Results 21 to 30 of about 557,393 (318)

Associations Between Methylation of Paternally Expressed Gene 3 (PEG3), Cervical Intraepithelial Neoplasia and Invasive Cervical Cancer. [PDF]

, 2013
Cytology-based screening for invasive cervical cancer (ICC) lacks sensitivity and specificity to discriminate between cervical intraepithelial neoplasia (CIN) likely to persist or progress from cases likely to resolve.
Bartlett, John A., Britta Swai, Smith Jennifer S., Obure, Joseph, Obure Joseph, Vasquez, Brandi, Nye, Monica D., Swai, Britta, Gammon, Marilie D, Hoyo Cathrine, Frances Wang, Vasquez Brandi, Zhiqing Huang, Oneko Olola, Overcash, Francine, Oneko, Olola, Vidal Adriana C., Brenda Hernandez, Bartlett John A., Gammon Marilie D., Smith, Jennifer S, Francine Overcash, Nye, Monica D, Brandi Vasquez, Monica D Nye, Joseph Obure, Marilie D Gammon, Huang Zhiqing, Swai Britta, Olola Oneko, Mlay Pendo, Hernandez, Brenda, Wang Frances, Hernandez Brenda, Hoyo, Cathrine, Adriana C Vidal, Mlay, Pendo, Murphy, Susan K, Murphy, Susan K., Vidal, Adriana C, Pendo Mlay, Susan K Murphy, Smith, Jennifer S., Cathrine Hoyo, Gammon, Marilie D., Nye Monica D., Jennifer S Smith, Murphy Susan K., Wang, Frances, John A Bartlett, Huang, Zhiqing, Overcash Francine, Vidal, Adriana C., Bartlett, John A   +53 more
core   +1 more source

Methylation of demethylavermectins [PDF]

Antimicrobial Agents and Chemotherapy, 1987
Demethylavermectins, which lack methyl groups on the oleandrose moiety, were fed to wild-type "Streptomyces avermitilis," which produces the normal avermectin components, and the bioconversion products were identified. The oleandrose units of the demethylavermectins were not methylated by the wild-type strain, but the C-5 of the macrolide ring was ...
M D, Schulman, C, Ruby
openaire   +2 more sources

Methylation Status of Imprinted Genes and Repetitive Elements in Sperm DNA from Infertile Males [PDF]

, 2011
Stochastic, environmentally and/or genetically induced disturbances in the genome-wide epigenetic reprogramming processes during male germ-cell development may contribute to male infertility.
Tresch, A., N. El Hajj, M. Schorsch, Haaf, T., Hahn, T., U. Zechner, E. Schneider, T. Hahn, T. Haaf, El Hajj, N., Gromoll, J., Schorsch, M., A. Tresch, Schneider, E., Zechner, Ulrich, J. Gromoll   +15 more
core   +1 more source

Apoptosis and DNA methylation [PDF]

, 2011
Epigenetic mechanisms assist in maintaining gene expression patterns and cellular properties in developing and adult tissues. The molecular pathology of disease states frequently includes perturbation of DNA and histone methylation patterns, which can ...
Meng, Huan X, Nestor, Colm, Reddington, James P, Richard R. Meehan, Harrison, David J, Dunican, Donncha S, Monika Madej, Hackett, James A, Dunican, Donncha S; id_orcid, James P. Reddington, Madej, Monika, Colm Nestor, Sari Pennings, Meehan, Richard R, Pennings, Sari, James A. Hackett, Huan X. Meng, David J. Harrison, Donncha S. Dunican   +18 more
core   +1 more source

Analysis of SDC2 and SEPT9 promoters methylation in plasma cfDNA to detect colorectal and precancerous lesions [PDF]

Exploration of Medicine
Aim: Analysis of circulating free DNA (cfDNA) is now broadly used to diagnose, assess treatment response, and recurrence of various tumor types. Detection of aberrant cfDNA methylation in plasma is considered as one of the promising approaches for early ...
Viktoria Borobova, Artem Aksamentov, Dmitry Sazonov, Vladimir Baklaushev, Dmitry Indinok, Ekaterina Valuyskikh, Alexandr Valuiskikh, Nina Oleynikova, Petr Laktionov, Sergey Kovalenko   +9 more
doaj   +1 more source

Race-specific alterations in DNA methylation among middle-aged African Americans and Whites with metabolic syndrome

Epigenetics, 2020
Metabolic syndrome (MetS) is a cluster of cardiometabolic risk factors for all-cause mortality, cardiovascular disease, and cancer. Identifying epigenetic alterations associated with MetS in African Americans (AAs) and Whites may provide insight into ...
Kumaraswamy Naidu Chitrala, Dena G. Hernandez, Michael A. Nalls, Nicolle A. Mode, Alan B. Zonderman, Ngozi Ezike, Michele K. Evans   +6 more
doaj   +1 more source

Promoter aberrant methylation status of ADRA1A is associated with hepatocellular carcinoma

Epigenetics, 2020
The aim of our study was to explore the relationship between the methylation status of the alpha-1A adrenergic receptor (ADRA1A) gene and hepatocellular carcinoma (HCC).
Guoqiao Chen, Xiaoxiao Fan, Yirun Li, Lifeng He, Shanjuan Wang, Yili Dai, Cui Bin, Daizhan Zhou, Hui Lin   +8 more
doaj   +1 more source

Turnover and function of DNA methylation at transcription factor binding sites [PDF]

, 2014
Cell type identity is largely determined by regulatory networks consistent of various transcription factors. Transcription factor activity requires interaction with DNA and thus critically depends on the accessibility of binding motifs.
Feldmann, Angelika
core   +1 more source

The Influence of Methylating Mutations on Acute Myeloid Leukemia: Preliminary Analysis on 56 Patients

Diagnostics, 2020
Acute myeloid leukemia (AML) is a hematologic malignancy characterized by abnormal proliferation and a lack of differentiation of myeloid blasts. Considering the dismal prognosis this disease presents, several efforts have been made to better classify it
Sergiu Pasca, Cristina Turcas, Ancuta Jurj, Patric Teodorescu, Sabina Iluta, Ionut Hotea, Anca Bojan, Cristina Selicean, Bogdan Fetica, Bobe Petrushev, Vlad Moisoiu, Alina-Andreea Zimta, Valentina Sas, Catalin Constantinescu, Mihnea Zdrenghea, Delia Dima, Ciprian Tomuleasa   +16 more
doaj   +1 more source

Fresh Insights Into SLC25A26: Potential New Therapeutic Target for Cancers: A Review

Oncology Reviews
SLC25A26 is the only known human mitochondrial S-adenosylmethionine carrier encoding gene. Recent studies have shown that SLC25A26 is abnormally expressed in some cancers, such as cervical cancer, low-grade glioma, non-small cell lung cancer, and liver ...
Yangheng Xu, Zhisheng Hong, Sheng Yu, Ronghan Huang, Kunqi Li, Ming Li, Sisi Xie, Lvyun Zhu   +7 more
doaj   +1 more source