Results 41 to 50 of about 1,995 (182)
Background: Vitiligo is a common acquired disorder of skin depigmentation in varying patterns, varying from small maculae’s with scalloping borders to near total depigmentation of body.
P. Khan
semanticscholar +1 more source
A Mild Disilane‐Enabled Halide‐to‐Deuterium Manifold With D2O for Aryl and Benzylic Halides
A broadly applicable Pd‐catalyzed dehalogenative deuteration enables efficient conversion of aryl and benzylic halides with inexpensive deuterium oxide (D2O). The method proceeds under exceptionally mild conditions without strong bases, harsh reductants, or stoichiometric Lewis acid halide scavengers, and tolerates a wide range of functional groups ...
Wenliang Wang +5 more
wiley +1 more source
Methoxsalen loaded chitosan coated microemulsion for effective treatment of psoriasis [PDF]
Methoxsalen has been used for the treatment of psoriasis. In order to develop alternative formulations for the topical administration of methoxsalen, chitosan coated microemulsion were evaluated as delivery vehicle.
Yadav, Arvind; SLT Institute of Pharmaceutical Sciences, Guru Ghasi Das University, Bilaspur, C.G., 495009 India +4 more
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Methoxsalen loaded chitosan coated microemulsion for effective treatment of psoriasis [PDF]
Methoxsalen has been used for the treatment of psoriasis. In order to develop alternative formulations for the topical administration of methoxsalen, chitosan coated microemulsion were evaluated as delivery vehicle.
Anoop Chadoker +4 more
core
The pharmacokinetic interaction between cyclosporine and methoxsalen [PDF]
Thesis (M.Sc.(Pharmacology))--North-West University, Potchefstroom Campus, 2004.Cyclosporine forms the cornerstone of therapy to prevent rejection after organ transplantation.
Bouwer, Máralien
core
EDA Complex‐Driven Desaturation of Heterocyclic Carbonyl Compounds Enabled by HFIP
In this work, we report a novel light‐mediated desaturation strategy enabled by electron donor–acceptor complex formation. DFT and mechanistic studies reveal that the reaction proceeds via single‐electron transfer, hydrogen atom transfer, and base‐mediated deprotonation sequentially with pyridinium salt serving dually as oxidant and base, and ...
Rakesh Maiti +6 more
wiley +2 more sources
Methoxsalen with ultraviolet A therapy.
A cohort study of 1,380 psoriasis patients treated with PUVA found that the risk of skin cancer (squamous-cell carcinoma) increased with increasing exposure to PUVA; exposure to high doses of PUVA increased the risk of cancer by more than 50-fold.
semanticscholar +1 more source
Electrochemical Three‐Component Synthesis of Heteroaryl Sulfonates
An electrochemical, metal‐free three‐component strategy for direct C(sp2)─H sulfonation of electron‐rich heteroarenes using SO2 and alcohols is described. Utilizing inexpensive graphite electrodes and practical SO2 stock solutions under mild conditions, this method provides straightforward access to heteroaryl sulfonates from simple building blocks ...
Po‐Chung Chien +2 more
wiley +1 more source
Cinnamon (Cinnamomum spp.) is used as a culinary spice and dietary supplement. A major constituent, cinnamaldehyde, was previously shown to inactivate cytochrome P450 (CYP) 2A6 in vitro. A mechanistic static model predicted an ~5‐fold increase in the AUC of the CYP2A6 substrates nicotine and letrozole.
Aiden‐Hung P. Nguyen +8 more
wiley +1 more source
The time course of topical PUVA erythema following 15- and 5-minute methoxsalen immersion
Limited data exist in the literature concerning the characteristics of erythema following psoralen UV-A (PUVA) treatment using topical methoxsalen. To optimize the phototherapeutic regimen and reduce short- and long-term risks, knowledge of such basic ...
Ibbotson, Sally H. +4 more
core +1 more source

