Results 101 to 110 of about 896,359 (265)

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Comparing the Effect of Concept Mapping to Clinical Simulation on Emergency Medical Students` Clinical Decision Making [PDF]

مجله ایرانی آموزش در علوم پزشکی, 2014
Introduction: Application of appropriate teaching techniques can increase decision-making skills in emergency settings. Considering the importance of decision-making for rescuers in prevention of deteriorating problems and maintaining patient’s safety in
Hossein Sadeghnezhad, Thayebe Khazaei, Ahmad Nasiri   +2 more
doaj  

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Uncertainty in tuberculosis clinical decision-making: An umbrella review with systematic methods and thematic analysis

PLOS Global Public Health
Tuberculosis is a major infectious disease worldwide, but currently available diagnostics have suboptimal accuracy, particularly in patients unable to expectorate, and are often unavailable at the point-of-care in resource-limited settings. Test/treatment decision are, therefore, often made on clinical grounds.
Basile, FW, Sweeney, S, Singh, MP, Bijker, EM, Cohen, T, Menzies, NA, Vassall, A, Indravudh, P   +7 more
openaire   +4 more sources

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Mixed methods evaluation of megacode simulation training to enhance clinical reasoning and decision making in critical care nursing

Educación Médica
Background: Effective clinical judgment is essential for critical care nursing, yet few studies have comprehensively examined how simulation training impacts both technical and cognitive development.
Rudena A. Madayag, Christian Leandro Monieno, Jonel Mallari, Angela Apostol, Evangeline Bautista, Rei Angelo Mangibin, Dennison Jose Punsalan, Isabelito Nabong   +7 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Relationship Between Nursing Students’ Professional Values and Their Perceptions of Clinical Decision-Making: A Cross-Sectional Study

Sakarya Üniversitesi Holistik Sağlık Dergisi
Objective: The present study aimed to investigate the relationship between nursing students' professional values and their perceptions of clinical decision-making.Methods: This descriptive, cross-sectional, correlational study included 207 nursing ...
Hürmüs Kuzgun
doaj   +1 more source

Unlocking Patient Preferences: The Potential of Stated-Preference Methods in Clinical Decision Making

Value in Health
Stated-preference (SP) methods are gaining attention as tools to support patient-centered clinical decision making by quantifying individual preferences through structured tradeoffs. These methods may improve shared decision making by helping patients and clinicians better understand the relative importance of treatment attributes and the trade-offs ...
Ozdemir, Semra, Veldwijk, Jorien, van Til, Janine, Hollin, Ilene L., Marshall, Deborah A., Reed, Shelby D.   +5 more
openaire   +3 more sources