Update on subcutaneous methotrexate for inflammatory arthritis and psoriasis
Gino Antonio Vena,1,2 Nicoletta Cassano,1,2 Florenzo Iannone3 1Dermatology and Venereology Private Practice, Bari, 2Dermatology and Venereology Private Practice, Barletta, 3Department of Emergency and Organ Transplantation, Rheumatology Unit, University
Iannone F, Vena GA, Cassano N
core
Objective To assess the association between duration of targeted therapy exposure and cancer risk in patients with spondyloarthritis (SpA), including those with psoriatic arthritis, axial SpA, and other subtypes. Methods This nationwide cohort study used the French health insurance database to identify adults with SpA initiating a targeted therapy ...
Karine Tankovic +7 more
wiley +1 more source
A Case Report of a 64-Year-Old Man With Urothelial Carcinoma With Brain and Leptomeningeal Metastases Treated With Intrathecal Methotrexate as Part of Multimodal Management. [PDF]
Damron LF +11 more
europepmc +1 more source
Cancer in Systemic Sclerosis: Clinical Associations and Prognostic Impact From the EUSTAR Registry
Objective Cancer represents a major cause of death in systemic sclerosis (SSc). Established risk factors are limited to specific subsets, particularly early diffuse anti‐RNA polymerase III (POLR3)–positive disease, needing further exploration. Methods We performed a nested case‐control study within the European Scleroderma Trials and Research group ...
Antonio Tonutti +52 more
wiley +1 more source
AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
Hepatology, EarlyView.
Robert J. Fontana +6 more
wiley +1 more source
Effectiveness of single-dose methotrexate in the treatment of ectopic pregnancy: a retrospective study. [PDF]
Mendonça LP, da Fonseca EC.
europepmc +1 more source
Human Monocytic Models Reveal Genotype‐Dependent Inflammatory Programs in VEXAS Syndrome
Objectives VEXAS syndrome is a severe X‐linked autoinflammatory disorder caused by somatic mutations in ubiquitin‐like modifier activating enzyme 1 (UBA1), with clinical outcomes that vary by UBA1 genotype. We aimed to elucidate genotype‐specific inflammatory programs and identify potential therapeutic targets.
Kana Higashitani +10 more
wiley +1 more source
Attitudes of healthcare professionals towards the use of parenteral methotrexate in rheumatoid arthritis patients: a qualitative study. [PDF]
Tan JM +5 more
europepmc +1 more source
Expert Perspective: Toward Treat‐to‐Target Management in Adult Idiopathic Inflammatory Myopathies
Treat‐to‐target (T2T) has transformed the management of several rheumatic diseases through predefined therapeutic goals, structured disease assessment, and timely treatment adjustment. Despite major advances in the understanding and treatment of idiopathic inflammatory myopathies (IIM), a formal T2T framework for adult IIM has not yet been established.
Shiri Keret +2 more
wiley +1 more source
Psoriasis and chronic kidney disease: a systemic inflammatory link and a practical kidney assessment pathway. [PDF]
Almeida-Silva G +6 more
europepmc +1 more source

