Results 31 to 40 of about 3,716,507 (339)
FEBS Letters, Volume 599, Issue 6, Page 901-911, March 2025.The human Na+/H+ antiporter NHA2 transports Na+ or Li+ in exchange for protons across cell membranes, and its dysfunction results in various pathologies, e.g., fertility disorders, hypertension, or diabetes. This work provides the molecular characterization of interactions of NHA2 with its specific inhibitor phloretin, which can be helpful for the ...
Olga Zimmermannova +3 more
wiley +1 more source
iScience, 2021 Summary: The current severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has created a significant threat to global health. While respiratory aerosols or droplets are considered as the main route of human-to-human transmission ...
Daniel Todt +17 more
doaj
Professare, 2023 O uso de metodologias ativas (MA) e o ensino com enfoque Ciência, Tecnologia e Sociedade (CTS) podem ser meios para estimular o processo de ensino-aprendizagem ativo e crítico. O presente estudo objetivou avaliar a contribuição das estratégias ativas, como o Role play e a Rotação por Estações de Aprendizagem, para o ensino sob a perspectiva CTS na ...
Aline Lubyi LUBYI +3 more
openaire +1 more source
Applying Graph Theory to Examine the Dynamics of Student Discussions in Small-Group Learning. [PDF]
, 2019 Group work in science, technology, engineering, and mathematics courses is an effective means of improving student outcomes, and many different factors can influence the dynamics of student discussions and, ultimately, the success of collaboration.
Chai, Albert +3 more
core +1 more source
FEBS Letters, Volume 599, Issue 6, Page 876-891, March 2025.We explore 5HT2A receptor activation, a key target for psychedelic drugs, using molecular dynamics simulations. Without Gqα, the active receptor collapses to an inactive conformation, underscoring the G‐protein's role. Discovery of an intermediate “partially‐open” state and the higher affinity of ligands to the orthosteric binding site provides ...
Niklas Viohl +2 more
wiley +1 more source
Robust induction of functional astrocytes using NGN2 expression in human pluripotent stem cells
iScience, 2023 Summary: Emerging evidence of species divergent features of astrocytes coupled with the relative inaccessibility of human brain tissue underscore the utility of human pluripotent stem cell (hPSC) technologies for the generation and study of human ...
Martin H. Berryer +15 more
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Modelling Cell Cycle using Different Levels of Representation [PDF]
EPTCS 11, 2009, pp. 51-69, 2009 Understanding the behaviour of biological systems requires a complex setting of in vitro and in vivo experiments, which attracts high costs in terms of time and resources. The use of mathematical models allows researchers to perform computerised simulations of biological systems, which are called in silico experiments, to attain important insights and ...
arxiv +1 more source
Why Biology is Beyond Physical Sciences? [PDF]
, 2016 In the framework of materialism, the major attention is to find general organizational laws stimulated by physical sciences, ignoring the uniqueness of Life.
Muni, Bhakti Vijnana +1 more
core +1 more source
FEBS Letters, Volume 599, Issue 8, Page 1113-1121, April 2025.The glacier ice worm Mesenchytraeus solifugus survives year‐round at 0 °C. Its ATP6 subunit, which forms a regulatory component of the proton pore in mitochondrial ATP synthase, has a carboxy‐terminal extension not found in any other organism examined to date. Here, we show that fusion of this extension to the homologous AtpB protein in E. coli results
Truman Dunkley +2 more
wiley +1 more source
Antibody-based sex determination of human skeletal remains
iScience, 2023 Summary: Assignment of biological sex to skeletal remains is critical in the accurate reconstruction of the past. Analysis of sex-chromosome encoded AMELX and AMELY peptides from the enamel protein amelogenin underpins a minimally destructive mass ...
Barry Shaw +10 more
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