Results 21 to 30 of about 607,486 (297)

Epigenetic regulation during fetal femur development: DNA methylation matters [PDF]

, 2013
Epigenetic modifications are heritable changes in gene expression without changes in DNA sequence. DNA methylation has been implicated in the control of several cellular processes including differentiation, gene regulation, development, genomic ...
Oreffo Richard O. C., Oreffo, Richard O. C., Antonio Gonzalez, González Martínez-Pedrayo, Antonio, Imagawa, K., Richard O C Oreffo, de Andrés María C., Gonzalez, A., Roach Helmtrud I., Wilson, David I., Kingham, Emmajayne, Oreffo, R.O., Kingham Emmajayne, Helmtrud I Roach, Oreffo, Richard O C, Gomez-Reino, J.J., Emmajayne Kingham, Kei Imagawa, María C de Andrés, Wilson, D.I., Roach, Helmtrud I, Wilson David I., de Andrés, María C., Imagawa, Kei, Roach, Helmtrud I., De Andrés González, Mª Carmen, Imagawa Kei, Wilson, David I, Neves, Nuno M., David I Wilson, Gonzalez, Antonio, Roach, H.I., Kingham, E., Gonzalez Antonio, de Andrés, M.C.   +34 more
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Associations Between Methylation of Paternally Expressed Gene 3 (PEG3), Cervical Intraepithelial Neoplasia and Invasive Cervical Cancer. [PDF]

, 2013
Cytology-based screening for invasive cervical cancer (ICC) lacks sensitivity and specificity to discriminate between cervical intraepithelial neoplasia (CIN) likely to persist or progress from cases likely to resolve.
Bartlett, John A., Britta Swai, Smith Jennifer S., Obure, Joseph, Obure Joseph, Vasquez, Brandi, Nye, Monica D., Swai, Britta, Gammon, Marilie D, Hoyo Cathrine, Frances Wang, Vasquez Brandi, Zhiqing Huang, Oneko Olola, Overcash, Francine, Oneko, Olola, Vidal Adriana C., Brenda Hernandez, Bartlett John A., Gammon Marilie D., Smith, Jennifer S, Francine Overcash, Nye, Monica D, Brandi Vasquez, Monica D Nye, Joseph Obure, Marilie D Gammon, Huang Zhiqing, Swai Britta, Olola Oneko, Mlay Pendo, Hernandez, Brenda, Wang Frances, Hernandez Brenda, Hoyo, Cathrine, Adriana C Vidal, Mlay, Pendo, Murphy, Susan K, Murphy, Susan K., Vidal, Adriana C, Pendo Mlay, Susan K Murphy, Smith, Jennifer S., Cathrine Hoyo, Gammon, Marilie D., Nye Monica D., Jennifer S Smith, Murphy Susan K., Wang, Frances, John A Bartlett, Huang, Zhiqing, Overcash Francine, Vidal, Adriana C., Bartlett, John A   +53 more
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Lysine 68 Methylation‐Dependent SOX9 Stability Control Modulates Chondrogenic Differentiation in Dental Pulp Stem Cells

Advanced Science, 2023
Dental pulp stem cells (DPSCs), characterized by easy availability, multi‐lineage differentiation ability, and high proliferation ability, are ideal seed cells for cartilage tissue engineering.
Qiannan Sun, Zimeng Zhuang, Rushui Bai, Jie Deng, Tianyi Xin, Yunfan Zhang, Qian Li, Bing Han   +7 more
doaj   +1 more source

The Dnmt3L ADD Domain Controls Cytosine Methylation Establishment during Spermatogenesis [PDF]

, 2015
A critical aspect of mammalian gametogenesis is the reprogramming of genomic DNA methylation. The catalytically inactive adaptor Dnmt3L is essential to ensuring this occurs correctly, but the mechanism by which it functions is unclear.
Robert J. Schmitz, Chad E. Niederhuth, Ooi, Steen KT, Stathopoulou, A, Richard G. Jenner, Steen K.T. Ooi, de Rooij, Dirk G, Tuna, Salih, Vlachogiannis, Georgios, Niederhuth, CE, Viiri, Keijo, Niederhuth, Chad E, Schmitz, RJ, Jenner, Richard G., Jenner, Richard G,, Vlachogiannis, G, Keijo Viiri, Tuna, S, Ooi, SK, Stathopoulou, Athanasia, Jenner, RG, Ooi, Steen K.T., de Rooij, DG, Dirk G. de Rooij, Schmitz, Robert J, de Rooij, Dirk G., Athanasia Stathopoulou, Salih Tuna, Niederhuth, Chad E., Schmitz, Robert J., Viiri, K, Ooi, Steen K. T., Georgios Vlachogiannis   +32 more
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Absolute quantitation of DNA methylation of 28 candidate genes in prostate cancer using pyrosequencing [PDF]

, 2011
This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.Aberrant DNA methylation plays a pivotal
Vasiljevic, N, Wu, KQ, Mao, XY, Xue, LY, Lorincz, AT, Berney, DM, Yu, YW, Kudahetti, SC, Brentnall, AR, Cuzick, J, Shaw, GL, Kim, DC, Beltran, L, Lu, YJ, Thorat, MA   +14 more
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Analysis of SDC2 and SEPT9 promoters methylation in plasma cfDNA to detect colorectal and precancerous lesions [PDF]

Exploration of Medicine
Aim: Analysis of circulating free DNA (cfDNA) is now broadly used to diagnose, assess treatment response, and recurrence of various tumor types. Detection of aberrant cfDNA methylation in plasma is considered as one of the promising approaches for early ...
Viktoria Borobova, Artem Aksamentov, Dmitry Sazonov, Vladimir Baklaushev, Dmitry Indinok, Ekaterina Valuyskikh, Alexandr Valuiskikh, Nina Oleynikova, Petr Laktionov, Sergey Kovalenko   +9 more
doaj   +1 more source

Race-specific alterations in DNA methylation among middle-aged African Americans and Whites with metabolic syndrome

Epigenetics, 2020
Metabolic syndrome (MetS) is a cluster of cardiometabolic risk factors for all-cause mortality, cardiovascular disease, and cancer. Identifying epigenetic alterations associated with MetS in African Americans (AAs) and Whites may provide insight into ...
Kumaraswamy Naidu Chitrala, Dena G. Hernandez, Michael A. Nalls, Nicolle A. Mode, Alan B. Zonderman, Ngozi Ezike, Michele K. Evans   +6 more
doaj   +1 more source

Methylation of demethylavermectins [PDF]

Antimicrobial Agents and Chemotherapy, 1987
Demethylavermectins, which lack methyl groups on the oleandrose moiety, were fed to wild-type "Streptomyces avermitilis," which produces the normal avermectin components, and the bioconversion products were identified. The oleandrose units of the demethylavermectins were not methylated by the wild-type strain, but the C-5 of the macrolide ring was ...
M D, Schulman, C, Ruby
openaire   +2 more sources

Promoter aberrant methylation status of ADRA1A is associated with hepatocellular carcinoma

Epigenetics, 2020
The aim of our study was to explore the relationship between the methylation status of the alpha-1A adrenergic receptor (ADRA1A) gene and hepatocellular carcinoma (HCC).
Guoqiao Chen, Xiaoxiao Fan, Yirun Li, Lifeng He, Shanjuan Wang, Yili Dai, Cui Bin, Daizhan Zhou, Hui Lin   +8 more
doaj   +1 more source

Turnover and function of DNA methylation at transcription factor binding sites [PDF]

, 2014
Cell type identity is largely determined by regulatory networks consistent of various transcription factors. Transcription factor activity requires interaction with DNA and thus critically depends on the accessibility of binding motifs.
Feldmann, Angelika
core   +1 more source