Results 31 to 40 of about 2,064 (176)

Angelica keiskei, an emerging medicinal herb with various bioactive constituents and biological activities. [PDF]

, 2017
Angelica keiskei (Miq.) Koidz. (Umbelliferae) has traditionally been used to treat dysuria, dyschezia, and dysgalactia as well as to restore vitality. Recently, the aerial parts of A. keiskei have been consumed as a health food.
Jafari, Mahtab, Kil, Yun-Seo, Pham, Sally T, Seo, Eun Kyoung   +3 more
core   +1 more source

A Perspective on the Use of NB-UVB Phototherapy vs. PUVA Photochemotherapy [PDF]

, 2018
Narrowband UVB (NB-UVB) phototherapy and psoralen-UVA (PUVA) photochemotherapy are widely used phototherapeutic modalities for a range of skin diseases.
Ahmad, Archier, Archier, Aslam, Atzmony, Aydogan, Behrens-Williams, Berroeta, Bhatnagar, Bhatnagar, Bilsland, Bilsland, Bishnoi, Boswell, Brazzelli, Bruynzeel, Calzavara-Pinton, Calzavara-Pinton, Cameron, Cameron, Carter, Chalmers, Chauhan, Chen, Clayton, Collins, Cunningham, Dawe, Dawe, Dawe, Dawe, De, Decock, Der-Petrossian, Diederen, El-Mofty, Engin, Farnaghi, Fernandez-Guarino, Foerster, Garritsen, George, Godt, Gordon, Grandi, Green, Grundmann-Kollmann, Halpern, Harrop, Healy, Hearn, Hindson, Hindson, Hofer, Holme, Hoot, Hudson-Peacock, Ibbotson, Ibbotson, Iraji, Karvonen, Kerscher, Khafagy, Knobler, Kolde, Larko, Lever, Lindelof, Ling, Man, Man, Man, Man, Markham, Mastalier, Mckenna, Menage, Messenger, Millington, Mobacken, Mohamed, Morgado-Carrasco, Murray, Norris, Olsen, Parrish, Pavlovsky, Radakovic, Robinson, Roelandts, Roelandts, Ros, Rosen, Rosen, Rosen, Salem, Sapam, Sevrain, Sezer, Sivaramakrishnan, Snellman, Solak, Stern, Stern, Stern, Stern, Stern, Stern, Tanew, Tanew, Taylor, Tegner, Tzaneva, Van, Van, Wackernagel, Warren, Westerhof, Yones, Yones   +119 more
core   +3 more sources

The Novel CYP2A6 Inhibitor, DLCI-1, Decreases Nicotine Self-Administration in Mice. [PDF]

, 2020
During tobacco and e-cigarette use, nicotine is mainly metabolized in the human liver by cytochrome P450 2A6 (CYP2A6). Given that a slower CYP2A6 metabolism has been associated with less vulnerability to develop nicotine dependence, the current studies ...
Chen, Yen-Chu, Denton, Travis T, Fowler, Christie D, Fowler, James P, Lazarus, Philip, Sherafat, Yasmine, Staben, Andres, Wang, Jing, Watson, Christy JW   +8 more
core  

The Dark Side of the Light: Phototherapy Adverse Effects [PDF]

, 2016
Phototherapy is a valuable therapeutic tool in Dermatology, but there may be drawbacks. Acute and long-term adverse effects, of variable severity, include skin erythema, xerosis, pruritus, blistering, altered pigmentation, photoaging, and ...
Apetato, M, Valejo Coelho, M
core   +1 more source

Dynamic Rearrangement of Cell States Detected by Systematic Screening of Sequential Anticancer Treatments [PDF]

, 2017
Signaling networks are nonlinear and complex, involving a large ensemble of dynamic interaction states that fluctuate in space and time. However, therapeutic strategies, such as combination chemotherapy, rarely consider the timing of drug perturbations ...
Blicher Bjerregård, Mathias, Cox, Thomas R., Erler, Janine T., Ferkinghoff-Borg, Jesper, Koplev, Simon, Linding, Rune, Longden, James, Pedersen, Jesper T., Sommer, Morten Otto Alexander, Voellmy, Franziska   +9 more
core   +3 more sources

Studies on Regioselective Binding Mode of Steroid Molecules in Homology Modeled Cytochrome P450-2C11 [PDF]

, 2009
In this study, we investigated the regioselective binding mode of steroid molecules and structure requirements for steroid molecules for 16[alpha]-hydroxylation by Cytochrome P450-2C11.
Eiichi Akaho, Hamed I. Ali, Hukihisa Fujita, Morio Yamada   +3 more
core   +1 more source

Novel benzopsoralen analogues : synthesis, biological activity and molecular docking studies [PDF]

, 2014
New benzopsoralen analogues were synthesized and their inhibitory effect on the growth of tumourtumour cell lines (MDA MB231 and TCC-SUP) was evaluated.
Campos, Ana M. F. Oliveira, Cerqueira, N. M. F. S. A., Esteves, Ana Paula, Francisco, Carla Santana, Rodrigues, L. R.   +4 more
core   +1 more source

Introducing the Cis‐2,3‐Bis(trifluoromethyl)cyclopropyl Chemotype: Late‐Stage Installation and Stereoelectronic Properties

ChemistryEurope, Volume 4, Issue 2, February 2026.
The cis‐2,3‐bis(trifluoromethyl)cyclopropyl chemotype is introduced. The steric demand of this motif is intermediate between that of the heptafluoroisopropyl and prefluorotertbutyl groups; yet, it induces significantly less lipophilicity than these due to its facial polarity.
Daniel Gaviña, Zeyu Feng, David Herrero, Martin Simon, Christopher Golz, Manuel Alcarazo   +5 more
wiley   +1 more source

Randomized controlled study of ECP with methoxsalen as first-line treatment of patients with moderate to severe cGVHD

Blood Advances, 2019
: The investigation of extracorporeal photopheresis (ECP) plus standard of care (SoC) (SoC+ECP) in chronic graft-versus-host disease (cGVHD) within prospective, randomized clinical studies is limited, despite its frequent clinical use. This phase 1/pilot
Madan Jagasia, Christof Scheid, Gérard Socié, Francis Ayuketang Ayuk, Johanna Tischer, Michele L. Donato, Árpád Bátai, Heidi Chen, Sheau-Chiann Chen, Thomas Chin, Henri Boodée, Ghaith Mitri, Hildegard T. Greinix   +12 more
doaj   +1 more source

Synthesis of novel benzofurocoumarin analogues and their anti-proliferative effect on human cancer cell lines [PDF]

, 2012
The synthesis of five new tetracyclic benzofurocoumarin (benzopsoralen) analogues is described. Their inhibitory effects on the growth of three human tumour cell lines (MDA MB 231 (breast adenocarcinoma), HeLa (cervix adenocarcinoma) and TCC-SUP (bladder
Campos, Ana M. F. Oliveira, Cerqueira, N. M. F. S. A., Francisco, Carla S., Rodrigues, L. R., Rodrigues, Lígia M.   +4 more
core   +1 more source