Results 21 to 30 of about 426,231 (268)
DNA methylation profiles unique to Kalahari KhoeSan individuals
Epigenetics, 2021 Genomes of KhoeSan individuals of the Kalahari Desert provide the greatest understanding of single nucleotide diversity in the human genome. Compared with individuals in industrialized environments, the KhoeSan have a unique foraging and hunting ...
Alexander Goncearenco +7 more
doaj +1 more source
Differential methylation pattern in pubertal girls associated with biochemical premature adrenarche
Epigenetics, 2023 Biochemical premature adrenarche is defined by elevated serum DHEAS [≥40 μg/dL] before age 8 y in girls. This condition is receiving more attention due to its association with obesity, hyperinsulinemia, dyslipidemia, and polycystic ovary syndrome ...
Diana Ponce +9 more
doaj +1 more source
Epigenetics, 2022 Physical activity reduces risk of colon cancer by 20–30%. Aberrant methylation patterns are common epigenetic alterations in colorectal adenomas, and cancers and play a role in cancer initiation and progression.
Catherine Duggan +6 more
doaj +1 more source
Advanced Science, 2023 Dental pulp stem cells (DPSCs), characterized by easy availability, multi‐lineage differentiation ability, and high proliferation ability, are ideal seed cells for cartilage tissue engineering.
Qiannan Sun +7 more
doaj +1 more source
Methylation of demethylavermectins [PDF]
Antimicrobial Agents and Chemotherapy, 1987 Demethylavermectins, which lack methyl groups on the oleandrose moiety, were fed to wild-type "Streptomyces avermitilis," which produces the normal avermectin components, and the bioconversion products were identified. The oleandrose units of the demethylavermectins were not methylated by the wild-type strain, but the C-5 of the macrolide ring was ...
M D, Schulman, C, Ruby
openaire +2 more sources
Analysis of SDC2 and SEPT9 promoters methylation in plasma cfDNA to detect colorectal and precancerous lesions [PDF]
Exploration of MedicineAim: Analysis of circulating free DNA (cfDNA) is now broadly used to diagnose, assess treatment response, and recurrence of various tumor types. Detection of aberrant cfDNA methylation in plasma is considered as one of the promising approaches for early ...
Viktoria Borobova +9 more
doaj +1 more source
Epigenetics, 2020 Metabolic syndrome (MetS) is a cluster of cardiometabolic risk factors for all-cause mortality, cardiovascular disease, and cancer. Identifying epigenetic alterations associated with MetS in African Americans (AAs) and Whites may provide insight into ...
Kumaraswamy Naidu Chitrala +6 more
doaj +1 more source
Promoter aberrant methylation status of ADRA1A is associated with hepatocellular carcinoma
Epigenetics, 2020 The aim of our study was to explore the relationship between the methylation status of the alpha-1A adrenergic receptor (ADRA1A) gene and hepatocellular carcinoma (HCC).
Guoqiao Chen +8 more
doaj +1 more source
Diagnostics, 2020 Acute myeloid leukemia (AML) is a hematologic malignancy characterized by abnormal proliferation and a lack of differentiation of myeloid blasts. Considering the dismal prognosis this disease presents, several efforts have been made to better classify it
Sergiu Pasca +16 more
doaj +1 more source
Fresh Insights Into SLC25A26: Potential New Therapeutic Target for Cancers: A Review
Oncology ReviewsSLC25A26 is the only known human mitochondrial S-adenosylmethionine carrier encoding gene. Recent studies have shown that SLC25A26 is abnormally expressed in some cancers, such as cervical cancer, low-grade glioma, non-small cell lung cancer, and liver ...
Yangheng Xu +7 more
doaj +1 more source