Results 61 to 70 of about 95,722 (324)

Deciphering the Role of Cancer Stem Cells in Breast Cancer Brain Colonization Using a Novel Patient‐Derived Model

Advanced Healthcare Materials, EarlyView.
This study shows that stem‐like cells isolated from breast cancer brain metastases drive the spread and growth of tumors in the brain. Among them, a highly adhesive subgroup initiates metastasis and resists many drugs. By closely reflecting patient tumors, these models help identify new targets and improve the development of effective treatments ...
Stefania Faletti, Cristina Richichi, Daniela Osti, Elena Ceccacci, Giovanni Bertalot, Camilla Cerutti, Giuseppina Giardina, Adriana Marinaro, Brunella Costanza, Valentina Gambino, Elena Zaccheroni, Daniela Tosoni, Maria G. Filippone, Marcello Del Corvo, Yinxiu Zhan, Teresa Gravina, Davide Corà, Monica Patanè, Bianca Pollo, Maria Giovanna Jodice, Salvatore Pece, Babette B. Weksler, Ignacio A. Romero, Pierre‐Olivier Couraud, Elisabetta Munzone, Massimiliano Del Bene, Francesco DiMeco, Giuliana Pelicci   +27 more
wiley   +1 more source

Hydrogels Under Superchaotropic Control: Polyoxometalate Stabilization and pH‐Responsive Crosslinking in Cellulose Ether Solutions

Angewandte Chemie, EarlyView.
Superchaotropic binding of Keggin polyoxometalates (POMs) to non‐ionic biopolymers like cellulose ethers (CEs) stabilizes otherwise hydrolytically unstable POMs in aqueous solution and allows conversion of pH‐nonresponsive polymers into pH‐responsive soft materials. The pH‐driven conversion from plenary to lacunary POMs switches superchaotropic binding
Vighnesh B. Lokare, Amina Ledinic, Nina Wehr, Max Hohenschutz   +3 more
wiley   +2 more sources

Mechanical, thermal, and barrier properties of methylcellulose/cellulose nanocrystals nanocomposites

Polímeros, 2014
In this work, the effects of incorporating cellulose nanocrystals from soy hulls (WSH30) on the mechanical, thermal, and barrier properties of methylcellulose (MC) nanocomposites were evaluated.
Hudson Alves Silvério, Wilson Pires Flauzino Neto, Ingrid Souza Vieira da Silva, Joyce Rover Rosa, Daniel Pasquini, Rosana Maria Nascimento de Assunção, Hernane da Silva Barud, Sidney José Lima Ribeiro   +7 more
doaj   +1 more source

Effect of various additives on the properties of the films and coatings derived from hydroxypropyl methylcellulose—A review

Food Science & Nutrition, 2019
Edible films and coating materials are commonly used as appropriate packaging materials to extend the shelf life of fresh food. Due to all their properties, edible film and coating materials have been received much attention.
R. Ghadermazi, S. Hamdipour, Kambiz Sadeghi, Rojin Ghadermazi, A. Khosrowshahi Asl   +4 more
semanticscholar   +1 more source

Tuning the Testicular Microenvironment for Enhancing Human Sertoli Cells Maturation and Functionality In Vitro

Advanced Healthcare Materials, EarlyView.
An in vitro testicular model is developed by generating connective tissue equivalents from human dermal fibroblast‐derived microtissues and coupling them with human Sertoli cells or human Sertoli cell spheroids. This engineered microenvironment supports Sertoli cell maturation and functionality, providing a promising platform for studying human ...
Annachiara Scalzone, Giorgia Imparato, Chiara Ausilio, Valentina Mollo, Paolo Antonio Netti   +4 more
wiley   +1 more source

Oxygen Supply of Islets of Langerhans by Photosynthetically Active Microalgae in Bioprinted Co‐Cultures Maintains Their Function in a Hypoxic Environment

Advanced Healthcare Materials, EarlyView.
This study developed a bioprinted co‐culture system embedding rat pancreatic islets and Scenedesmus sp. microalgae spatially defined in close vicinity. Red light was found optimal to ensure microalgal photosynthesis while maintaining islet viability and functionality. A tailored co‐culture medium supported both cell types.
Finn Dani, Sarah Duin, Ashwini Rahul Akkineni, Susann Lehmann, Barbara Ludwig, Michael Kühl, Michael Gelinsky, Anja Lode   +7 more
wiley   +1 more source

Stable Protein‐Based G‐Quadruplex‐Derived Supramolecular Bioinks as Tunable ECM‐Mimetic Constructs Assembled by Combining Non‐Covalent and Covalent Strategies

Advanced Materials, EarlyView.
Harnessing the synergistic interplay of supramolecular self‐assembly, under macromolecular crowding conditions, and enzymatic‐mediated covalent crosslinking toward a stable protein‐based G‐quadruplex‐derived supramolecular bioink. This bioinspired strategy enables the biofabrication of complex and tunable ECM‐mimetic constructs, providing a platform ...
Vera Sousa, Rita Sobreiro‐Almeida, Bart W. L. van den Bersselaar, E. W. Meijer, Ghislaine Vantomme, João Borges, João F. Mano   +6 more
wiley   +1 more source

Strength and Structure: The Role of Different Hydrogel Matrices in Determining the Textural Properties of Jojoba Oil Bigels

Scientia Pharmaceutica
Jojoba oil is a well-established skin-beneficial liquid wax with high value in topical formulations. Bigels, as preferred semi-solid dosage forms, serve as versatile platforms by incorporating hydrogels and oleogels to leverage their advantages and ...
Yoana Sotirova
doaj   +1 more source

Droplet Microfluidics-Assisted Fabrication of Magnetite Nanoparticle Hybrid Microgels for Facile Protein Immobilization. [PDF]

Chembiochem
We present a versatile approach to uniform hybrid microgels containing magnetite nanoparticles (MNPs). Methylcellulose stabilizes MNPs in pre‐hydrogel suspensions, enabling microfluidic processing. Functionalization with biotin yields an experimental platform for enzyme immobilization, shown by immobilizing streptavidin‐horseradish peroxidase (HRP) and
Neuendorf TA, Kaufmann A, Wilson RJ, Blank KG, Thiele J.   +4 more
europepmc   +2 more sources

p53 independent epigenetic-differentiation treatment in xenotransplant models of acute myeloid leukemia [PDF]

, 2011
Suppression of apoptosis by TP53 mutation contributes to resistance of acute myeloid leukemia (AML) to conventional cytotoxic treatment. Using differentiation to induce irreversible cell cycle exit in AML cells could be a p53-independent treatment ...
Anjali Advani, Edward Copelan, James C. Mulloy, PhD, Jaroslaw Maciejewski, Kevin Link, Kwok-Peng Ng, Matt Kalaycio, Mikkael Sekeres, Quteba Ebrahem, Reda Mahfouz, Ronald Sobecks, Soledad Negrotto, Tomas Radivoyevitch, Xiaorong Gu, Yogen Saunthararajah, Zhenbo Hu   +15 more
core   +2 more sources