Results 251 to 260 of about 582,283 (312)

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

"Go neurological physical therapy research, go"! Volume and methodological quality of neurological physical therapy: A 63-year PEDro database analyses. [PDF]

Braz J Phys Ther
Vasconcelos JM, Viana YG, Pinheiro MB, Aguiar LT, Polese JC.   +4 more
europepmc   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

Critical appraisal of methodological quality and completeness of reporting in Chinese social science systematic reviews with meta-analysis: A systematic review. [PDF]

Campbell Syst Rev
Guo L, Miller S, Zhou W, Wei Z, Ren J, Huang X, Xing X, White H, Yang K.   +8 more
europepmc   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Methodological Quality and Content of Guidelines on Early Childhood Allergy Prevention: A Systematic Assessment and Content Analysis. [PDF]

Matern Child Nutr
Sieferle K, Bitzer EM.
europepmc   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source

Reported methodological quality of medical systematic reviews: Development of an assessment tool (ReMarQ) and meta-research study. [PDF]

Res Synth Methods
Marques-Cruz M, Vieira RJ, Martinho-Dias D, Barbosa JP, Cardoso-Fernandes A, Franco-Pêgo F, Perestrelo P, Gil-Mata S, Taveira-Gomes T, Pêgo JM, Fonseca JA, Azevedo LF, Sousa-Pinto B.   +12 more
europepmc   +1 more source

Oxford Shoulder Instability Score: cross-cultural adaptation into Spanish and analysis of its methodological quality. [PDF]

BMC Musculoskelet Disord
Aldon-Villegas R, Chamorro-Moriana G, Espuny-Ruiz F, Benitez-Lugo ML.   +3 more
europepmc   +1 more source