Results 61 to 70 of about 574,865 (264)

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Leitura de contos no ensino fundamental: a contribuição da Teoria Literária nesse processo

open access: yesDiálogo das Letras, 2013
We propose, through a literature review and considerations of praxis developed in the classroom, investigate how literary theory contributes to the reading practices of short stories in elementary school.
Luciéle Bernardi de Souza   +1 more
doaj  

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

Text and image

open access: yesФилологический класс, 2004
The author of the article discusses the category of "artistry", which often denotes the text.
doaj  

COUNSELLING NEEDS OF HIGH SCHOOL STUDENTS: EXPLORING TEACHERS’ PERSPECTIVE

open access: yesPakistan Armed Forces Medical Journal, 2020
Objective: The limitations for incorporating the counseling services as an institutional mechanism at school level have gained recent attention in the context of Pakistan.
Aneela Maqsood   +2 more
doaj  

PSYCHODYNAMIC PROTOTYPE THROUGH PERSONALITY ORGANIZATION CHART OF EDUCATIONAL LEADERS

open access: yesAnthropological Researches and Studies, 2018
Objectives. The present study aims to explore the problematic situation of Personality Organization and Behavioral Tendency in the target group of school leaders and to highlight the need of a qualitative change and organizational structures of the ...
Silva Ibrahimi   +3 more
doaj   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Development of Motor Coordination Abilities in Children of Primary School Age with Mental Retardation: an Integrated Approach

open access: yesФизическая культура. Спорт. Туризм. Двигательная рекреация, 2019
The article presents the methodology for the development of motor coordination abilities of primary school age children with a mild mental retardation based on an integrated approach implying the gradual development of motor coordination abilities ...
Kalmykov D.A.
doaj   +1 more source

Methodological Evaluation of Secondary School Systems in Kenya: A Systematic Literature Review of Randomized Field Trials

open access: yes, 2005
Methodological evaluation of secondary school systems in Kenya is crucial for understanding their effectiveness and identifying areas for improvement. A comprehensive search strategy was employed using multiple databases, including PubMed and Web of Science, with predefined inclusion criteria based on randomized field trials conducted in Kenya between ...
Githae, Korogocho   +3 more
openaire   +2 more sources

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

open access: yesAging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel   +4 more
wiley   +1 more source

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