Increasing trend of sensitization to Methylchloroisothiazolinone/methylisothiazolinone (MCI/MI) [PDF]
Anais Brasileiros de Dermatologia, 2014 Recent reports have shown increased sensitization to Methylchloroisothiazolinone/methylisothiazolinone. We report a retrospective study conducted at the Hospital das Clínicas - UFMG, based on the results of patch tests with the Brazilian standard series,
Maria Antonieta Rios Scherrer +1 more
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Molecules, 2022 The electrochemical properties of methylisothiazolinone (MIT), the most widely used preservative, were investigated by cyclic (CV) and differential pulse voltammetry (DPV) to develop a new method for its determination. To our knowledge, this is the first
Magdalena Jakubczyk +3 more
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Methylchloroisothiazolinone/Methylisothiazolinone and Methylisothiazolinone Sensitivity in Hungary [PDF]
Dermatology Research and Practice, 2016 Background. Due to allowing of methylisothiazolinone (MI) in cosmetics, cleaning products, and paints, an epidemic of MI-hypersensitivity emerged. Patch testing Kathon CG® (3:1 mixture of methylchloroisothiazolinone and methylisothiazolinone, MCI/MI ...
Györgyi Pónyai +2 more
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Molecules, 2023 Isothiazolinone preservatives (methylisothiazolinone (MIT) and methylchloroisothiazolinone (CMIT) are commonly used in cosmetics, industrial and household products. However, these isothiazolinone derivatives are known to cause allergic contact dermatitis.
Samyah Alanazi +8 more
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Crystal Structure of the Biocide Methylisothiazolinone [PDF]
CrystalsMethylisothiazolinone (MIT) is widely used as a biocide in numerous personal care products, glass-cleaning liquids, paints, and industrial applications.
Richard Goddard +3 more
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Methylisothiazolinone: An Emergent Allergen in Common Pediatric Skin Care Products [PDF]
Dermatology Research and Practice, 2014 Recalcitrant dermatitis, such as that of the hands, face, or genitals, may be due to allergic contact dermatitis (ACD) from ingredients in seemingly innocuous personal care products.
Megan J. Schlichte, Rajani Katta
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The Contact Allergen Methylisothiazolinone (MIT) is a Potent Activator of the TRPA1 Ion Channel [PDF]
Pharmacology Research & PerspectivesMethylisothiazolinone (MIT) is a known inducer of allergic contact dermatitis that is used as a preservative and a biocide in consumer products. Transient receptor potential ankyrin 1 (TRPA1) is a non‐selective cation channel expressed in neurons and in ...
Ilari Mäki‐Opas +4 more
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Ecotoxicology and Environmental SafetyMouse strain and sex variability may provide a better understanding of the isothiazolinone-associated respiratory toxicity profile; however, this remains poorly understood.
Mi-Kyung Song +5 more
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Trends in the prevalence of methylchloroisothiazolinone/methylisothiazolinone contact allergy in North America and Europe [PDF]
, 2023 Importance: The common use of isothiazolinones as preservatives is a global cause of allergic contact dermatitis. Differences in allowable concentrations of methylisothiazolinone (MI) exist in Europe, Canada, and the US.
Johnston, Graham
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Eye irritation tests of polyhexamethylene guanidine phosphate (PHMG) and chloromethylisothiazolinone/methylisothiazolinone (CMIT/MIT) using a tissue model of reconstructed human cornea-like epithelium [PDF]
Environmental Health and Toxicology, 2019 Disinfectants including polyhexamethylene guanidine phosphate (PHMG) and mixtures of chloromethylisothiazolinone/ methylisothiazolinone (CMIT/MIT) have been widely used in Korea to prevent microbial growth in the humidifier water, which triggered an ...
Juyoung Park, Handule Lee, Kwangsik Park
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