Results 181 to 190 of about 652,669 (356)

The ISW1 and CHD1 chromatin remodelers suppress global nucleosome dynamics in living yeast cells. [PDF]

Sci Adv
Xu Z, Prajapati HK, Eriksson PR, Clark DJ.   +3 more
europepmc   +1 more source

Small RNA Toxin‐Assisted Evolution of GC‐Preferred ErCas12a for Enhanced Genome Targeting Range

Advanced Science, EarlyView.
ErCas12a is engineered to target GC‐rich PAMs using a small RNA toxin‐aided positive screening system. The resulting variant, enErCas12a, exhibits an expanded PAM profile and facilitates efficient gene editing in both bacterial and mammalian cells, while preserving high targeting specificity for both canonical and non‐canonical PAM targets.
Zehua Chen, Junyuan Xue, Ziying Wang, Jinyuan Sun, Yinglu Cui, Tong Zhu, Huaiyi Yang, Ming Li, Bian Wu   +8 more
wiley   +1 more source

ctDNA methylation profiling reveals NBL1 as a promising biomarker for early ovarian cancer screening. [PDF]

World J Surg Oncol
Zhou S, Yin H, Yan L, Xie N, Fu C.
europepmc   +1 more source

The Methylation of 3, 4-Dihydro-2H-1, 3-benzoxazine-2-thione-4-one

, 1968
宮崎 幸信, 小坂 琿吾, 上村 英雄   +2 more
openalex   +2 more sources

METHYLATION OF SUGAR DITHIOACETALS: III. D-GALACTOSE DIETHYL DITHIOACETAL [PDF]

, 1962
Guy G.S. Dutton, Yoshie Tanaka
openalex   +1 more source

THE METHYL ESTER OF METHYLATED HYALURONIC ACID

Journal of Biological Chemistry, 1952
openaire   +3 more sources

Restoration of SIRT3 Expression in Aged Mice Alleviates UUO‐Induced Renal Fibrosis by Reducing GSK‐3β Hyperacetylation

Advanced Science, EarlyView.
SIRT3 expression is significantly downregulated in the aged kidney, rendering the kidney more vulnerable to fibrotic changes in obstructive nephropathy. By promoting GSK‐3β deacetylation, SIRT3 indirectly inhibits Wnt/β‐catenin signaling, thereby suppressing renal fibrosis.
Jing Wang, Xiang Ren, Huan Lu, Zihao Guo, Xing Li, Yiqun Tian, Yisheng Yin, Zhenliang Qin, Kun Yun, Minglong Wu, Gang Chen, Xiaoyong Zeng   +11 more
wiley   +1 more source

Long interspersed nuclear element 1 methylation in non-small cell lung cancer: implications for diagnosis, prognosis, and therapeutic targeting. [PDF]

Cell Commun Signal
Arachchillage DPW, Udomsinprasert W.
europepmc   +1 more source

Partial Methylation of Dextran. [PDF]

, 1968
B. Norrman, I. Wadsö, Pertti Karvonen, Artturi I. Virtanen, Jaakko Paasiv́irta   +4 more
openalex   +1 more source

Comparative Analysis of Clinical Outcomes and Financial Aspects of Phototherapies and Immunotherapy for Cancer

Advanced Science, EarlyView.
This review compares clinical outcomes, translational progress, and global funding trends across cancer phototherapies—photodynamic, photothermal, and photoimmunotherapy—and conventional immunotherapy. It highlights differences in treatment efficacy, clinical trial status, financial investment, and regulatory challenges, providing a comprehensive ...
Deepak S. Chauhan, Kun Shao, Roopa Hebbandi Nanjundappa, Daniel‐Jiajun Yu, Marianne Stanford, Huile Gao, Channakeshava Sokke Umeshappa   +6 more
wiley   +1 more source