Results 91 to 100 of about 2,753,696 (263)

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

open access: yesFEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés   +2 more
wiley   +1 more source

Flax Fibre Extraction Techniques in the Late Middle Ages

open access: yesEXARC Journal, 2020
On its surface, linen production research is simple as there is a large corpus of books available; however, the majority of these date to the last three centuries.
Martina König
doaj  

Comparing the paths of Hedgehog release in artificial and natural settings

open access: yesFEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

A Missing Link in the Chaîne Opératoire

open access: yesEXARC Journal
How elitist attitudes shape archaeological interpretations. A curious misunderstanding arose while writing about Bronze Age metalworking hearths and smiths.
E. Giovanna Fregni
doaj  

Let the Chips Fall Where They May: Evaluating the Impact and Effectiveness of Video Resources for Knowledge Transfer in Flint Knapping

open access: yesEXARC Journal, 2020
Knowledge and know-how: The ‘how’ of knowledge transferal continues to be a question in prehistoric archaeology, especially in relation to early hominid development.
John Kiernan
doaj  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Post-mastectomy Breast Reconstruction with Autologous Tissue: Current Methods and Techniques. [PDF]

open access: yesPlast Reconstr Surg Glob Open, 2021
Garza R, Ochoa O, Chrysopoulo M.
europepmc   +1 more source

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