Results 81 to 90 of about 13,391,377 (337)
Research methodology in montanistic tourism [PDF]
, 2017 Research methodology in montanistic tourism involves the archival research and study of special literature, surface and underground field survey, the analysis of findings of rock fragments, mineral composition, traces of metallurgical processes ...
Schejbal, Ctirad
core
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Nucleic Acids Res., 2016 The degree of evolutionary conservation of an amino acid in a protein or a nucleic acid in DNA/RNA reflects a balance between its natural tendency to mutate and the overall need to retain the structural integrity and function of the macromolecule.
Haim Ashkenazy +6 more
semanticscholar +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Journal of Education, Health and Sport, 2018 Introduction. Measles is a highly contagious disease capable of inducing epidemics, which strike every 2 to 3 years. Before implementing the vaccine in 1963 measles was devastating communities leading to 135 million of victims and 6 million died because ...
Dorota Sokół +5 more
doaj +3 more sources
Trials, 2023 Background In a non-inferiority trial, the choice of margin depends on the expected control event risk. If the true risk differs from expected, power and interpretability of results can be affected. A non-inferiority frontier pre-specifies an appropriate
Matteo Quartagno +4 more
doaj +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
A Methodology for Afterburner Evaluation [PDF]
, 1996 A preliminary investigation of the performance of an afterburner module proposed by the Gas Turbine Research Establishment, Bangalore for the Kaveri engine has been carried out.
Haran, AP +6 more
core
Quantifying Bar Strength: Morphology Meets Methodology
, 2004 A set of objective bar-classification methods have been applied to the Ohio State Bright Spiral Galaxy Survey (Eskridge et al. 2002). Bivariate comparisons between methods show that all methods agree in a statistical sense.
BG Elmegreen +9 more
core +2 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source