Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
El cine y la literatura de ciencia ficción como herramientas didácticas en la enseñanza de la física: una experiencia en el aula [PDF]
The aim of this work is to help to physics teachers. For this, in order to motivate students, literature and science fiction films are proposed as didactic tools.
Palacios, S.L.
doaj
Development of a benchmarking framework to assist educationists and schools on sharing strategies and application of best practices : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Engineering at Massey University, Manawatu, New Zealand [PDF]
Benchmarking is used by organisations for comparing performance and for the learning and implementation of best practices. While benchmarking remains a widely recognised improvement tool for practitioners, its application by school systems and schools ...
Malik, Rubab
core
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Sustaining induction teachers through partnerships: action research as a catalyst for change within complex contexts [PDF]
Purpose – The purpose of this action research study was to design, implement and evaluate interventions that enhanced the induction program for new teachers in a P-12 school district.
Erica Gilbertson +4 more
doaj +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
The paper considers some problems in developing techniques of ‘Literature’ teaching as a basic subject of study in the humanities for a modern Russian general academic school. The author’s view on literary centrism as a dominant idea of mental area of the Russia’s space, key constant and resource for axiological identification of Russians is given. The
openaire +1 more source
The value of a shared vision at the school of opportunity [PDF]
A thesis submitted to the School of Education, Faculty of Humanities, University of the Witwatersrand in fulfillment of the requirements of the degree of Master of Education (Leadership and Management) Johannesburg 2013This qualitative research report ...
Penrose, Julie
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source

