Results 21 to 30 of about 1,436 (176)

Development of a formaldehyde biosensor with application to synthetic methylotrophy

Biotechnology and Bioengineering, 2017
Formaldehyde is a prevalent environmental toxin and a key intermediate in single carbon metabolism. The ability to monitor formaldehyde concentration is, therefore, of interest for both environmental monitoring and for metabolic engineering of native and synthetic methylotrophs, but current methods suffer from low sensitivity, complex workflows, or ...
Benjamin M. Woolston, Timothy Roth, Ishwar Kohale, David R. Liu, Gregory Stephanopoulos   +4 more
openaire   +5 more sources

Identification of overoxidizing and non-overoxidizing NAD-dependent methanol dehydrogenases and implications for synthetic methylotrophy [PDF]

Nature Communications
Synthetic methylotrophy offers opportunities for sustainable chemical and biofuel production. While recently established methylotrophic E. coli can grow on methanol, undesirable formate accumulation occurs during growth and bioproduction.
Philipp Keller, Emese Hegedis, Benedikt Jäger, Simon H. Rüdisser, Hedwig Schultz, Lars A. Büchel, Andrea M. Ochsner, Timothy Bradley, Michael A. Reiter, Donald Hilvert, Julia A. Vorholt   +10 more
doaj   +2 more sources

Fruit function beyond dispersal: effect of fruit decomposition on the plant microbiome assembly. [PDF]

New Phytol
Summary The evolutionary role of fruits has primarily been linked to seed dispersal. However, their influence on the soil and plant microbiomes subsequent to their decomposition has received no attention. We hypothesized that fruit decomposition alters the soil microbiome, and consequently the plant microbiome and performance.
Hoefle D, Ramakrishnan DK, Holländer MA, Kiplimo D, Konzag W, Schena L, Malacrinò A, Tack AJM, Abdelfattah A.   +8 more
europepmc   +2 more sources

Synthetic methylotrophic yeasts for the sustainable fuel and chemical production [PDF]

Biotechnology for Biofuels and Bioproducts, 2022
Global energy-related emissions, in particular carbon dioxide, are rapidly increasing. Without immediate and strong reductions across all sectors, limiting global warming to 1.5 °C and thus mitigating climate change is beyond reach.
Vanessa Wegat, Jonathan T. Fabarius, Volker Sieber   +2 more
doaj   +2 more sources

Aromatic acid metabolism in Methylobacterium extorquens reveals interplay between methylotrophic and heterotrophic pathways [PDF]

Applied and Environmental Microbiology
Efforts toward microbial conversion of lignin to value-added products face many challenges because lignin’s methoxylated aromatic monomers release toxic C1 byproducts such as formaldehyde.
Alekhya M. Govindaraju, Norma Cecilia Martinez-Gomez   +1 more
doaj   +2 more sources

Role of Methylotrophy During Symbiosis Between Methylobacterium nodulans and Crotalaria podocarpa

Molecular Plant-Microbe Interactions, 2005
Some rare leguminous plants of the genus Crotalaria are specifically nodulated by the methylotrophic bacterium Methylobacterium nodulans. In this study, the expression and role of bacterial methylotrophy were investigated during symbiosis between M ...
Philippe Jourand, Adeline Renier, Sylvie Rapior, Sergio Miana de Faria, Yves Prin, Antoine Galiana, Eric Giraud, Bernard Dreyfus   +7 more
doaj   +2 more sources

Lanthanide-Dependent Regulation of Methylotrophy in Methylobacterium aquaticum Strain 22A

mSphere, 2018
Methylobacterium species are representative of methylotrophic bacteria. Their genomes usually encode two types of methanol dehydrogenases (MDHs): MxaF and XoxF.
Sachiko Masuda, Yutaka Suzuki, Yoshiko Fujitani, Ryoji Mitsui, Tomoyuki Nakagawa, Masaki Shintani, Akio Tani   +6 more
doaj   +2 more sources

Methylotrophy: A great asset in symbiosis process?

, 2006
The bacterial genus Methylobacterium belongs to the [alpha]-proteobacteria. The main feature of members of this genus is their ability to oxidize methanol, a methylotrophic property based on the presence of methanol dehydrogenase (MDH). Recently, strains isolated from three Crotalaria spp.
Renier, Adeline, Rapior, Sylvie, Prin, Yves, Galiana, Antoine, Giraud, Eric, Dreyfus, Bernard, Jourand, Philippe   +6 more
openaire   +2 more sources

Hyperaccumulation of Gadolinium by Methylorubrum extorquens AM1 Reveals Impacts of Lanthanides on Cellular Processes Beyond Methylotrophy

Frontiers in Microbiology, 2022
Lanthanides (Ln) are a new group of life metals, and many questions remain regarding how they are acquired and used in biology. Methylotrophic bacteria can acquire, transport, biomineralize, and use Ln as part of a cofactor complex with pyrroloquinoline ...
Nathan M. Good, Harvey D. Lee, Harvey D. Lee, Emily R. Hawker, Morgan Z. Su, Assaf A. Gilad, Assaf A. Gilad, Assaf A. Gilad, N. Cecilia Martinez-Gomez   +8 more
doaj   +1 more source

A Methylotrophic Bacterium Growing with the Antidiabetic Drug Metformin as Its Sole Carbon, Nitrogen and Energy Source

Microorganisms, 2022
Metformin is one of the most prescribed antidiabetic agents worldwide and is also considered for other therapeutic applications including cancer and endocrine disorders. It is largely unmetabolized by human enzymes and its presence in the environment has
Pauline Chaignaud, Christelle Gruffaz, Adrien Borreca, Stéphanie Fouteau, Lauriane Kuhn, Jérémy Masbou, Zoé Rouy, Philippe Hammann, Gwenaël Imfeld, David Roche, Stéphane Vuilleumier   +10 more
doaj   +1 more source