Results 41 to 50 of about 2,064 (176)

Investigation of the Regulatory Mechanism of Huazhuo Runzao Jiangqi Formula on Esophageal Cancer Utilizing Network Pharmacology, Molecular Docking, and In Vivo and In Vitro Experiments

International Journal of Genomics, Volume 2026, Issue 1, 2026.
Background Esophageal cancer, a common digestive malignant neoplasm globally, poses significant health risks. Huazhuo Runzao Jiangqi (HRJ) formula, modified from the classic “Qige Powder” with additions and reductions, has shown clear efficacy in treating esophageal cancer and precancerous lesions in clinical practice and preliminary studies ...
Yun He, Huan-Fang Fan, De-Hui Li, Zi-Hui Liu, Yi-Ting Gu, Chang-Hui Han, Pan Ma, Na Guo, Xiao Wang, Yan Han, Irfan Ahmad   +10 more
wiley   +1 more source

Extraction, Isolation, and Purification of Furanocoumarins from Invasive Heracleum sosnowskyi

Separations
Heracleum sosnowskyi Manden. (Sosnowsky’s hogweed), originally introduced to Central and Eastern Europe as a fodder crop, has become a highly invasive species due to its ecological adaptability, high reproductive capacity, and efficient seed dispersal ...
Vida Vickackaite, Karina Pilaityte, Vilius Poskus   +2 more
doaj   +1 more source

Citrus Consumption and Risk of Basal Cell Carcinoma and Squamous Cell Carcinoma of the Skin [PDF]

, 2015
Animal experiments have demonstrated the photocarcinogenic properties of furocoumarins, a group of naturally occurring chemicals that are rich in citrus products.
Cho, Eunyoung, Feskanich, Diane, Han, Jiali, Li, Wen-Qing, Qureshi, Abrar A., Sun, Qi, Wu, Shaowei   +6 more
core   +1 more source

Exposure Registries as a Prevention Tool for Occupational Cancers: Establishing a New Hazardous Drug Registry for Oncology Personnel

American Journal of Industrial Medicine, Volume 68, Issue 12, Page 1037-1047, December 2025.
ABSTRACT Public health registries collect and maintain demographic and health data on a cohort of people with a common disease or exposure. While disease registries have proliferated in recent decades, registries comprising persons with potentially hazardous exposures—known commonly as exposure registries—are rare.
Sammy Almashat, Matthew Horch, Brian Chen, Melissa McDiarmid   +3 more
wiley   +1 more source

Drugs and drug-like molecules can modulate the function of mucosal-associated invariant T cells [PDF]

, 2017
The major-histocompatibility-complex-(MHC)-class-I-related molecule MR1 can present activating and non-activating vitamin-B-based ligands to mucosal-associated invariant T cells (MAIT cells). Whether MR1 binds other ligands is unknown. Here we identified
A Kurioka, AJ Corbett, AJ McCoy, AL Szymczak, Alexandra J Corbett, Andrew N Keller, Anthony W Purcell, Bronwyn S Meehan, BY Chua, Criselle D'Souza, Dale I Godfrey, David P Fairlie, DC Chatterji, DI Godfrey, E Treiner, EY Jones, F Koning, F Tilloy, HEG McWilliam, Huimeng Wang, I Kawachi, I Van Rhijn, IJ Skypala, James McCluskey, Jamie Rossjohn, JE Ussher, Jeffrey Y W Mak, L Kjer-Nielsen, L Le Bourhis, Lars Kjer-Nielsen, Ligong Liu, Lyudmila Kostenko, M Bharadwaj, M Dusseaux, M Lepore, M Salio, MC Gold, MD Winn, MHM Heemskerk, NA Gherardin, Nicholas A Gherardin, NM Davies, O Patel, P Emsley, PCD Hawkins, PD Adams, PF Fehlner, PJ Hashkes, PT Illing, R Reantragoon, R Reantragoon, Richard W Birkinshaw, S Gras, S Gras, S Huang, S Zelcer, SB Eckle, SB Eckle, Sidonia B G Eckle, SK Hoiseth, Troi Pediongco, V Krasniqi, VB Chen, VC Romão, Victoria A Hughes, Weijun Xu, WXDS Kabsch, Zhenjun Chen   +67 more
core   +2 more sources

Pluripotent stem cell-derived hepatocyte-like cells [PDF]

, 2014
Liver disease is an important clinical problem, impacting over 30 million Americans and over 600 million people worldwide. It is the 12th leading cause of death in the United States and the 16th worldwide.
Bhatia, Sangeeta N, Fleming, Heather, Khetani, Salman R., Schwartz, Robert E.   +3 more
core   +1 more source

Melanocyte transplantation to skin prepared by controlled PUVA-induced sunburn-like blistering for vitiligo treatment – A pilot clinical trial

Journal of the Formosan Medical Association
Vitiligo is a common acquired disease of pigment loss. In lesions recalcitrant to non-invasive treatment, transplantation of cultured autologous melanocytes is an emerging choice.
Po-Hua Chen, Sabrina Mai-Yi Fan, Bin-Ru She, Yi-Ping Wu, Hsiang-Chun Hsu, Ying-Jung Yang, Jun-Jae Huang, Shu-Fen Yeh, Yi-Chen Chen, Pei-Ju Lin, Wann-Hsin Chen, Hsien-Ching Chiu, Hsin-Su Yu, Chih-Ching Liao, Sung-Jan Lin   +14 more
doaj   +1 more source

Recovering actives in multi-antitarget and target design of analogs of the myosin II inhibitor blebbistatin [PDF]

, 2018
In multitarget drug design, it is critical to identify active and inactive compounds against a variety of targets and antitargets. Multitarget strategies thus test the limits of available technology, be that in screening large databases of compounds vs a
García-Sosa, Alfonso T, Guedes, Rita C, Roman, Bart, Stevens, Christian   +3 more
core   +2 more sources

The Concise Guide to PHARMACOLOGY 2025/26: G protein‐coupled receptors

British Journal of Pharmacology, Volume 182, Issue S1, Page S24-S151, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander, Anthony P. Davenport, Eamonn Kelly, Alasdair J. Gibb, Alistair A. Mathie, Chloe J. Peach, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Christopher Southan, Jamie A. Davies, Maria Pia Abbracchio, George R. Abraham, Alexander Agoulnik, Wayne Alexander, Khaled Al‐hosaini, Magnus Bäck, Jillian G. Baker, Nicholas M. Barnes, Ross Bathgate, Jean‐Martin Beaulieu, Annette G. Beck‐Sickinger, Maik Behrens, Kirstie A. Bennett, Kenneth E. Bernstein, Bernhard Bettler, Nigel J. M. Birdsall, Victoria A. Blaho, Pascal Bonaventure, Francois Boulay, Corinne Bousquet, Hans Bräuner‐Osborne, Andrew J. Brown, Geoffrey Burnstock, Marta Busnelli, Girolamo Caló, Vanni Caruso, Justo P. Castaño, Kevin J. Catt, Stefania Ceruti, Paul Chazot, Nan Chiang, Bice Chini, Arthur Christopoulos, Jerold Chun, Antonia Cianciulli, Olivier Civelli, Lucie H. Clapp, Réjean Couture, Helen M. Cox, Zsolt Csaba, Claes Dahlgren, Frank M. Dautzenberg, Gordon Dent, Steven D. Douglas, Pascal Dournaud, Margarita L. Dubocovich, Satoru Eguchi, Emanuel Escher, Edward J. Filardo, Tung Fong, Huamei Fu Forsman, Marta Fumagalli, Raul R. Gainetdinov, Michael L. Garelja, Marc de Gasparo, Florence Gbahou, Craig Gerard, Marvin Gershengorn, Michelle Glass, David E. Gloriam, Fernand Gobeil, Theodore L. Goodfriend, Cyril Goudet, Lukas Grätz, Karen J. Gregory, Christian Gruber, Andrew L. Gundlach, Jörg Hamann, Julien Hanson, Deborah S. Hartman, Richard L. Hauger, Debbie L. Hay, Akos Heinemann, Laura Heitman, Deron R. Herr, Morley D. Hollenberg, Nicholas D. Holliday, Birgitte Holst, Mastgugu Horiuchi, Daniel Hoyer, László Hunyady, Ahsan Husain, Adriaan P. IJzerman, Tadashi Inagami, Paul A. Insel, Kenneth A. Jacobson, Laura H. Jacobson, Robert T. Jensen, Ralf Jockers, Deepa Jonnalagadda, Sadashiva Karnik, Klemens Kaupmann, Jacqueline Kemp, Charles Kennedy, Yasuyuki Kihara, Julia Kinsolving, Takio Kitazawa, Pawel Kozielewicz, Hans‐Jürgen Kreienkamp, Jyrki P. Kukkonen, Luxmichan Laishram, Tobias Langenhan, Christopher J. Langmead, Dan Larhammar, Katie Leach, Davide Lecca, John D. Lee, Susan E. Leeman, Jérôme Leprince, Rob Leurs, Xaria X. Li, Ines Liebscher, Stephen J. Lolait, Amelie Lupp, Robyn Macrae, Janet J. Maguire, Davide Malfacini, Maurice Manning, Davide Marangon, Kirill Martemyanov, Jean Mazella, Craig A. McArdle, Shlomo Melmed, Martin C. Michel, Laurence J. Miller, Vincenzo Mitolo, Bernard Mouillac, Christa E. Müller, Philip M. Murphy, Jean‐Louis Nahon, Richard R. Neubig, Tony Ngo, Xavier Norel, Duuamene Nyimanu, Anne‐Marie O’Carroll, Stefan Offermanns, Maria Antonietta Panaro, Marc Parmentier, Nicole Perry‐Hauser, Roger G. Pertwee, Jean‐Philippe Pin, Eric R. Prossnitz, Helena Chengxue Qin, Mark Quinn, Stefano Raffaele, Rithwik Ramachandran, Manisha Ray, Rainer K. Reinscheid, Alejandro Romeral Buzón, Philippe Rondard, Mette M. Rosenkilde, G. Enrico Rovati, Chiara Ruzza, Gareth J. Sanger, Nicole Scholz, Torsten Schöneberg, Gunnar Schulte, Stefan Schulz, Deborah L. Segaloff, Charles N. Serhan, Arun K. Shukla, Khuraijam Dhanachandra Singh, Craig M. Smith, Nicola J. Smith, Claudia Stäubert, Leigh A. Stoddart, Yukihiko Sugimoto, Roger Summers, Valerie P. Tan, David M. Thal, Walter ( Wally) Thomas, Pieter B. M. W. M. Timmermans, Kalyan Tirupula, Lawrence Toll, Giovanni Tulipano, Hamiyet Unal, Thomas Unger, Celine Valant, Patrick Vanderheyden, David Vaudry, Hubert Vaudry, Joseph G. Verbalis, Jean‐Pierre Vilardaga, Christopher S. Walker, Ji Ming Wang, Donald T. Ward, Hans‐Jürgen Wester, Gary B. Willars, Tom Lloyd Williams, Trent M. Woodruff, Huixian Wu, Cheng Yang, Chengcan Yao, Richard D. Ye, Nathan Zaidman   +206 more
wiley   +1 more source

Breast and Nipple Dermatoses During Lactation

Australasian Journal of Dermatology, Volume 66, Issue 7, Page e386-e407, November 2025.
ABSTRACT Lactation and breastfeeding can present both psychological and physical challenges for breastfeeding mothers. In addition, many nursing mothers will also suffer from breast and nipple dermatoses during this period, compounding these difficulties. Common causes of breast and nipple dermatitis during lactation include eczema, psoriasis, mastitis,
Hamish Moore, Annabel Stevenson
wiley   +1 more source