Results 81 to 90 of about 49,335 (246)
KPNA2 Drives Immunosuppression in Ovarian Cancer via CCL2/CCR2‐Dependent MDSC Recruitment
KPNA2 drives intratumoral MDSC accumulation and immunosuppression in ovarian cancer via the NF‐κB/CCL2/CCR2 axis. Mechanistically, KPNA2 facilitates NF‐κB/p65 nuclear translocation and induces CCL2 transcription, recruiting MDSCs to establish an immunosuppressive microenvironment.
Qingli Li +8 more
wiley +1 more source
Crioanalgesia: una técnica novedosa Cryoanalgesia: New anesthetic technique
Se describe una novedosa técnica anestésica denominada crioanalgesia, que constituye una alternativa para la cirugía de catarata con facoemulsificación.
Pamy Stolik Pérez +5 more
doaj
Oropharyngeal dysphagia is a common condition among older adults and individuals with neurological disorders, necessitating the use of texture-modified foods (TMFs) to ensure safe swallowing; however, reheating often leads to syneresis and structural ...
Narmatha Maran +2 more
doaj +1 more source
Additive manufacturing processes based on fused deposition modeling (FDM) typically use thermoplastic materials like ABS, PLA, or nylon to fabricate parts layer-by-layer. In order to build a part successfully with complex features such as pores or holes or irregular shapes, the build part requires support structures to hold the deposited material and ...
openaire +3 more sources
TGF‐β signaling regulates extracellular vesicle (EV) release in cancer cells by modulating the expression and activity of genes associated with EV biogenesis. The TGF‐β‐induced upregulation of RAB4A expression facilitates fast endosomal recycling, a process that limits the fusion of multivesicular bodies with the plasma membrane and EV secretion. Hence,
Dorival Mendes Rodrigues‐Junior +5 more
wiley +1 more source
Corneal cross-linking (CXL) has become the most common way of managing keratectasia. To date, the Dresden protocol (G. Wollensak et al., 2003) has acquired many modifications, in which the composition of the applied agents or modes of CXL procedure have ...
M. M. Bikbov +5 more
doaj +1 more source
Macromolecule‐dependent increases in extracellular fluid viscosity alter cell phenotype. These distinct macromolecules create different extracellular environments that modulate cell morphology and mechanoprotein expression, migration and invasion capacity, and cellular mechanical properties.
Ian M. Smith +6 more
wiley +1 more source
As a result of the work performed, a method for synthesizing selenium nanoparticles stabilized with methylcellulose was developed and optimized.
A.A. Blinova +5 more
doaj +1 more source
ABSTRACT Aim Hypoxic preconditioning of cells holds promise for regenerative therapies, yet identifying effective and safe methods for clinical application remains challenging. We aimed to determine optimal hypoxia‐mimetic small molecules (SMs) that stabilize hypoxia‐inducible factor‐1α (HIF‐1α) and their dosages for hypoxic preconditioning in stem ...
Hong Wang +9 more
wiley +1 more source
Characterisation of human hair follicle development
Schematic of hair follicle development in human skin. Hair follicle primordia of similar sizes, but different densities, are laid out across the skin. The distinction between terminal and vellus hair sites is not obvious at early stages of hair follicle development.
Zoe R. Sudderick +4 more
wiley +1 more source

