Results 11 to 20 of about 1,011 (137)

<i>Pastinaca sativa</i> L.: Nutritional Composition, Phytochemistry, and Pharmacological Properties Supporting Its Potential as a Functional Food and Therapeutic Agent. [PDF]

Food Sci Nutr
Food‐grade processing of Pastinaca sativa (parsnip) converts a nutrient‐rich plant matrix (dietary fiber, fructans, phenolics) through washing/slicing/enzymatic treatment and ingredient preparation into functional food ingredients, including fiber concentrates, antioxidant‐rich fractions, and parsnip powders/extracts.
Khatua S, Nag A, Sen S, Sarkar J, Acharya K, Calina D, Setzer WN, Sharifi-Rad J.   +7 more
europepmc   +2 more sources

Dehydrocostus Lactone Inhibits Microglia-Mediated Neuroinflammation by Targeting CYP2A6 to Improve Ischemic Brain Injury. [PDF]

CNS Neurosci Ther
Dehydrocostus lactone (DHC) inhibits microglia‐mediated neuroinflammation by targeting CYP2A6, reducing the release of pro‐inflammatory factors and improving nerve function impairment, thereby alleviating ischemic brain injury. ABSTRACT Background Neuroinflammation is an important factor in ischemic stroke.
Shu X, Zou X, Zhang J, Fang X, Wang X, Wu H, He X, Sha D.   +7 more
europepmc   +2 more sources

Protective Effects of Methoxsalen Supplementation on Chronic Alcohol-induced Osteopenia and Steatosis in Rats

Molecules, 2020
Osteopenia or osteoporosis occurs frequently in alcoholics and patients with alcoholic fatty liver disease. Methoxsalen (MTS), 8-methoxypsoralen, improved osteoporosis in ovariectomized and diabetic mouse models; however, its effects on alcohol-induced ...
Ju Ri Ham, Ra-Yeong Choi, Hae-In Lee, Mi-Kyung Lee   +3 more
doaj   +1 more source

Suppressive CD8+ T-Cells Are Key Cellular Mediators of Extracorporeal Photopheresis. [PDF]

J Clin Apher
ABSTRACT Extracorporeal photopheresis (ECP) is a widely utilized immunomodulatory procedure with an incompletely defined mechanism. In graft‐versus‐host disease (GvHD) and transplant rejection, ECP is thought to induce immune tolerance by increasing regulatory CD4+ T‐cells, whereas in cutaneous T cell lymphoa it may enhance dendritic cell–mediated ...
Rogers KJ, Eschbacher KL, Zacharias Z, Kale K, Crawford MP, Knudson CM, Boyden AW, Karandikar NJ.   +7 more
europepmc   +2 more sources

PROMISING SCAFFOLD AND TREATMENT FOR ULCERATIVE COLITIS: ISOLATION, IN VIVO AND IN SILICO STUDIES [PDF]

Egyptian Journal of Desert Research
Methoxsalen compound was isolated from Ammi majus seeds in very good amount, purity (almost 90%) and few steps method which don’t include column chromatography (extraction by ethanol, extraction by dichloromethane, crystallization by methanol (60%) and ...
Ahmed Selim
doaj   +1 more source

Stability-indicating RP-HPLC method for simultaneous determination of methoxsalen and p-aminobenzoic acid in binary combination

Bulletin of the Chemical Society of Ethiopia, 2015
An accurate, simple and specific reverse phase LC procedure is established and validated for simultaneous estimation of methoxsalen and p-aminobenzoic acid in pharmaceutical formulated products and human serum.
P. John, W. Azeem, M. Ashfaq, I. U. Khan, S. N. Razzaq, S. Ud-Din Khan   +5 more
doaj   +1 more source

New Chitosan Polymer Scaffold Schiff Bases as Potential Cytotoxic Activity: Synthesis, Molecular Docking, and Physiochemical Characterization

Frontiers in Chemistry, 2022
In this work, we synthesize the sulfonated Schiff bases of the chitosan derivatives 2a-2j without the use of a catalyst in two moderately straightforward steps with good yield within a short reaction time.
Ponnusamy Packialakshmi, Perumal Gobinath, Daoud Ali, Saud Alarifi, Raman Gurusamy, Akbar Idhayadhulla, Radhakrishnan Surendrakumar   +6 more
doaj   +1 more source

EDA Complex-Driven Desaturation of Heterocyclic Carbonyl Compounds Enabled by HFIP. [PDF]

Angew Chem Int Ed Engl
In this work, we report a novel light‐mediated desaturation strategy enabled by electron donor–acceptor complex formation. DFT and mechanistic studies reveal that the reaction proceeds via single‐electron transfer, hydrogen atom transfer, and base‐mediated deprotonation sequentially with pyridinium salt serving dually as oxidant and base, and ...
Maiti R, Cauwenbergh R, Nath A, Guimarães ABR, Qin Y, Maseras F, Das S.   +6 more
europepmc   +3 more sources

A Study of the Furocoumarin Derivative of Ruta Chalepensis L. (Rutaceae)

Iraqi Journal of Pharmaceutical Sciences, 2017
The content of Furocoumarin derivatives (Psoralens) of Ruta Chalepensis L. (Whole plant) was studied by simple extraction with petroleum ether (b.p. 60-80Co).
Ekbal H.AL-Khateeb, Ali A. AL-Shamma, Bajes A. Nehar   +2 more
doaj   +3 more sources

Methoxsalen-induced macular toxicity

Indian Journal of Ophthalmology, 2017
Psoralen compounds such as methoxsalen are photosensitizer agents used in conjunction with ultraviolet A (UVA) radiation exposure as photochemotherapy (Psoralens and ultraviolet-A therapy [PUVA therapy]) for certain epidermal skin disorders such as ...
Aditya Maitray, Pukhraj Rishi
doaj   +1 more source