Results 61 to 70 of about 911,489 (397)
A METTL3-METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation
Nature Chemical Biology, 2013 N6-methyladenosine (m6A) is the most prevalent and reversible internal modification in mammalian messenger and non-coding RNAs. We report here that human METTL14 catalyzes m6A RNA methylation.
Jianzhao Liu +12 more
semanticscholar +1 more source
E3S Web of Conferences, 2013 An examination of the distribution of mercury and methylmercury across estuarine ecosystems in the northeast USA was completed under a number of projects. Sites ranged from Maine to the Chesapeake Bay and included both pristine and contaminated sites. In
Schartup A. T. +3 more
doaj +1 more source
lncRNA Mirt2 upregulates miR‐1246 through methylation to suppress LPS‐induced lung cell apoptosis
Immunity, Inflammation and Disease, 2021 Introduction Long noncoding RNA Mirt2 has been proven to be a suppressor of lipopolysaccharide (LPS) (a key player in sepsis)‐induced inflammation responses. Therefore, Mirt2 may also participate in sepsis.
Xuwen Xu +3 more
doaj +1 more source
Assessing the preservation of cytosine methylation in ancient DNA from five prehistoric Native American populations [PDF]
, 2015 textCytosine methylation of CpG dinucleotides is an important epigenetic mark that regulates gene expression in humans. While methylation patterns in extant populations have been widely studied, few studies have attempted to analyze methylation in ...
Smith, Ricky Wayne Aldon
core +1 more source
Frontiers in Genetics, 2020 There are associations between DNA methylation and the expression of long non-coding RNA (lncRNA), also known as lncRNA expression quantitative trait methylations (lnc-eQTMs). Lnc-eQTMs may induce a wide range of carcinogenesis pathways.
Xiaohong Wu +9 more
doaj +1 more source
Modeling DNA methylation dynamics with approaches from phylogenetics [PDF]
, 2014 Methylation of CpG dinucleotides is a prevalent epigenetic modification that is required for proper development in vertebrates, and changes in CpG methylation are essential to cellular differentiation.
Capra, John A., Kostka, Dennis
core +1 more source
Methylation of demethylavermectins [PDF]
Antimicrobial Agents and Chemotherapy, 1987 Demethylavermectins, which lack methyl groups on the oleandrose moiety, were fed to wild-type "Streptomyces avermitilis," which produces the normal avermectin components, and the bioconversion products were identified. The oleandrose units of the demethylavermectins were not methylated by the wild-type strain, but the C-5 of the macrolide ring was ...
M D Schulman, C Ruby
openaire +3 more sources
Gene-specific methylation profiles in BRCA-mutation positive and BRCA-mutation negative male breast cancers [PDF]
, 2018 Male breast cancer (MBC) is a rare disease. Due to its rarity, MBC research and clinical approach are mostly based upon data derived from female breast cancer (FBC). Increasing evidence indicate that on molecular level MBC may be an heterogeneous disease
Bianchi, Simonetta +8 more
core +2 more sources
The Toxicity of Methylal [PDF]
Occupational and Environmental Medicine, 1951 dimethoxymethane, formaldehyde dimethyl acetal and m?thyl?ne dimethyl ether, the simplest of the group of acet?is, can be prepared very simply by the interaction of formaldehyde and methanol catalyzed by dry hydrogen chloride or even by calcium chloride, ft is a clear, thin, mobile liquid, lighter than water, and soluble in water to the extent of one ...
Frank L. Weaver +3 more
openaire +3 more sources
DNA methylation arrays as surrogate measures of cell mixture distribution
BMC Bioinformatics, 2012 There has been a long-standing need in biomedical research for a method that quantifies the normally mixed composition of leukocytes beyond what is possible by simple histological or flow cytometric assessments.
E. Houseman +7 more
semanticscholar +1 more source