Results 1 to 10 of about 125,711 (246)

Beneficial Effects of Pulse Methylprednisolone Therapy in COVID-19 Patients at Risk of Hyperinflammatory Response. [PDF]

Cureus
Dandiganahalli Channappa J, Kumar J.
europepmc   +3 more sources

Association of Intravenous Immunoglobulins Plus Methylprednisolone vs Immunoglobulins Alone With Course of Fever in Multisystem Inflammatory Syndrome in Children.

Journal of the American Medical Association (JAMA), 2021
Importance Multisystem inflammatory syndrome in children (MIS-C) is the most severe pediatric disease associated with severe acute respiratory syndrome coronavirus 2 infection, potentially life-threatening, but the optimal therapeutic strategy remains ...
N. Ouldali, J. Toubiana, D. Antona, E. Javouhey, F. Madhi, M. Lorrot, P. Léger, C. Galeotti, C. Claude, A. Wiedemann, Noémie Lachaume, C. Ovaert, Morgane Dumortier, J. Kahn, A. Mandelcwajg, Lucas Percheron, B. Biot, Jeanne Bordet, Marie Girardin, D. Yang, M. Grimaud, M. Oualha, S. Allali, F. Bajolle, C. Beyler, U. Meinzer, M. Levy, A. Paulet, C. Levy, R. Cohen, A. Belot, F. Angoulvant   +31 more
semanticscholar   +1 more source

Prehospital high-dose methylprednisolone in resuscitated out-of-hospital cardiac arrest patients (STEROHCA): a randomized clinical trial

Intensive Care Medicine, 2023
Purpose Patients who are successfully resuscitated following out-of-hospital cardiac arrest (OHCA) are still at a high risk of neurological damage and death.
L. Obling, R. Beske, M. Meyer, J. Grand, S. Wiberg, B. Nyholm, J. Josiassen, F. Sondergaard, Thomas Mohr, Anders Damm-Hejmdal, M. Bjerre, R. Frikke-Schmidt, F. Folke, J. Møller, J. Kjaergaard, C. Hassager   +15 more
semanticscholar   +1 more source

Low-dose methylprednisolone treatment in critically ill patients with severe community-acquired pneumonia

Intensive Care Medicine, 2022
Severe community-acquired pneumonia (CAP) requiring intensive care unit admission is associated with significant acute and long-term morbidity and mortality.
G. Meduri, M. Shih, Lisa Bridges, T. Martin, A. El‐Solh, N. Seam, A. Davis-Karim, R. Umberger, A. Anzueto, P. Sriram, Charlie Lan, M. Restrepo, J. Guardiola, Teresa Buck, David P. Johnson, A. Suffredini, W. Bell, Julia Lin, Lan Zhao, Lauren Uyeda, Lori Nielsen, Grant D. Huang   +21 more
semanticscholar   +1 more source

Methylprednisolone or dexamethasone, which one is superior corticosteroid in the treatment of hospitalized COVID-19 patients: a triple-blinded randomized controlled trial

BMC Infectious Diseases, 2021
Background Although almost a year has passed since the Coronavirus disease 2019 (COVID-19) outbreak and promising reports of vaccines have been presented, we still have a long way until these measures are available for all.
Keivan Ranjbar, M. Moghadami, A. Mirahmadizadeh, M. Fallahi, V. Khaloo, Reza Shahriarirad, A. Erfani, Zohre Khodamoradi, Mohammad Hasan Gholampoor Saadi   +8 more
semanticscholar   +1 more source

Dexamethasone vs methylprednisolone high dose for Covid-19 pneumonia

PLoS ONE, 2021
Background There is no effective therapy for the severe acute respiratory syndrome by coronavirus 2 (SARS-CoV2) responsible for the Coronavirus disease 2019 (Covid-19).
M. Pinzón, S. Ortiz, Héctor Holguín, J. Betancur, Doris Cardona Arango, Henry Laniado, Carolina Arias Arias, B. Muñoz, Julián Quiceno, Daniel Jaramillo, Zoraida Ramirez   +10 more
semanticscholar   +1 more source

Proptosis and Diplopia Response With Teprotumumab and Placebo vs the Recommended Treatment Regimen With Intravenous Methylprednisolone in Moderate to Severe Thyroid Eye Disease

JAMA ophthalmology, 2022
This meta-analysis conducts a matching-adjusted indirect comparison of teprotumumab vs intravenous methylprednisolone vs placebo in patients with moderate-to-severe thyroid eye disease.
Raymond S. Douglas, R. Dailey, P. Subramanian, Giuseppe Barbesino, Shoaib Ugradar, Ryan Batten, R. Qadeer, C. Cameron   +7 more
semanticscholar   +1 more source

Intravenous methylprednisolone pulses in hospitalised patients with severe COVID-19 pneumonia: a double-blind, randomised, placebo-controlled trial

European Respiratory Journal, 2022
Rationale Pulse glucocorticoid therapy is used in hyperinflammation related to coronavirus disease 2019 (COVID-19). We evaluated the efficacy and safety of pulse intravenous methylprednisolone in addition to standard treatment in COVID-19 pneumonia ...
C. Salvarani, M. Massari, M. Costantini, D. Merlo, Gabriella Lucia Mariani, Pierluigi Viale, S. Nava, G. Guaraldi, G. Dolci, L. Boni, L. Savoldi, P. Bruzzi, Caterina Turrà, M. Catanoso, A. Marata, Chiara Barbieri, Annamaria Valcavi, Francesca Franzoni, S. Cavuto, G. Mazzi, R. Corsini, F. Trapani, A. Bartoloni, E. Barisione, Chiara Barbieri, G. Burastero, A. Pan, W. Inojosa, R. Scala, C. Burattini, F. Luppi, M. Codeluppi, Kamal Eldin Tarek, G. Cenderello, M. Salio, G. Foti, R. Dongilli, G. Bajocchi, E. Negri, G. Ciusa, Giacomo Fornaro, I. Bassi, L. Zammarchi, T. Aloè, N. Facciolongo   +44 more
semanticscholar   +1 more source

Prolonged higher dose methylprednisolone versus conventional dexamethasone in COVID-19 pneumonia: a randomised controlled trial (MEDEAS)

European Respiratory Journal, 2022
Background Dysregulated systemic inflammation is the primary driver of mortality in severe coronavirus disease 2019 (COVID-19) pneumonia. Current guidelines favour a 7–10-day course of any glucocorticoid equivalent to dexamethasone 6 mg daily.
F. Salton, P. Confalonieri, S. Centanni, M. Mondoni, N. Petrosillo, P. Bonfanti, G. Lapadula, D. Lacedonia, A. Voza, N. Carpenè, M. Montico, Nicolò Reccardini, G. Meduri, B. Ruaro, M. Confalonieri, Gloria Maria Giulia Chiara Stefano Riccardo Alessia Giova Citton Lapadula Bozzi Tavano Pozzan Andrisano Jabe   +15 more
semanticscholar   +1 more source

Methylprednisolone for Heart Surgery in Infants - A Randomized, Controlled Trial.

New England Journal of Medicine, 2022
BACKGROUND Although perioperative prophylactic glucocorticoids have been used for decades, whether they improve outcomes in infants after heart surgery with cardiopulmonary bypass is unknown. METHODS We conducted a multicenter, prospective, randomized,
K. Hill, P. Kannankeril, J. Jacobs, H. Baldwin, M. Jacobs, Sean M. O'Brien, David P Bichel, E. Graham, Brian Blasiole, Ashraf Resheidat, Adil Husain, S. R. Kumar, J. Kirchner, D. Gallup, J. Turek, M. Bleiweis, B. Mettler, A. Benscoter, Eric L. Wald, T. Karamlou, Andrew H. Van Bergen, David Overman, P. Eghtesady, Ryan Butts, J. S. Kim, J. Scott, B. Anderson, Michael F Swartz, P. McConnell, D. Vener, Jennifer S. Li   +30 more
semanticscholar   +1 more source