Results 41 to 50 of about 3,716,507 (339)

Diffusive optical tomography in the Bayesian framework [PDF]

open access: yes, 2019
Many naturally-occuring models in the sciences are well-approximated by simplified models, using multiscale techniques. In such settings it is natural to ask about the relationship between inverse problems defined by the original problem and by the ...
Li, Qin, Newton, Kit, Stuart, Andrew
core   +1 more source

The outset of U-I R&D relationships: the specific case of biological sciences [PDF]

open access: yes, 2015
Purpose – The purpose of this paper is to draw insights from the actors-resources-activities (ARA) model and social capital literature to identify relevant activities shared by university-industry (U-I) actors prior to R&D cooperation.
Lucas, Cândida   +2 more
core   +1 more source

The apo LETM1 F‐EF‐hand adopts a closed conformation that underlies a multi‐modal sensory role in mitochondria

open access: yesFEBS Letters, Volume 599, Issue 7, Page 971-988, April 2025.
We present the first solution structure of the Ca2+‐depleted LETM1 F‐EF‐hand through a D676A/N678A Ca2+ binding‐deficient mutant, revealing a closed hydrophobic cleft caused by a unique F1‐helix pivot. The apo LETM1 F‐EF‐hand exhibits regiospecific hot and cold unfolding, sensitivity to physiological pH changes and potential for promiscuous heterotypic
Qi‐Tong Lin   +2 more
wiley   +1 more source

Maximum tree lifespans derived from public-domain dendrochronological data

open access: yesiScience, 2023
Summary: The public-domain International Tree-Ring Data Bank (ITRDB) is an under-utilized dataset to improve existing estimates of global tree longevity.
Franco Biondi   +2 more
doaj  

METHODOLOGY OF USING MODERN APPROACHES AND INNOVATIONS IN TEACHING BIOLOGICAL SCIENCE IN UNIVERSAL EDUCATION SCHOOLS

open access: yes, 2023
This article explores the methodology and implementation of contemporary approaches and innovations in teaching biological science within the context of universal education schools. With the rapid advancements in science and technology, educators are continually seeking effective strategies to engage students and enhance their learning experiences in ...
openaire   +2 more sources

Simplified HPLC methodology for quantifying biological pterins by selective oxidation

open access: yesJournal of Chromatography B, 2017
Tetrahydrobiopterin (BH4) has become a potential therapeutic tool to treat cardiovascular diseases, since it is an essential cofactor of nitric oxide synthase. In order to quantify the amount of BH4 and its related biopterins, a procedure that involves differential oxidation is currently used, which measures biopterin (the product of the oxidation of ...
Valdes, Cristian   +3 more
openaire   +4 more sources

Exploring biological sciences preservice teachers’ sense-making of assessment feedback at a South African university. [PDF]

open access: yes, 2019
Masters Degree. University of KwaZulu-Natal, Durban.This study explored the biological sciences preservice teachers‟ understandings of assessmentfeedback.
Ngubane, Lungisani.
core  

A holistic approach to fieldwork through balanced reflective practice [PDF]

open access: yes, 2015
Reflective practice is well-established as a tool for practitioner development in areas such as nursing, social work and education. Reflection involves the integration of theoretical constructs and practical action; therefore it seems somewhat ironic ...
Blair, E., Deacon, A.
core   +2 more sources

Distinct dysregulated pathways in sporadic and Lynch syndrome‐associated colorectal cancer offer insights for targeted treatment

open access: yesFEBS Letters, Volume 599, Issue 7, Page 1006-1028, April 2025.
This study explores the distinct molecular mechanisms underlying Lynch syndrome‐associated and sporadic colorectal cancer (CRC). By highlighting the therapeutic potential of targeting the PI3K‐Akt pathway in Lynch syndrome‐associated CRC and the Wnt pathway in sporadic CRC, the findings open avenues for personalised treatment strategies, aiming to ...
May J. Krause   +2 more
wiley   +1 more source

Effects of lysate/tissue storage at −80°C on subsequently extracted EVs of epithelial ovarian cancer tissue origins

open access: yesiScience, 2023
Summary: Small extracellular vesicles (sEVs) and large extracellular vesicles (lEVs), play vital roles in intercellular communication. We optimized a method that extracts EVs from epithelial ovarian cancer (EOC) tissues for the purpose of investigating ...
Shizhen Shen   +7 more
doaj  

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