Results 1 to 10 of about 9,036 (155)
Methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism in psoriasis in southern Turkey [PDF]
Anais Brasileiros de Dermatologia, 2016 : Background: Psoriasis is a multigenic and multifactorial dermatological disease linked to cardiovascular diseases. Increased levels of homocysteine in patients with psoriasis have been demonstrated in many studies.
Muzeyyen Izmirli +7 more
doaj +4 more sources
DISTRIBUTION OF MTHFR C677T, A1298C POLYMORDHISMS, AND MTRR A66G POLYMORPHISMS IN HAN WOMEN IN JIA COUNTY, CHINA [PDF]
精准医学杂志, 2023 Objective To analyze the distribution characteristics of the gene polymorphisms of key enzymes related to folate metabolism [5,10-methylenetetrahydrofolate reductase (MTHFR) and methionine synthase reductase (MTRR)] in women of reproductive age of the ...
LI Huicong, WU Hongguo, LU Yanqiang, WANG Yanchao, WANG Qiuju, HU Jifang, YANG Q
doaj +1 more source
International Journal of Molecular Sciences, 2023 Methylenetetrahydrofolate reductase (MTHFR) is a key regulatory enzyme in the one-carbon cycle. This enzyme is essential for the metabolism of methionine, folate, and RNA, as well as for the production of proteins, DNA, and RNA.
Emilia Zarembska +2 more
semanticscholar +1 more source
Disease Markers, 2022 Methylenetetrahydrofolate reductase (MTHFR) is a critical rate-limiting enzyme in the homocysteine/methionine metabolism pathway that is implicated in the pathogenesis and progression of autoimmune diseases.
Mao Lu +5 more
semanticscholar +1 more source
Van Tıp Dergisi, 2022 INTRODUCTION: In this study, we aimed to investigation of the relationship between MTHFR C677T gene variation and serum copper levels in patients diagnosed with Parkinson's.
Arzu Ay, Nevra Alkanli, Sibel Guler
doaj +1 more source
Journal of clinical laboratory analysis (Print), 2021 Homocysteine assessment has been proposed as a potential predictive biomarker for the severity of COVID‐19 infection. The purpose of this review was to analyze the correlation between the prevalence of MTHFR C677 T gene polymorphism and COVID‐19 ...
G. Ponti +7 more
semanticscholar +1 more source
International Journal of Molecular Sciences, 2021 Methylenetetrahydrofolate reductase (MTHFR) is a key enzyme in the folate metabolic pathway, and its loss of function through polymorphisms is often associated with human conditions, including cancer, congenital heart disease, and Down syndrome. MTHFR is
Kim Kiat Lim +6 more
semanticscholar +1 more source
Association Study between Folate Pathway Gene Single Nucleotide Polymorphisms and Gastric Cancer in Koreans [PDF]
Genomics & Informatics, 2012 Gastric cancer is ranked as the most common cancer in Koreans. A recent molecular biological study about the folate pathway gene revealed the correlation with a couple of cancer types.
Jae-Young Yoo +6 more
doaj +1 more source
Methylation patterns of methylenetetrahydrofolate reductase gene promoter in infertile males
Andrologia, 2020 Errors of folate/homocysteine pathways which are critical for transferring methyl groups have been suggested to affect male fertility. We aimed to evaluate the methylation patterns of the promoter of methylenetetrahydrofolate reductase (MTHFR) gene in ...
T. Kulac +5 more
semanticscholar +1 more source
Scientific Reports, 2019 Methylenetetrahydrofolate reductase (MTHFR) catalyzes the irreversible conversion of 5,10-methylene-tetrahydrofolate (THF) to 5-methyl-THF, thereby committing one-carbon units to the methionine cycle.
Yuxiang Zheng +6 more
semanticscholar +1 more source