by stationary ...
Palmeri, Alessandro, Muscolino, G.
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Weighted Inter-frame Averaging-Based Channel Estimation for CO-OFDM System

open access: yesIEEE Photonics Journal, 2013
We propose an efficient channel estimation method for coherent optical orthogonal frequency-division multiplexing (CO-OFDM) based on weighted inter-frame averaging (WIFA), in which the channel estimation results of the adjacent frames are averaged to ...
Hui Zhao   +7 more
doaj   +1 more source

Time Synchronous Averaging Based on Cross-power Spectrum

open access: yesChinese Journal of Mechanical Engineering, 2023
Periodic components are of great significance for fault diagnosis and health monitoring of rotating machinery. Time synchronous averaging is an effective and convenient technique for extracting those components.
Ling Wang   +3 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

How to average logarithmic retrievals? [PDF]

open access: yesAtmospheric Measurement Techniques, 2012
Calculation of mean trace gas contributions from profiles obtained by retrievals of the logarithm of the abundance rather than retrievals of the abundance itself are prone to biases.
B. Funke, T. von Clarmann
doaj   +1 more source

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