Results 291 to 300 of about 369,868 (397)

Maintenance of Carnitine Homeostasis as a Therapeutic Strategy to Attenuate Cisplatin‐Induced Acute Kidney Injury

open access: yesFood Frontiers, EarlyView.
ABSTRACT Acute kidney injury (AKI) has emerged as a significant global public health concern due to its high morbidity and mortality rates. Cisplatin, a highly effective and widely used chemotherapeutic agent, is often limited in clinical application by its nephrotoxicity, particularly AKI.
Mingkang Zhang   +5 more
wiley   +1 more source

Tumor‐infiltrating B cells participate in shaping the immunosuppressive microenvironment in solid tumors

open access: yesInternational Journal of Cancer, EarlyView.
Abstract Tumor‐infiltrating B cells (TIBs) exhibit dual roles in the tumor microenvironment (TME) of solid tumors. While they can enhance anti‐tumor immunity through antibody production and immune activation, certain subsets—such as regulatory B cells (Bregs) and immunosuppressive plasma cells—contribute to immune evasion by secreting inhibitory ...
Zhitong Li   +5 more
wiley   +1 more source

Progesterone receptor (PR) intra‐tumor heterogeneity in premenopausal breast cancer: A secondary analysis of a randomized trial

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Progesterone receptor (PR) expression in breast cancer is influenced by menopausal status and PR positivity is more common in premenopausal women. The influence of PR intra‐tumor heterogeneity on distant recurrence risk in premenopausal women, however, remains unknown. In this investigation, variations in PR expression within breast tumors,
Oscar Danielsson   +13 more
wiley   +1 more source

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