Results 81 to 90 of about 795,435 (189)

Implications of petrochemical exposure and epigenetic alterations on human health

Frontiers in Toxicology
The petrochemical industry and automobiles contribute significantly to hazardous waste, which contains a broad array of organic and inorganic compounds posing serious health risks.
Selvaraj Jayaraman, Anupriya Eswaran, Vishnu Priya Veeraraghavan, Mohammed Fazal, Adham Al-Rahbi, Srinivasa Rao Sirasanagandla   +5 more
doaj   +1 more source

Maternal adverse childhood experiences (ACEs) and offspring imprinted gene DMR methylation at birth

Epigenetics
Adverse childhood experiences (ACEs) contribute to numerous negative health outcomes across the life course and across generations. Here, we extend prior work by examining the association of maternal ACEs, and their interaction with financial stress and ...
Adriana C. Vidal, David W. Sosnowski, Joddy Marchesoni, Carole Grenier, John Thorp, Susan K. Murphy, Sara B. Johnson, William Schlief, Cathrine Hoyo   +8 more
doaj   +1 more source

Epigenetics of suicidal behavior

Вавиловский журнал генетики и селекции, 2019
Suicide is the second leading cause of death among young people and therefore being a serious global problem worldwide. The study of genetic and epigenetic factors in the development of suicidal behavior plays an important role in the development of ...
R. N. Mustafin, A. V. Kazantseva, R. F. Enikeeva, Yu. D. Davydova, S. B. Malykh, V. V. Viktorov, E. K. Khusnutdinova   +6 more
doaj   +1 more source

Decoding epigenetic markers: implications of traits and genes through DNA methylation in resilience and susceptibility to mastitis in dairy cows

Epigenetics
Cattle farming faces challenges linked to intensive exploitation and climate change, requiring the reinforcement of animal resilience in response to these dynamic environments.
Lotfi Bouzeraa, Helene Martin, Clement Plessis, Pascal Dufour, Jessica C. S. Marques, Sydney Moore, Ronaldo Cerri, Marc-Andre Sirard   +7 more
doaj   +1 more source

Magic methylation with methyl-containing peroxides

Chemical Science
Methyl groups are abundant in pharmaceuticals, and their installation has garnered significant attention. This review summarises advancements in the use of methyl-containing peroxides as reagents for a variety of methylation reactions.
Daliah Farajat, Yuhua Zhang, Chao-Jun Li
openaire   +2 more sources

Prediction of NR3C1 as a methylation marker for the prevention and treatment of gastric cancer in Rhizoma Atractylodis Macrocephalae based on machine learning algorithm and bioinformatics analysis

Frontiers in Genetics
ObjectiveThe aim of this study was to identify the markers of Rhizoma Atractylodis Macrocephalae (RAM) for the prevention and treatment of gastric cancer using bioinformatics analysis.MethodsThe main active components of RAM were screened using the ...
Shicong Huang, Qian Gu, Yan Chen, Xiaofang Huang, Yuhua Du, Ziying Zhou, Yi Nan, Ling Yuan   +7 more
doaj   +1 more source

Correlation between MGMT methylation and the efficacy of bevacizumab in high-grade glioma

Frontiers in Oncology
PurposeThe aim of this study is to investigate whether the therapeutic efficacy of bevacizumab (BEV) in the treatment of high-grade glioma (HGG) is associated with the methylation status of O6-methylguanine-DNA methyltransferase (MGMT) on the basis of ...
Chengrui Yan, Xuexue Bai, Chao Wu, Wenbin Ma, Ming Feng   +4 more
doaj   +1 more source

Multidimensional roles of cfDNA fragmentomics in preeclampsia: from placental hypoxia and TLR9 inflammation to clinical risk stratification

Frontiers in Medicine
Cell-free DNA (cfDNA) has emerged as a pivotal biomarker for predicting preeclampsia (PE), a multisystem syndrome characterized by placental hypoperfusion and systemic inflammation.
Ziyi Guo, Bin Zhang, Di Yang, Li Wang
doaj   +1 more source

The biological embedding of early-life socioeconomic status and family adversity in children's genome-wide DNA methylation. [PDF]

, 2018
AimTo examine variation in child DNA methylation to assess its potential as a pathway for effects of childhood social adversity on health across the life course.Materials & methodsIn a diverse, prospective community sample of 178 kindergarten ...
Adler, Nancy E, Boyce, W Thomas, Bush, Nicole R, Edgar, Rachel D, Essex, Marilyn J, Kobor, Michael S, MacIsaac, Julia L, McEwen, Lisa M, Park, Mina   +8 more
core   +1 more source

Functional Implications of DNA Methylation in Adipose Biology. [PDF]

, 2019
The twin epidemics of obesity and type 2 diabetes (T2D) are a serious health, social, and economic issue. The dysregulation of adipose tissue biology is central to the development of these two metabolic disorders, as adipose tissue plays a pivotal role ...
Kang, Sona, Ma, Xiang
core