Results 251 to 260 of about 652,669 (356)

Enzymatic Methylation of Homocysteine by a Synthetic Tetrahydrofolate Derivative

, 1961
Warwick Sakami, I Ukstins
openalex   +1 more source

Loss of STARD7 Triggers Metabolic Reprogramming and Cell Cycle Arrest in Breast Cancer

Advanced Science, EarlyView.
Breast cancer cells undergo metabolic and transcriptomic reprogramming to support aberrant cell proliferation. Their mitochondria rely on the transfer of phosphatidylcholine from the endoplasmic reticulum to their membranes by STARD7, a candidate upregulated in breast cancer, to be functional.
Ewelina Dondajewska, Paula Allepuz‐Fuster, Chloé Maurizy, Alexandre Hego, Sandra Ormenese, Quentin Lion, Arnaud Blomme, Pierre Close, Arnaud Lavergne, Latifa Karim, Marc Thiry, Ivan Nemazanyy, Roopesh Krishnankutty, Jair Marques Jr, Alex von Kriegsheim, Nathaniel F. Henneman, Ganna Panasyuk, Kateryna Shostak, Alain Chariot   +18 more
wiley   +1 more source

The advances of DNA methylation in the liquid biopsy for the detection of lung cancer. [PDF]

Front Oncol
Chen Y, Peng S, Wang C.
europepmc   +1 more source

Mitochondrial Regulation of CD8⁺ T Cells: Mechanisms and Therapeutic Modulation

Advanced Science, EarlyView.
This article comprehensively explores the pivotal role of mitochondrial function in CD8⁺ T cell immunotherapy. It highlights how mitochondrial dynamics regulate T cell activation, differentiation, and persistence, and how mitochondrial dysfunction leads to immune exhaustion and impaired antitumor/antiviral responses.
Xu Chen, Pei Lin, Ye Lu, Jiarong Zheng, Yunfan Lin, Zihao Zhou, Li Cui, Xinyuan Zhao   +7 more
wiley   +1 more source

From trauma to resilience: psychological and epigenetic adaptations in the third generation of holocaust survivors. [PDF]

Sci Rep
Oren G, Shoshani A, Samra NN, Verbeke WJ, Vrticka P, Aisnberg-Shafran D, Ein-Dor T.   +6 more
europepmc   +1 more source

NPR1 Promotes Lipid Droplet Lipolysis to Enhance Mitochondrial Oxidative Phosphorylation and Fuel Gastric Cancer Metastasis

Advanced Science, EarlyView.
NPR1 induces lipolysis of stored lipid droplet and enhances mitochondrial oxidative phosphorylation to fuel gastric cancer metastasis. Specifically, NPR1‐mediated activation of PKG directly phosphorylates and activates HSL at Ser855 and Ser951, thereby driving lipolytic processes.
Huafeng Fu, Jie Zhang, Hengxing Chen, Haobin Hou, Huanjie Chen, Rongman Xie, Yanlei Chen, Jian Zhang, Dehua Liu, Leping Yan, Rui L. Reis, Joaquim M. Oliveira, Yulong He, Li Zhong, Qinbo Cai, Dongjie Yang   +15 more
wiley   +1 more source

The Spectrum of IDH- and H3-Wildtype High-Grade Glioma Subgroups Occurring across Teenage and Young Adult Patient Populations. [PDF]

Clin Cancer Res
Pereira R, Mackay A, Grabovska Y, Bradley A, Bloom T, Nicoll J, Boche D, Procter J, Maybury M, Schagen J, Walker L, Roncaroli F, Karabatsou K, Ogunbiyi O, van Dalen T, Sidpra J, Rossi S, Miele E, Ziegler DS, Shi Z, Jacques TS, Hargrave D, Zebian B, Bleil C, Yates J, Norton E, Mandeville H, Creak A, Welsh L, Marshall L, Carceller F, Vaidya SJ, Reisz Z, Al-Sarraj S, Mastronuzzi A, Carai A, Vinci M, Kurian KM, Ng HK, Brandner S, Jones C, Clarke M.   +41 more
europepmc   +1 more source

Histone methylation: a dynamic mark in health, disease and inheritance

Nature reviews genetics, 2012
E. L. Greer, Yang Shi
semanticscholar   +1 more source

Plasmonic Molecular Entrapment for Label‐Free Methylated DNA Detection and Machine‐Learning Assisted Quantification

Advanced Science, EarlyView.
Plasmonic molecular entrapment (PME) is label‐free detection and quantification method for DNA methylation. This technique provides direct hotspot site generation around target analytes, overcoming mismatch geometrical properties. The PME demonstrates superior SERS performance and quantification capability, offering promising potential for epigenetic ...
Muhammad Shalahuddin Al Ja'farawy, Vo Thi Nhat Linh, Chaewon Mun, Jun‐Yeong Yang, Jun Young Kim, Rowoon Park, Sung‐Gyu Park, Dong‐Ho Kim, Min‐Young Lee, Ho Sang Jung   +9 more
wiley   +1 more source

Pharmacoepigenetics in schizophrenia: Predicting drug response. [PDF]

World J Psychiatry
Yıldırım SA, Dal I, Özkan-Kotiloğlu S, Baskak B, Kaya-Akyüzlü D.   +4 more
europepmc   +1 more source