Results 41 to 50 of about 8,425 (182)

Features of Autoimmune Hepatitis in Patients With Drug-induced Liver Injury [PDF]

, 2017
BACKGROUND & AIMS: Drug-induced liver injury (DILI) has features similar to those of other liver diseases including autoimmune hepatitis (AIH). We aimed to characterize the clinical and autoimmune features of liver injury caused by nitrofurantoin ...
Chalasani, Naga, de Boer, Ynto S., Drug-Induced Liver Injury Network., Hoofnagle, Jay H., Kleiner, David E., Kosinski, Andrzej S., Long, Nanye, Urban, Thomas J., Zhao, Zhen   +8 more
core   +2 more sources

Different culture media containing methyldopa for melanin production by Cryptococcus species

Revista da Sociedade Brasileira de Medicina Tropical, 2011
INTRODUCTION: Melanin production by species of Cryptococcus is widely used to characterize C. neoformans complex in mycology laboratories. This study aims to test the efficacy of methyldopa from pharmaceutical tablet as a substrate for melanin production,
Ralciane de Paula Menezes, Mário Paulo Amante Penatti, Reginaldo dos Santos Pedroso   +2 more
doaj   +1 more source

Comparison of Lasix and Methyldopa in Controlling Hypertension in preeclampsia patients: A Double-Blind Randomized Clinical Trial

Men's Health Journal, 2020
Introduction: Preeclampsia is a specific gestational syndrome that reduces organ perfusion due to vascular spasm and endothelial activation. Despite the use of magnesium sulfate, the patient's blood pressure sometimes remains uncontrolled, and therefore,
Setareh Siamansoori, Elahe Afshari, Maryam Palizdar, Mohammad Ali Hosseini   +3 more
doaj   +1 more source

Methodical approaches to bioassay of substances containing unstable functional groups [PDF]

, 2018
This article describes the method development approaches for bioassay of substances containing unstable functional groups and forming unstable metabolites using the example of mycophenolic acid, methyldopa and mebeverine ...
Dzhurko, Yu. A., Khokhlov, A. L., Shitov, L. N., Shitova, A. A., Yaichkov, I. I.   +4 more
core   +2 more sources

Complement Receptor 3 Mediates HIV-1 Transcytosis across an Intact Cervical Epithelial Cell Barrier: New Insight into HIV Transmission in Women

mBio, 2022
Transmission of HIV across the mucosal surface of the female reproductive tract to engage subepithelial CD4-positive T cells is not fully understood. Cervical epithelial cells express complement receptor 3 (CR3) (integrin αMβ2 or CD11b/CD18).
Christopher J. Day, Rachael L. Hardison, Belinda L. Spillings, Jessica Poole, Joseph A. Jurcisek, Johnson Mak, Michael P. Jennings, Jennifer L. Edwards   +7 more
doaj   +1 more source

A rare case of alpha-methyldopa-induced hepatitis in pregnancy [PDF]

Srpski Arhiv za Celokupno Lekarstvo
Introduction. There are three groups of disorders during pregnancy: disorders specific for pregnancy that resolve spontaneously or soon after delivery, acute hepatic disorders coinciding with pregnancy, and chronic disorders.
Likić-Lađević Ivana, Petronijević Miloš, Vrzić-Petronijević Svetlana, Beleslin Aleksandra, Dugalić Stefan   +4 more
doaj   +1 more source

Interaction Between NOS3 and HMOX1 on Antihypertensive Drug Responsiveness in Preeclampsia [PDF]

Revista Brasileira de Ginecologia e Obstetrícia, 2020
Objective We examined the interaction of polymorphisms in the genes heme oxygenase- 1 (HMOX1) and nitric oxide synthase (NOS3) in patients with preeclampsia (PE) as well as the responsiveness to methyldopa and to total antihypertensive therapy. Methods
Valeria Cristina Sandrim, Marcelo Rizzatti Luizon, Eliane Pilan, Mayara Caldeira-Dias, Fernanda Borchers Coeli-Lacchini, Georgia Kors, Iuly Berndt, Riccardo Lacchini, Ricardo Carvalho Cavalli   +8 more
doaj   +1 more source

Analytical Investigation of the Possible Chemical Interaction of Methyldopa with Some Reducing Carbohydrates Used as Pharmaceutical Excipients [PDF]

Advanced Pharmaceutical Bulletin, 2018
Purpose: Assessment of drug substance and excipients compatibility is an important issue during pre-formulation studies as well as the quality control of pharmaceutical dosage forms.
Mohammad Reaz Siahi, Soma Rahimi, Farnaz Monajjemzadeh   +2 more
doaj   +1 more source

Influence of Tropical Climate Conditions on the Quality of Antihypertensive Drugs from Rwandan Pharmacies [PDF]

, 2009
The objective of this study was to assess the quality of antihypertensive drugs and to investigate the influence of tropical storage conditions. Drug content and in vitro dissolution tests were performed on 10 test formulations (from Rwanda) and 6 ...
Cosijns, An, Pringels, Eveline, Remon, Jean Paul, Twagirumukiza, Marc, Van Bortel, Lucas, Vervaet, Chris   +5 more
core   +2 more sources

DETERMINAÇÃO ESPECTROFOTOMÉTRICA DE METILDOPA EM ENSAIO DE DISSOLUÇÃO DE COMPRIMIDOS UTILIZANDO EXTRATO DE RABANETE COMO FONTE DE PEROXIDASE

Química Nova, 2015
An enzymatic spectrophotometric method for the determination of methyldopa in a dissolution test of tablets was developed using peroxidase from radish (Raphanus sativus).
Natielle Gianine Bueno, Airton Vicente Pereira   +1 more
doaj   +1 more source