Results 21 to 30 of about 2,552 (122)

The Traditional Chinese Medicine Compound Hezi Qingyou Formula Controls the MAPK Signaling Pathway for Alleviating Gastric Ulcer Induced by Acetic Acid in Rats

Journal of Immunology Research, Volume 2026, Issue 1, 2026.
In clinical practice, Hezi Qingyou Formula (HZQYF) has been observed to effectively alleviate clinical symptoms associated with gastri ulcers, though its precise mechanism of action remains unclear. To investigate the effects of HZQYF on gastric ulcers, we established a rat model of gastric ulcer and examined its impact on ulcer area, pathological ...
Zhong Feng, Ruixia Wei, Junhao Tian, Hui Li, Haobo Chen, Yajie Hao, Meiyun Chen, Bingmei Su, Yuqian Lai, Mingjin Xun, Guimin Zhang, Meicun Yao, Poorani Gurumallesh   +12 more
wiley   +1 more source

Seminars in epileptology: Presurgical epilepsy evaluation

Epileptic Disorders, Volume 27, Issue 6, Page 1105-1147, December 2025.
Abstract All patients with drug‐resistant seizures benefit from a comprehensive evaluation to confirm their seizure diagnosis and explore surgical treatment options. This seminar in epileptology discusses advancements in the field and provides specific didactic material to create an active working knowledge for the care of patients with focal drug ...
Stephan Schuele, Robyn M. Busch, Birgit Frauscher, Vadym Gnatkovsky, Hajo Hamer, Lara Jehi, Andres Kanner, Georgia Ramantani, Theodor Rüber, Andreas Schulze‐Bonhage, Rainer Surges, Lara Wadi   +11 more
wiley   +1 more source

Diagnostic Challenges in the Neuropsychology of Epilepsy: Report of the ILAE Neuropsychology Task Force Diagnostic Methods Commission: 2021–2025

Epileptic Disorders, Volume 27, Issue 5, Page 729-744, October 2025.
Abstract Increasingly, it has been recognized that non‐seizure‐related factors influence how people with epilepsy perform on neuropsychological tests. Therefore, neuropsychologists need to recognize the constellation of factors that can contribute to the neurocognitive presentation of a person with epilepsy and consider these factors in the ...
Mary Lou Smith, Mayu Fujikawa, Genevieve Rayner, Seth A. Margolis, Bruce Hermann, Gus Baker, Sallie Baxendale, Robyn Busch, Aimee Dollman, Vicki Ives‐Deliperi, Carrie R. McDonald, Urvashi Shah, Sarah Wilson   +12 more
wiley   +1 more source

Presbycusis: Pathology, Signal Pathways, and Therapeutic Strategy

Advanced Science, Volume 12, Issue 29, August 7, 2025.
In ARHL, the stria vascularis, acting as a cochlear battery, gradually loses its ability to maintain the endocochlear potential, leading to impaired hair cell function and progressive hearing loss. Single‐cell sequencing reveals age‐related cellular changes in the cochlea, providing insights into the underlying mechanisms of aging and potential ...
Xiaoxu Zhao, Tian Shen, Shengda Cao, Ziyi Liu, Wendu Pang, Meixuan Li, Jingjing Liu, Wen Li, Yunhao Wu, Chengcheng Liu, Ming Xia, Xiaolong Fu, Cheng Cheng   +12 more
wiley   +1 more source

Rapid sequence induction – high demand on narcotics Comparison of depth of anesthesia from methohexital, propofol and edomidate with CSM™

, 2013
Hintergrund: Bei der Einleitung einer Narkose eines nicht-nüchternen Patienten wird das Relaxanz in unmittelbarer Folge zum Induktionsmittel appliziert.
Schlembach, Jana
core   +2 more sources

The human photosensitive epilepsy model for clinical proof‐of‐principle trials of novel antiseizure medications: 2. Analysis of drug trials and predictive value of the model

Epilepsia, Volume 66, Issue 8, Page 2619-2638, August 2025.
Abstract Clinical development of novel antiseizure medications (ASMs) would benefit from an early proof of principle (POP) model. The photosensitivity model, which uses the photoparoxysmal electroencephalographic response (PPR) as a surrogate of seizures, is currently the only human model that allows POP trials of investigational compounds after a ...
Wolfgang Löscher, Dorothée Kasteleijn‐Nolst Trenité   +1 more
wiley   +1 more source

Effects of Anesthesia Changes During Maintenance ECT: A Longitudinal Comparison of Seizure Quality Under Anesthesia Using Propofol/Esketamine Versus Methohexital

, 2023
Introduction The effectiveness of ECT relies on the induction of a generalized cerebral seizure. Among others, seizure quality (SQ) is potentially influenced by the anesthetic drug used.
Belz, Michael, Isabel Methfessel, David Zilles-Wegner, Nils Kunze-Szikszay, Methfessel, Isabel, Zilles-Wegner, David, Kunze-Szikszay, Nils, Michael Belz   +7 more
core   +1 more source

α‐Azaaryl carbonyl derivatives in stereodivergent catalytic reactions

Bulletin of the Korean Chemical Society, Volume 46, Issue 6, Page 602-621, June 2025.
This review highlights recent progress in the catalytic synthesis of chiral azaarenes, focusing on α‐azaaryl carbonyl derivatives as versatile precursors. By leveraging chiral Lewis acid catalysis, stereodivergent reactions with diverse electrophiles enable precise construction of multi‐stereogenic azaarenes, offering new opportunities for advanced ...
Ilwoo Song, Byungjun Kim, Hooseung Lee, Sarah Yunmi Lee   +3 more
wiley   +1 more source

Dual ETA‐ETB receptor antagonism improves metabolic syndrome‐induced heart failure with preserved ejection fraction

Fundamental &Clinical Pharmacology, Volume 39, Issue 3, June 2025.
Abstract Background Metabolic syndrome (MetS) is a multifaceted disease associated with heart failure (HF), which affects the vascular system. The endothelin (ET) system is a key player in MetS and HF; therefore, targets for ET receptors are of therapeutic interest.
Francesca Lockwood, Marianne Lachaux, Najah Harouki, Matthieu Soulié, Lionel Nicol, Sylvanie Renet, Anaïs Dumesnil, Magali Vercauteren, Jeremy Bellien, Marc Iglarz, Vincent Richard, Paul Mulder   +11 more
wiley   +1 more source

Our experience with the intracarotid methohexital procedure

, 2009
Purpose: In this retrospective study we report our 3 years of experience of the intracarotid methohexital test. Materials and Methods: Fifty-two candidates for epilepsy surgery underwent the intracarond methohexital procedure (IMP; also known as the Wada
ILGIT, ERHAN TURGUT, Koçer, Belgin, Soysal, Sebnem, SERDAROĞLU, AYŞE, Aktürk, Aysima, ARHAN, EBRU, Bilir, Erhan, Önal, Baran   +7 more
core   +1 more source