Results 101 to 110 of about 245,199 (308)

Real‐world trends in prenatal antirheumatic drug utilization in Ontario, Canada: A cross‐sectional time‐series analysis

Arthritis Care &Research, Accepted Article.
Objectives This study aimed to describe real‐world trends in preconception and prenatal use of antirheumatic drugs among pregnant individuals with rheumatic diseases in Ontario, Canada. Methods We conducted a time‐series analysis using repeated cross‐sectional data to examine annual patterns of disease‐modifying antirheumatic drug (DMARD) use among ...
Shenthuraan Tharmarajah, Swaleh Hussain, Sara J.T. Guilcher, Lisa M. McCarthy, Dharini Mahendira, Howard Berger, Mina Tadrous   +6 more
wiley   +1 more source

Single Dose Methotrexate in Treatment of Ectopic Pregnancy: Review of 32 Case

Balkan Medical Journal, 2011
Objective: To evaluate the efficacy of single dose intramuscular methotrexate in the treatment of ectopic pregnancy.Material and Methods: 32 patients who matched the inclusion criteria were enrolled.
Aysun Aybatlı, Petek Balkanlı Kaplan, Mehmet Alicik, Niyazi Cenk Sayın, Mehmet Ali Yüce   +4 more
doaj  

Comparing the effectiveness and drug persistence of methotrexate, cyclosporine, and acitretin for psoriasis

International Journal of Women's Dermatology
Background:. Conventional systemic agents remain the cornerstone treatment for psoriasis because of their availability and cost-effectiveness. However, few studies have compared the effectiveness and drug persistence of these agents in Asian populations.
Chayada Chaiyabutr, MD, Teerapat Paringkarn, MD, Narumol Silpa-archa, MD, Chanisada Wongpraprarut, MD, Leena Chularojanamontri, MD   +4 more
doaj   +1 more source

Methotrexate Exposure and Risk of Cutaneous Malignant Melanoma: No Evidence of a Dose-response Relationship

Acta Dermato-Venereologica, 2018
Methotrexate treatment has been linked with an increased risk of melanoma. However, a possible dose-response relationship with respect to methotrexate exposure and melanoma has not been addressed.
Sam Polesie, Martin Gillstedt, John Paoli, Amra Osmancevic   +3 more
doaj   +1 more source

Effects of the anti-RANKL antibody denosumab on joint structural damage in patients with rheumatoid arthritis treated with conventional synthetic disease-modifying antirheumatic drugs (DESIRABLE study): a randomised, double-blind, placebo-controlled phase 3 trial. [PDF]

, 2019
ObjectiveTo evaluate the efficacy of denosumab in suppressing joint destruction when added to conventional synthetic disease-modifying antirheumatic drug (csDMARD) therapy in patients with rheumatoid arthritis (RA).MethodsThis was a multi-centre ...
Genant, Harry K, Nitta, Takaya, Okubo, Naoki, Soen, Satoshi, Takeuchi, Tsutomu, Tanaka, Sakae, Tanaka, Yoshiya, van der Heijde, Désirée, Yamanaka, Hisashi, Yoneda, Toshiyuki   +9 more
core   +2 more sources

Consumed by Abdominal Distention

Arthritis Care &Research, EarlyView.
Abimbola Fadairo‐Azinge, James Grenert, Brian Haas, Mary Margaretten   +3 more
wiley   +1 more source

Light Activated Induction of Cuproptosis in Resistant Cancer Cells Using Polymeric BODIPY Nanoparticles for Photoactivated Chemotherapy

Advanced Functional Materials, EarlyView.
This article presents a photo‐responsive nanoparticle platform that precisely triggers copper‐dependent cuproptotic cell death in (drug‐resistant) cancer cells. The system remains stable and inactive in the dark but releases cytotoxic species upon red‐light irradiation, achieving potent activity in drug‐resistant breast cancer cells.
Ricarda Zimmermann, Nicolás Montesdeoca, Johannes Karges   +2 more
wiley   +1 more source

Predictors Associated with Delayed Methotrexate Clearance among Patients with Haematological Malignancies

Journal of Pharmacy
Introduction: High dose methotrexate is commonly utilised in haematological malignancies; however, the prevalence of delayed clearance is not well-defined.
Muhammad Nasri Yusoff, Noraida Mohamed Shah, Nor Asyikin Mohd Tahir, Sakina Nur Najah Abdul Jabar, Ahlam Naila Kori, Nor Rafeah Tumian   +5 more
doaj  

Efficacy And Safety Of Methotrexate In Psoriasis A Reappraisal

Indian Journal of Dermatology, 2000
Fifty five patients of extensive psoriasis were treated with oral weekly methotrexate. All patients responded promptly to methotrexate therapy. Relapse was observed after variable periods following stoppage of methotrexate.
Kanwar Amrinder J, Jaswal Ritu, Thami Gurvinder P   +2 more
doaj  

Accidental Chronic Poisoning with Methotrexate; Report of Two Cases

Archives of Academic Emergency Medicine, 2016
Methotrexate has been used widely in dermatology, oncology and rheumatology fields. However, methotrexate-induced mucocutaneous lesions may occur in rare cases.
Reza Bidaki, Mojgan Kian, Hamid Owliaey, Mojtaba Babaei Zarch, Masoud Feysal   +4 more
doaj   +1 more source