Results 1 to 10 of about 167,693 (338)

Related Fluoxetine and Methylprednisolone Changes of TNF-α and IL-6 Expression in The Hypothyroidism Rat Model of Spinal Cord Injury [PDF]

Cell Journal, 2021
Objective: Spinal cord injury (SCI) is a serious clinical condition that leads to disability. Following primary injury, proinflammatory cytokines play an important role in the subsequent secondary events.
Atousa Zirak, Maryam Soleimani, Seyed Behnamedin Jameie, Mohammad Amin Abdollahifar, Fatemeh Fadaei Fathabadi, Sajad Hassanzadeh, Emran Esmaeilzadeh, Mohammad Hadi Farjoo, Mohsen Norouzian   +8 more
doaj   +1 more source

Acyclovir with Steroid and Steroid Alone in the Treatment of Idiopathic Facial Nerve Palsy: A Randomised Double-blinded Clinical Study from a Tertiary Care Centre, Chennai, India [PDF]

Journal of Clinical and Diagnostic Research, 2023
Introdutcion: Idiopathic palsy of facial nerve is an acute disease which causes lower motor neuron palsy characterised by facial asymmetry leads to psychological effects and limits one’s social life.
SR Kartrthika, K Priya, S Rajasekaran, D Balaji   +3 more
doaj   +1 more source

Association of Intravenous Immunoglobulins Plus Methylprednisolone vs Immunoglobulins Alone With Course of Fever in Multisystem Inflammatory Syndrome in Children.

Journal of the American Medical Association (JAMA), 2021
Importance Multisystem inflammatory syndrome in children (MIS-C) is the most severe pediatric disease associated with severe acute respiratory syndrome coronavirus 2 infection, potentially life-threatening, but the optimal therapeutic strategy remains ...
N. Ouldali, J. Toubiana, D. Antona, E. Javouhey, F. Madhi, M. Lorrot, P. Léger, C. Galeotti, C. Claude, A. Wiedemann, Noémie Lachaume, C. Ovaert, Morgane Dumortier, J. Kahn, A. Mandelcwajg, Lucas Percheron, B. Biot, Jeanne Bordet, Marie Girardin, D. Yang, M. Grimaud, M. Oualha, S. Allali, F. Bajolle, C. Beyler, U. Meinzer, M. Levy, A. Paulet, C. Levy, R. Cohen, A. Belot, F. Angoulvant   +31 more
semanticscholar   +1 more source

Effect of Oral Methylprednisolone on Decline in Kidney Function or Kidney Failure in Patients With IgA Nephropathy: The TESTING Randomized Clinical Trial.

Journal of the American Medical Association (JAMA), 2022
Importance The effect of glucocorticoids on major kidney outcomes and adverse events in IgA nephropathy has been uncertain. Objective To evaluate the efficacy and adverse effects of methylprednisolone in patients with IgA nephropathy at high risk of ...
J. Lv, M. Wong, M. Hladunewich, V. Jha, L. Hooi, H. Monaghan, Minghui Zhao, S. Barbour, M. Jardine, H. Reich, D. Cattran, R. Glassock, A. Levin, D. Wheeler, M. Woodward, L. Billot, S. Stepien, Kris Rogers, T. Chan, Zhi-Hong Liu, David W. Johnson, A. Cass, J. Feehally, J. Floege, G. Remuzzi, Yangfeng Wu, R. Agarwal, Hong Zhang, V. Perkovic   +28 more
semanticscholar   +1 more source

Methylprednisolone Induces Neuro-Protective Effects via the Inhibition of A1 Astrocyte Activation in Traumatic Spinal Cord Injury Mouse Models

Frontiers in Neuroscience, 2021
Traumatic spinal cord injury (TSCI) leads to pathological changes such as inflammation, edema, and neuronal apoptosis. Methylprednisolone (MP) is a glucocorticoid that has a variety of beneficial effects, including decreasing inflammation and ischemic ...
Hong-jun Zou, Shi-Wu Guo, Lin Zhu, Xu Xu, Jin-bo Liu   +4 more
doaj   +1 more source

Low-dose methylprednisolone treatment in critically ill patients with severe community-acquired pneumonia

Intensive Care Medicine, 2022
Severe community-acquired pneumonia (CAP) requiring intensive care unit admission is associated with significant acute and long-term morbidity and mortality.
G. Meduri, M. Shih, Lisa Bridges, T. Martin, A. El‐Solh, N. Seam, A. Davis-Karim, R. Umberger, A. Anzueto, P. Sriram, Charlie Lan, M. Restrepo, J. Guardiola, Teresa Buck, David P. Johnson, A. Suffredini, W. Bell, Julia Lin, Lan Zhao, Lauren Uyeda, Lori Nielsen, Grant D. Huang   +21 more
semanticscholar   +1 more source

Prehospital high-dose methylprednisolone in resuscitated out-of-hospital cardiac arrest patients (STEROHCA): a randomized clinical trial

Intensive Care Medicine, 2023
Purpose Patients who are successfully resuscitated following out-of-hospital cardiac arrest (OHCA) are still at a high risk of neurological damage and death.
L. Obling, R. Beske, M. Meyer, J. Grand, S. Wiberg, B. Nyholm, J. Josiassen, F. Sondergaard, Thomas Mohr, Anders Damm-Hejmdal, M. Bjerre, R. Frikke-Schmidt, F. Folke, J. Møller, J. Kjaergaard, C. Hassager   +15 more
semanticscholar   +1 more source

Methylprednisolone, venous thromboembolism, and association with heparin to 30 days in hospital survival in severe Covid-19 pneumonia

BMC Pulmonary Medicine, 2022
Background Mortality in severe COVID-19 pneumonia is associated with thrombo-inflammation. Corticosteroids are given to attenuate the inflammation, but they are associated with thrombosis.
Ronaldo C. Go, Themba Nyirenda, Maryam Bojarian, Davood K. Hosseini, Mehek Rahim, Kevin Kim, Keith M. Rose   +6 more
doaj   +1 more source

Kinetics of Severity Biomarkers and Immunological Features of Methylprednisolone Therapy for Severe COVID-19 Patients

Frontiers in Immunology, 2022
In contrast to dexamethasone, the clinical efficacy of methylprednisolone (MP) remains controversial, and a systems biology study on its mechanism is lacking. In this study, a total of 38 severe COVID-19 patients were included. The demographics, clinical
Qinghong Fan, Kai Deng, Huang Huang, Ruiying He, Xizi Deng, Yun Lan, Yizhou Tan, Weilie Chen, Yaping Wang, Xilong Deng, Fengyu Hu, Feng Li, Feng Li   +12 more
doaj   +1 more source

Methylprednisolone or dexamethasone, which one is superior corticosteroid in the treatment of hospitalized COVID-19 patients: a triple-blinded randomized controlled trial

BMC Infectious Diseases, 2021
Background Although almost a year has passed since the Coronavirus disease 2019 (COVID-19) outbreak and promising reports of vaccines have been presented, we still have a long way until these measures are available for all.
Keivan Ranjbar, M. Moghadami, A. Mirahmadizadeh, M. Fallahi, V. Khaloo, Reza Shahriarirad, A. Erfani, Zohre Khodamoradi, Mohammad Hasan Gholampoor Saadi   +8 more
semanticscholar   +1 more source