Results 201 to 210 of about 443,290 (339)

Regulation of transcriptional homeostasis by DNA methylation upon genome duplication in pak choi. [PDF]

open access: yesMol Hortic
Ma M   +9 more
europepmc   +1 more source

Methionine in pattern control of Hydra

open access: yesOpen Life Sciences, 2009
Berking Stefan   +3 more
doaj   +1 more source

The Methylation of Lysine Residues in Protein

open access: hybrid, 1966
Donald G. Comb   +2 more
openalex   +1 more source

Enhancing Prime Editing Efficiency Through Modulation of Methylation on the Newly Synthesized DNA Strand and Prolonged Expression

open access: yesAdvanced Science, EarlyView.
Prime editors (PEs) enhance gene editing precision but face repair mechanism limitations. DNA methylation (CpG sites) and de novo methyltransferases (DNMT3A/DNMT3B) boost PE efficiency. We developed an episomal PE system (epiPE) using EBNA1/oriP to sustain expression and methylation.
Xiaosong Han   +15 more
wiley   +1 more source

A diagnostic model for non-invasive urothelial cancer early detection based on methylation of urinary tumor DNA. [PDF]

open access: yesCancer Cell Int
Wu N   +10 more
europepmc   +1 more source

STING Agonists and How to Reach Their Full Potential in Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
STING agonists show promise in preclinical studies in boosting an anti‐tumor response using the immune system. However, different limitations remain, and future research is needed to better understand how STING activation impacts the tumor microenvironment, identify effective combination strategies, and determine the best tumor types for STING agonist ...
Laura Gehrcken   +3 more
wiley   +1 more source

The Enzymatic Methylation of Ribonucleic Acid and Deoxyribonucleic Acid

open access: hybrid, 1965
Jerard Hurwitz   +3 more
openalex   +1 more source

AKT1E17K‐Interacting lncRNA SVIL‐AS1 Promotes AKT1 Oncogenic Functions by Preferentially Blocking AKT1E17K Dephosphorylation

open access: yesAdvanced Science, EarlyView.
Wang et al. discover a novel lncRNA regulator of mutant oncoprotein which prevents AKT1E17K dephosphorylation. SVIL‐AS1 overexpression correlates with poor prognosis of breast cancer patients. It interacts with AKT1E17K protein and impedes PP2A holoenzyme from dephosphorylating AKT1 by blocking the binding of the regulatory subunit PPP2R2A to AKT1 ...
Jingyi Wang   +8 more
wiley   +1 more source

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