Results 91 to 100 of about 795,435 (189)
The World Journal of Men's HealthPurpose: The mesoderm specific transcription (MEST) gene is a paternally expressed imprinted gene that appears to play a role in embryo survival. The latest meta-analysis on MEST methylation pattern in spermatozoa of infertile patients found higher ...
Rossella Cannarella +6 more
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EpigeneticsThymic Stromal Lymphopoietin (TSLP), an immunomodulatory cytokine, plays a pivotal role in the development and progression of atopic and allergic diseases.
Krishna Priya Ganti, Milan Surjit
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Frontiers in ImmunologyBackgroundGlioma is one of the most common tumors, characterized by a high incidence rate and mortality, posing a formidable global health challenge. Palmitoylation represents a significant post-translational modification that holds a pivotal role in the
Jihao Xue +9 more
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Histone methylation and acetylation in cancer: mechanism, progression, and targets
OncologieAlong with the continuous development of chromatin immunoprecipitation sequencing and its derivative technologies, as well as an increased understanding of epigenetic modification, the post-translational modification of histones has gradually been ...
Bu Su +4 more
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Frontiers in OncologyIntroduction3 - Mercaptopyruvate Sulfurtransferase (3 - MST) is an enzyme encoded by the Mercaptopyruvate Sulfurtransferase (MPST) gene. The enzyme is associated with a variety of cancers such as lung adenocarcinoma.
Boran Cui +10 more
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METTL3‐m6A‐SLC25A11 Axis Promotes Chronic Hypoxia–Induced Cardiomyocyte Ferroptosis
Journal of the American Heart Association: Cardiovascular and Cerebrovascular DiseaseBackground Chronic hypoxia is commonly associated with various cardiovascular diseases, with cardiomyocyte death being the most frequently observed alteration. Mitochondrial dysfunction is another consequence seen in the hypoxic heart.
Yansong Li +5 more
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Diagnostic value of multi-gene methylation in colorectal cancer screening
Frontiers in OncologyObjectiveTo evaluate the diagnostic value and clinical application of multi-gene methylation assay in colorectal cancer (CRC) screening.MethodsThis was a single-center, retrospective, real-world study conducted at the First Affiliated Hospital of Shantou
Qingyan Yang, Qingyan Yang, Liming Chen
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Demethylation of leptin promoter in gestational diabetes mellitus: evidence from a mouse model
Frontiers in Cell and Developmental BiologyBackgroundGestational diabetes mellitus (GDM) has been linked to altered leptin (LEP) gene methylation, which may disrupt maternal glucose metabolism and the associated placental signaling.
Linlin Hu +12 more
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