Results 41 to 50 of about 491,032 (299)

Uniform transgene activation in Tet-On systems depends on sustained rtTA expression

open access: yesiScience, 2023
Summary: Application of the tetracycline-inducible gene expression system (Tet-On) in human induced pluripotent stem cells (hiPSCs) has become a fundamental transgenic tool owing to its regulatable gene expression.
Jun Otomo   +2 more
doaj   +1 more source

Wake respirometry allows breath-by-breath assessment of ventilation and CO2 production in unrestrained animals

open access: yesiScience, 2022
Summary: Quantifying stress and energetic responses in animals are major challenges, as existing methods lack temporal resolution and elevate animal stress.
Kayleigh A.R. Rose   +5 more
doaj   +1 more source

Detection and annotation of transposable element insertions and deletions on the human genome using nanopore sequencing

open access: yesiScience, 2023
Summary: Repetitive sequences represent about 45% of the human genome. Some are transposable elements (TEs) with the ability to change their position in the genome, creating genetic variability both as insertions or deletions, with potential pathogenic ...
Javier Cuenca-Guardiola   +7 more
doaj   +1 more source

Biomimicry design thinking education: a base-line exercise in preconceptions of biological analogies

open access: yes, 2020
Preliminary empirical research conducted by the leading author has shown that design students using biological analogies, or models across different contexts, often misinterpreted these, intentionally or unintentionally, during design.
Laura Stevens   +3 more
semanticscholar   +1 more source

Optimization of MHD Flow of Radiative Micropolar Nanofluid in a Channel by RSM: Sensitivity Analysis

open access: yesMathematics, 2023
These days, heat transfer plays a significant role in the fields of engineering and energy, particularly in the biological sciences. Ordinary fluid is inadequate to transfer heat in an efficient manner, therefore, several models were considered for the ...
Reham A. Alahmadi   +5 more
semanticscholar   +1 more source

The unpredictably eruptive dynamics of spruce budworm populations in eastern Canada

open access: yesPopulation Ecology, EarlyView.
We examine historical population data for spruce budworm from several locations through the period 1930–1997, and use density‐dependent recruitment curves to test whether the pattern of population growth over time is more consistent with Royama's (1984; Ecological Monographs 54:429–462) linear R(t) model of harmonic oscillation at Green River New ...
Barry J. Cooke, Jacques Régnière
wiley   +1 more source

Seeing Natural Images through the Eye of a Fly with Remote Focusing Two-Photon Microscopy

open access: yesiScience, 2020
Summary: Visual systems of many animals, including the fruit fly Drosophila, represent the surrounding space as 2D maps, formed by populations of neurons. Advanced genetic tools make the fly visual system especially well accessible.
Anna Schuetzenberger, Alexander Borst
doaj   +1 more source

Epitranscriptome analysis of NAD-capped RNA by spike-in-based normalization and prediction of chronological age

open access: yesiScience, 2023
Summary: Nicotinamide adenine dinucleotide (NAD) can be used as an initiating nucleotide in RNA transcription to produce NAD-capped RNA (NAD-RNA).
Dean Li   +11 more
doaj   +1 more source

The "Gut Game": an active methodology to teach digestive physiology.

open access: yesAdvances in Physiology Education, 2020
Rafael Paschoal de Campos, Victória Pereira Viero, Natascha Monteiro Medeiros, Fernanda Klein Marcondes, X Luís Henrique Montrezor, Marilene Porawski, and Lucila Ludmila Paula Gutierrez Biomedicine Undergraduate Program, Federal University of Health ...
R. P. de Campos   +6 more
semanticscholar   +1 more source

Single‐cell insights into the role of T cells in B‐cell malignancies

open access: yesFEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

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