Methyl 2-methyl-3,5-dinitrobenzoate [PDF]
In the title compound, C(9)H(8)N(2)O(6), the methyl ester group is almost planar (r.m.s. deviation = 0.002 Å) and is oriented at a dihedral angle of 24.27 (16) ° with respect to the benzene ring. The nitro groups make dihedral angles of 4.2 (5) ° and 60.21 (11) ° with the benzene ring.
Rizwan Raza +4 more
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Synthesis of (.+-.)-methyl epijasmonate and (.+-.)-methyl cucurbate. [PDF]
A novel synthesis of ( ± )-methyl epijasomonate (2) and the first synthesis of ( ± )-methyl cucurbate (4) were achieved starting from 2-allylcyclohexane-1,3-dione (8). The synthetic epimer 2 had a stronger jasmin flavor than the trans-isomer 1 with 95% purity.
KITAHARA, Takeshi +4 more
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The structure of the title compound, C(9)H(10)O(2), is related to that of 4-methyl-phenyl 4-methyl-benzoate and ethyl-ene di-4-methyl-benzoate showing similar bond parameters. The mol-ecule is planar, the dihedral angle between the aromatic ring and the -COOMe group being 0.95 (6)°. The cystal structure exhibits inter-molecular C-H⋯O contacts that link
Ulrich Flörke +2 more
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Maternal nutritional status, C1 metabolism and offspring DNA methylation: a review of current evidence in human subjects. [PDF]
: Evidence is growing for the long-term effects of environmental factors during early-life on later disease susceptibility. It is believed that epigenetic mechanisms (changes in gene function not mediated by DNA sequence alteration), particularly DNA ...
Dominguez Salas, Paula +19 more
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In Vivo Control of CpG and Non-CpG DNA Methylation by DNA Methyltransferases [PDF]
The enzymatic control of the setting and maintenance of symmetric and non-symmetric DNA methylation patterns in a particular genome context is not well understood.
Julia Arand (155279) +55 more
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From trans-methylation to cytosine methylation: Evolution of the methylation hypothesis of schizophrenia [PDF]
The role of methylation in the history of psychiatry has traversed a storied path. The original trans-methylation hypothesis was proposed at a time when chlorpromazine had been synthesized but not yet marketed as an antipsychotic (Thorazine).
Dennis R, Grayson +4 more
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VEZF1 elements mediate protection from DNA methylation [PDF]
There is growing consensus that genome organization and long-range gene regulation involves partitioning of the genome into domains of distinct epigenetic chromatin states.
Gowher Humaira +21 more
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Absolute quantitation of DNA methylation of 28 candidate genes in prostate cancer using pyrosequencing [PDF]
This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.Aberrant DNA methylation plays a pivotal
Vasiljevic, N +14 more
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The Dnmt3L ADD Domain Controls Cytosine Methylation Establishment during Spermatogenesis [PDF]
A critical aspect of mammalian gametogenesis is the reprogramming of genomic DNA methylation. The catalytically inactive adaptor Dnmt3L is essential to ensuring this occurs correctly, but the mechanism by which it functions is unclear.
Robert J. Schmitz +32 more
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Epigenetic regulation during fetal femur development: DNA methylation matters [PDF]
Epigenetic modifications are heritable changes in gene expression without changes in DNA sequence. DNA methylation has been implicated in the control of several cellular processes including differentiation, gene regulation, development, genomic ...
Oreffo Richard O. C. +34 more
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