Differential methylation pattern in pubertal girls associated with biochemical premature adrenarche
Epigenetics, 2023 Biochemical premature adrenarche is defined by elevated serum DHEAS [≥40 μg/dL] before age 8 y in girls. This condition is receiving more attention due to its association with obesity, hyperinsulinemia, dyslipidemia, and polycystic ovary syndrome ...
Diana Ponce +9 more
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Epigenetic marks as the link between environment and development: examination of the associations between attachment, socioeconomic status, and methylation of the SLC6A4 gene. [PDF]
, 2016 BackgroundEpigenetic processes act as a link between environment and individual development. This pilot study examined the association between socioeconomic status (SES), attachment, and methylation of the promoter region of the serotonin transporter ...
Allen, Isabel Elaine +3 more
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Epigenomics, 2012 A striking feature of mammalian genomes is the paucity of the CG dinucleotide. There are approximately 20,000 regions termed CpG islands where CGs cluster. This represents 5% of all CGs and 1% of the genome. CpG islands are typically unmethylated and are often promoters for housekeeping genes.
Charles, Vinson, Raghunath, Chatterjee
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Epigenetics, 2022 Physical activity reduces risk of colon cancer by 20–30%. Aberrant methylation patterns are common epigenetic alterations in colorectal adenomas, and cancers and play a role in cancer initiation and progression.
Catherine Duggan +6 more
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SUVH1, a Su(var)3-9 family member, promotes the expression of genes targeted by DNA methylation. [PDF]
, 2015 Transposable elements are found throughout the genomes of all organisms. Repressive marks such as DNA methylation and histone H3 lysine 9 (H3K9) methylation silence these elements and maintain genome integrity.
Chen, Xuemei +6 more
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Plants regenerated from tissue culture contain stable epigenome changes in rice. [PDF]
, 2013 Most transgenic crops are produced through tissue culture. The impact of utilizing such methods on the plant epigenome is poorly understood. Here we generated whole-genome, single-nucleotide resolution maps of DNA methylation in several regenerated rice ...
Bellizzi, Maria +8 more
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Assessing the preservation of cytosine methylation in ancient DNA from five prehistoric Native American populations [PDF]
, 2015 textCytosine methylation of CpG dinucleotides is an important epigenetic mark that regulates gene expression in humans. While methylation patterns in extant populations have been widely studied, few studies have attempted to analyze methylation in ...
Smith, Ricky Wayne Aldon
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Advanced Science, 2023 Dental pulp stem cells (DPSCs), characterized by easy availability, multi‐lineage differentiation ability, and high proliferation ability, are ideal seed cells for cartilage tissue engineering.
Qiannan Sun +7 more
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Modeling DNA methylation dynamics with approaches from phylogenetics [PDF]
, 2014 Methylation of CpG dinucleotides is a prevalent epigenetic modification that is required for proper development in vertebrates, and changes in CpG methylation are essential to cellular differentiation.
Capra, John A., Kostka, Dennis
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Analysis of SDC2 and SEPT9 promoters methylation in plasma cfDNA to detect colorectal and precancerous lesions [PDF]
Exploration of MedicineAim: Analysis of circulating free DNA (cfDNA) is now broadly used to diagnose, assess treatment response, and recurrence of various tumor types. Detection of aberrant cfDNA methylation in plasma is considered as one of the promising approaches for early ...
Viktoria Borobova +9 more
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