Results 111 to 120 of about 443,290 (339)

H(O)TA: estimation of DNA methylation and hydroxylation levels and efficiencies from time course data [PDF]

arXiv, 2016
Methylation and hydroxylation of cytosines to form 5-methylcytosine (5mC) and 5-droxymethylcytosine (5hmC) belong to the most important epigenetic modifications and their vital role in the regulation of gene expression has been widely recognized. Recent experimental techniques allow to infer methylation and hydroxylation levels at CpG dinucleotides but
arxiv  

On the Biological Methylation of Histamine. 4. [PDF]

, 1959
Kerstin M. Lindahl, Artturi I. Virtanen, Sigvard Eriksson, C.-G. Hedén, B. Malmgren, H. Palmstierna   +5 more
openalex   +1 more source

Functional Biomaterials Derived from Protein Liquid–Liquid Phase Separation and Liquid‐to‐Solid Transition

Advanced Materials, EarlyView.
Protein can undergo liquid–liquid phase separation and liquid‐to‐solid transition to form liquid condensates and solid aggregates. These phase transitions can be influenced by post‐translational modifications, mutations, and various environmental factors.
Tianchen Li, Dea Ilhamsyah, Benedict Tai, Yi Shen   +3 more
wiley   +1 more source

Adjusting Cell‐Surface Interactions Through a Covalent Immobilization of Biomolecules

Advanced Materials Interfaces, EarlyView.
This review presents an overview of current and emerging immobilization techniques coupled with an in‐depth investigation of the underlying mechanisms governing the activity and stability of covalently immobilized biomolecules. The aim of this study is to serve as a guide for the development of long‐lasting biomedical coatings with versatile biological
Sara Shakibania, Manus J. P. Biggs, Katarzyna Krukiewicz   +2 more
wiley   +1 more source

Methylation Operation Wizard (MeOW): Identification of differentially methylated regions in long-read sequencing data [PDF]

arXiv
Long-read sequencing (LRS) is able to simultaneously capture information about both DNA sequence and modifications, such as CpG methylation in a single sequencing experiment. Here we present Methylation Operation Wizard (MeOW), a program to identify and prioritize differentially methylated regions (DMRs) genome-wide using LRS data.
arxiv  

Current Advances of Antibacterial Biomaterials for Bone Regeneration

Advanced Materials Interfaces, EarlyView.
Effective treatment of infectious bone defects requires not only robust bone regeneration, but also the elimination of bacterial infection. This review highlights current cutting‐edge concepts and innovations in synthetic bone repair biomaterials and antibacterial bone repair materials, aiming to promote clinical translation and inspire broader ...
Xueping Kong, Xue Zhang, Ying Wang, Ben Zhang   +3 more
wiley   +1 more source

Mathematical framework of epigenetic DNA methylation in gene body Arabidopsis [PDF]

arXiv, 2012
In aiming to explain the establishment, maintenance and stability of methylation pattern in gene body of Arabidopsis we propose here a theoretical framework for understanding how the methylated and unmethylated states of cytosine residues are maintained and transmitted during DNA replication.
arxiv  

Frequency‐Dependent Demethylation of Cancer DNAs by High‐Power Terahertz Radiation

Advanced Photonics Research, EarlyView.
Effective demethylation of cancer DNA is successfully demonstrated by resonant irradiation with high‐power terahertz (THz) waves at the 10 mW level, combined with metamaterial‐based THz filters. The dependence of spectral filtering on demethylation indicates that the resonant frequency of 1.6 THz of cancer DNAs plays a crucial role in reducing the ...
Chaeyoon Kim, Seung Won Jin, Seong Cheol Lee, Donghak Oh, Soojeong Baek, Bumki Min, Hee‐Jin Yang, Joo‐Hiuk Son, Fabian Rotermund   +8 more
wiley   +1 more source

DMRIntTk: integrating different DMR sets based on density peak clustering [PDF]

arXiv
\textbf{Background}: Identifying differentially methylated regions (DMRs) is a basic task in DNA methylation analysis. However, due to the different strategies adopted, different DMR sets will be predicted on the same dataset, which poses a challenge in selecting a reliable and comprehensive DMR set for downstream analysis.
arxiv  

Dual Charge Transfer Mechanisms in Intimately Bonded S‐scheme Heterojunction Photocatalyst with Expeditious Activity toward Environmental Remediation

Advanced Sustainable Systems, EarlyView.
A novel MBOdCN S‐scheme heterojunction photocatalyst is fabricated using pristine Mg‐Bi2O3 and grayish g‐C3N4, where dynamic dual charge migration paths occur to accelerate exciton dissociation. This composite catalyst realizes high degradation efficiency of up to 99.56% of oxytetracycline (OTC) removal under optimized conditions. The material exhibits
Potlako J. Mafa, Mope E. Malefane, Francis Opoku, Adewale O. Oladipo, Gcina Mamba, Tunde L. Yusuf, Jemal Fito Nure, Sogolo L. Lebelo, Dan Liu, Jianzhou Gui, Bhekie B. Mamba, Alex T. Kuvarega   +11 more
wiley   +1 more source