Results 41 to 50 of about 3,512 (157)
Fundamental &Clinical Pharmacology, Volume 39, Issue 3, June 2025.Abstract Background Metabolic syndrome (MetS) is a multifaceted disease associated with heart failure (HF), which affects the vascular system. The endothelin (ET) system is a key player in MetS and HF; therefore, targets for ET receptors are of therapeutic interest.
Francesca Lockwood +11 more
wiley +1 more source
Ascorbic acid prevents cimetidine-induced decrease of serum hydrocortisone concentrations [PDF]
, 1990 A blind, parallel, prospective, clinical study was conducted to investigate the effect of ascorbic acid on human serum hydrocortisone concentrations which were decreased by the administration of cimetidine.
Boidin, M.P. (Marinus Pieter) +2 more
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Clinical Pharmacology &Therapeutics, Volume 117, Issue 2, Page 374-386, February 2025.Ketamine has a long and very eventful pharmacological history. Its enantiomer, esketamine ((S)‐ketamine), was approved by the US Food and Drug Administration (FDA) and EMA for patients with treatment‐resistant depression (TRD) in 2019. The number of approved indications for ketamine and esketamine continues to increase, as well as the number of ...
Ksenia A. Vekhova +3 more
wiley +1 more source
Histamine release after intravenous application of short-acting hypnotics. A comparison of etomidate, Althesin (CT1341) and propanidid [PDF]
, 1973 The subject of histamine release was investigated in 16 volunteers by means of plasma histamine determination after the administration of etornidate, Althesin, propanidid, and Cremophor EL.
Beigl, R. +7 more
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Involvement of the peripheral sensory and sympathetic nervous system in the vascular endothelial expression of ICAM-1 and the recruitment of opioid containing immune cells to inhibit inflammatory pain [PDF]
, 2012 Endogene Opioidpeptide können in bestimmten Regionen des Gehirns als Antwort auf Stress-Stimuli freigesetzt werden. Kürzlich wurden Leukozyten als zusätzliche Quelle endogener Opioide nachgewiesen.
Brendl, Ute
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Pain Research and Management, Volume 2025, Issue 1, 2025.General anaesthesia (GA) as a pharmacological behaviour management strategy may be indicated for dental extractions in children unable to cooperate in the dental chair. Pain is the most common postoperative complication in children following dental GA.
Emily Xin Yi Ting +4 more
wiley +1 more source
Acta Paediatrica, Volume 113, Issue 11, Page 2363-2377, November 2024.Abstract Aim Management of primary healthcare and routine minor procedures for children with autism spectrum disorder (ASD) can be challenging; therefore, when behavioural strategies fail, sedative medications are often employed. We evaluated the effectiveness of the current pharmacological strategies for managing children with ASD.
Luisa Zupin +6 more
wiley +1 more source
Connections of the Mesencephalic Locomotor Region (MLR) in the Cat [PDF]
, 1980 The cat entopeduncular nucleus (EN), which is the main output of the basal ganglia, is known to project to the mesencephalic tegmentum. We have been able to elicit antidromic responses in single EN neurons from the region of the mesencephalic locomotor ...
Garcia-Rill, E. +2 more
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Addiction Biology, Volume 29, Issue 8, August 2024.Oxycodone seeking was higher in females following SNI that came after the 10‐day SA timeline. A selective increase in dorsomedial prefrontal cortex pyramidal cell intrinsic excitability was detected among non‐ensemble neurons from female mice that self‐administered oxycodone and received SNI.
Bailey C. Sarka +5 more
wiley +1 more source
Effect of naloxone on seizure duration after electroshock therapy (ECT [PDF]
, 2004 ECT is a process in which a generalized seizure is induced by passing electrical current for 25 to 150 seconds through the brain under general anesthesia. It is a highly effective treatment for major depression, mania and schizophrenia.
Abedinzadeh, Mohammadreza. +3 more
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