Advanced Science, EarlyView.This study investigates the integrated diagnostic and therapeutic strategy utilizing 89Zr/131I‐labeled tinurilimab for the management of malignant lung nodules, with a particular focus on lung adenocarcinoma (LUAD). CEACAM6, which is highly expressed in most LUAD patients, activates the Src/FAK signaling pathway, thereby promoting cell proliferation ...
Chongyang Chen +8 more
wiley +1 more source
Association of Intergenic and Intragenic <i>MGMT</i> Enhancer Methylation with <i>MGMT</i> Promoter Methylation, MGMT Protein Expression and Clinical and Demographic Parameters in Glioblastoma. [PDF]
Int J Mol SciPühringer K +6 more
europepmc +1 more source
Partial Methylation Studies on Pustulan, Methyl alpha- and beta-D-Glucopyranoside, and Some Derivatives. [PDF]
, 1968 B. Norrman +4 more
openalex +1 more source
RACK7 Interacts with PRC2 Complex to Regulate Astrocyte Development
Advanced Science, EarlyView.The study investigates the role of RACK7 in brain development using a conditional knockout mouse model. RACK7 deficiency results in developmental defects and abnormal astrocyte development by disrupting H3K27me3 chromatin binding. The underlying mechanism involves RACK7 interacting with the PRC2 complex to regulate the genomic localization of SUZ12 and
Fangfang Jiao +9 more
wiley +1 more source
Effects of Ionizing Radiation on DNA Methylation Patterns and Their Potential as Biomarkers. [PDF]
Int J Mol SciMa L +6 more
europepmc +1 more source
Studies on the Enzymic Methylation of Histamine. [PDF]
, 1964 Arne Gustafsson +3 more
openalex +1 more source
Advanced Science, EarlyView.Cardiomyocyte‐enriched USP20 regulates the K63‐linked ubiquitination of STAT3, and the cardiomyocyte‐specific USP20‐STAT3‐CARM1 axis exerts a protective role in cardiac hypertrophy. Targeting USP20 through cardiac‐specific gene therapy presents a promising strategy for the treatment of cardiac hypertrophy.
Lingfeng Zhong +15 more
wiley +1 more source
Acetaldehyde-driven mRNA methylation and expression changes in ethanol-metabolizing enzyme genes. [PDF]
EpigeneticsKoo JS, Zhan Q, Zhang H.
europepmc +1 more source
THE METHYL ESTER OF METHYLATED HYALURONIC ACID
Journal of Biological Chemistry, 1952 openaire +3 more sources
The Methylation of 3, 4-Dihydro-2H-1, 3-benzoxazine-2-thione-4-one
, 1968 宮崎 幸信 +2 more
openalex +2 more sources